Kinase Profiling Inhibitor Database

This is a searchable database of specificities of 55684 commonly used signal transduction inhibitors. These results have been provided by the International Centre for Kinase profiling within the MRC Protein Phosphorylation Unit at the University of Dundee.

We strongly recommend undertaking kinase profiling of any kinase inhibitor to be used in a biological experiment. It is essential to have a good feel for the specificity of the kinase inhibitor you are working with in order to be able to properly interpret your data.

If you have additional kinase inhibitors that you would like the International Centre for Kinase profiling team to profile for you please contact us here for further details.

If you have any feedback or suggestions on how to improve this resource we welcome your input. Pass on your ideas to us here.

Inhibitor Brutto MW Action Reference Screen Conc % Activity Remaining
AX 20017   C13H16N2O2S 264.34 PknG Walburger A (2004) Science 304 1800-1804


10.00 79
AZD8055   C25H31N5O4 465.50 mTOR C1, mTOR C2 Chresta C.M. (2010) Cancer Res. 70 288-298
Sini P. (2010) Autophagy 6(4)

0.10 105
AZD8055   C25H31N5O4 465.50 mTOR C1, mTOR C2 Chresta C.M. (2010) Cancer Res. 70 288-298
Sini P. (2010) Autophagy 6(4)

1.00 95
BAY 61-3606 C20H18N6O3 · xHCl · yH2O 390.40 Syk Yamamoto N. (2003) J. Pharmacol. Exp. Ther. 306 1174-1181


10.00 51
BAY 61-3606 C20H18N6O3 · xHCl · yH2O 390.40 Syk Yamamoto N. (2003) J. Pharmacol. Exp. Ther. 306 1174-1181


1.00 63
Bay 65-1942   C22H26ClN3O4 431.91 IKKb Ziegelbauer K. (2005) British Journal of Pharmacology 145 178-192 (compound A)
Moss N.C. (2007) Am J Physiol Heart Circ Physiol 293 H2248-53

10.00 49
Bay 65-1942   C22H26ClN3O4 431.91 IKKb Ziegelbauer K. (2005) British Journal of Pharmacology 145 178-192 (compound A)
Moss N.C. (2007) Am J Physiol Heart Circ Physiol 293 H2248-53

1.00 94
BAY-11-7082   C10H9NO2S 207.20 NFKBIA Kamthong P.J. (2001) Biochem. J. 356
Izban K.F. (2000) Hum. Pathol. 31 1482
WO2003072038
1.00 127
BAY-11-7082   C10H9NO2S 207.20 NFKBIA Kamthong P.J. (2001) Biochem. J. 356
Izban K.F. (2000) Hum. Pathol. 31 1482
WO2003072038
10.00 158
BI 2536   C28H39N7O3 521.65 PLK1 Steegmaier M. (2007) Current Biology 17 316-322


1.00 109