Inhibitor | Bay 65-1942  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	87	0
BRSK2	89	2
BTK	100	7
CAMK1	54	3
CAMKK beta	94	0
CDK2-Cyclin A	58	5
CHK1	102	4
CHK2	77	6
CK1 delta	81	5
CK2	95	7
CSK	91	11
DYRK1A	99	3
DYRK2	99	8
DYRK3	71	7
EF2K	88	6
EPH-A2	96	7
EPH-B3	89	13
ERK1	98	22
ERK2	81	0
ERK8	53	1
FGF-R1	96	6
GSK3 beta	126	6
HIPK2	84	4
IGF-1R	80	18
IKK beta	28	17
IKK epsilon	83	0
IR	94	1
IRR	78	6
JNK1	76	4
JNK2	90	6
Lck	88	4
MAPKAP-K2	120	37
MARK3	100	8
MELK	79	23
MKK1	79	0
MNK1	97	8
MNK2	98	5
MSK1	71	4
MST2	84	3
MST4	105	4
NEK2a	83	6
NEK6	98	3
p38 alpha MAPK	91	0
p38 beta MAPK	91	1
p38 delta MAPK	88	7
p38 gamma MAPK	85	0
PAK4	89	13
PAK5	82	1
PAK6	72	1
PDK1	106	3
PHK	70	8
PIM1	76	7
PIM2	88	24
PIM3	44	2
PKA	79	6
PKB alpha	87	1
PKB beta	88	11
PKC alpha	77	7
PKC zeta	76	47
PKD1	79	1
PLK1	83	7
PRAK	74	1
PRK2	69	7
ROCK 2	73	0
RSK1	83	0
RSK2	80	8
S6K1	102	17
SGK1	55	4
SmMLCK	76	6
Src	91	3
SRPK1	98	6
SYK	106	13
TBK1	91	2
VEGFR1	112	2
YES1	94	2

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	54	5
BRSK2	45	4
BTK	83	0
CAMK1	13	0
CAMKK beta	78	9
CDK2-Cyclin A	14	0
CHK1	88	4
CHK2	46	7
CK1 delta	43	3
CK2	70	0
CSK	92	5
DYRK1A	82	6
DYRK2	77	9
DYRK3	24	1
EF2K	67	0
EPH-A2	84	3
EPH-B3	93	9
ERK1	86	3
ERK2	74	14
ERK8	10	1
FGF-R1	79	2
GSK3 beta	99	6
HIPK2	34	3
IGF-1R	71	29
IKK beta	12	1
IKK epsilon	74	6
IR	96	9
IRR	45	4
JNK1	61	0
JNK2	93	5
Lck	74	4
MAPKAP-K2	147	91
MARK3	94	2
MELK	58	17
MKK1	62	7
MNK1	74	5
MNK2	87	7
MSK1	31	2
MST2	67	2
MST4	85	13
NEK2a	81	8
NEK6	93	11
p38 alpha MAPK	78	7
p38 beta MAPK	74	12
p38 delta MAPK	73	4
p38 gamma MAPK	66	2
PAK4	54	8
PAK5	72	1
PAK6	78	1
PDK1	100	7
PHK	21	1
PIM1	15	0
PIM2	40	12
PIM3	7	1
PKA	65	4
PKB alpha	55	15
PKB beta	61	3
PKC alpha	31	5
PKC zeta	10	1
PKD1	48	1
PLK1	87	2
PRAK	58	13
PRK2	36	0
ROCK 2	39	0
RSK1	46	2
RSK2	53	3
S6K1	68	0
SGK1	13	0
SmMLCK	37	5
Src	83	1
SRPK1	65	5
SYK	91	17
TBK1	84	4
VEGFR1	116	1
YES1	49	4