Inhibitor | AZD8055  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	98	4
BRSK2	87	15
BTK	89	1
CAMK1	76	0
CAMKK beta	98	13
CDK2-Cyclin A	100	1
CHK1	90	3
CHK2	102	12
CK1 delta	92	11
CK2	112	12
CSK	93	5
DYRK1A	84	11
DYRK2	107	2
DYRK3	91	5
EF2K	91	16
EPH-A2	93	2
EPH-B3	89	14
ERK1	91	11
ERK2	80	1
ERK8	111	7
FGF-R1	129	4
GSK3 beta	94	13
HIPK2	118	9
IGF-1R	131	3
IKK beta	93	1
IKK epsilon	118	0
IR	83	9
IRR	92	1
JNK1	94	5
JNK2	82	8
Lck	82	4
MAPKAP-K2	98	6
MARK3	104	6
MELK	91	18
MKK1	112	16
MNK1	132	20
MNK2	86	4
MSK1	91	14
MST2	98	2
MST4	87	9
NEK2a	96	11
NEK6	86	13
p38 alpha MAPK	80	2
p38 beta MAPK	106	5
p38 delta MAPK	94	15
p38 gamma MAPK	94	15
PAK4	108	9
PAK5	94	10
PAK6	80	1
PDK1	98	7
PHK	93	6
PIM1	99	16
PIM2	103	13
PIM3	97	4
PKA	81	3
PKB alpha	94	3
PKB beta	84	10
PKC alpha	97	2
PKC zeta	95	4
PKD1	111	7
PLK1	98	12
PRAK	93	0
PRK2	102	11
ROCK 2	106	5
RSK1	90	4
RSK2	81	3
S6K1	106	6
SGK1	118	13
SmMLCK	93	2
Src	102	8
SRPK1	84	9
SYK	96	2
TBK1	104	8
VEGFR1	80	7
YES1	105	5

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	100	10
BRSK2	94	16
BTK	83	10
CAMK1	84	5
CAMKK beta	90	5
CDK2-Cyclin A	102	7
CHK1	101	15
CHK2	88	7
CK1 delta	96	6
CK2	113	2
CSK	101	14
DYRK1A	83	14
DYRK2	103	15
DYRK3	99	9
EF2K	100	25
EPH-A2	92	11
EPH-B3	85	5
ERK1	89	21
ERK2	92	17
ERK8	102	14
FGF-R1	122	2
GSK3 beta	87	12
HIPK2	105	13
IGF-1R	107	2
IKK beta	91	12
IKK epsilon	107	0
IR	94	21
IRR	94	12
JNK1	99	6
JNK2	84	3
Lck	88	6
MAPKAP-K2	96	3
MARK3	53	72
MELK	99	27
MKK1	104	6
MNK1	102	14
MNK2	102	3
MSK1	91	7
MST2	106	10
MST4	101	10
NEK2a	100	7
NEK6	130	41
p38 alpha MAPK	87	0
p38 beta MAPK	89	11
p38 delta MAPK	89	20
p38 gamma MAPK	105	0
PAK4	108	17
PAK5	87	1
PAK6	86	7
PDK1	98	10
PHK	94	15
PIM1	99	4
PIM2	98	10
PIM3	95	9
PKA	89	8
PKB alpha	93	8
PKB beta	80	10
PKC alpha	101	5
PKC zeta	88	2
PKD1	124	3
PLK1	99	2
PRAK	91	16
PRK2	91	15
ROCK 2	128	31
RSK1	88	16
RSK2	84	7
S6K1	105	13
SGK1	110	10
SmMLCK	92	10
Src	105	13
SRPK1	81	7
SYK	99	9
TBK1	116	9
VEGFR1	76	5
YES1	95	4