Inhibitor | BAY-11-7082  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	94	5
Aurora A	103	14
Aurora B	82	12
BRSK1	80	11
BRSK2	106	4
BTK	81	3
CAMK1	59	13
CAMKK beta	102	6
CDK2-Cyclin A	84	4
CHK1	113	18
CHK2	99	6
CK1 delta	101	3
CK2	103	2
CLK2	103	1
CSK	98	2
DAPK1	107	13
DYRK1A	96	16
DYRK2	96	0
DYRK3	108	3
EF2K	103	13
EPH-A2	98	6
EPH-A4	106	1
EPH-B2	101	8
EPH-B3	92	1
EPH-B4	125	4
ERK1	121	5
ERK2	84	5
ERK8	110	7
FGF-R1	90	5
GCK	103	1
GSK3 beta	93	6
HER4	117	11
HIPK1	108	18
HIPK2	97	4
HIPK3	90	3
IGF-1R	77	40
IKK beta	101	10
IKK epsilon	103	1
IR	99	7
IRAK4	95	1
IRR	99	1
JAK2	99	9
JNK1	91	7
JNK2	85	3
JNK3	107	20
Lck	108	10
LKB1	93	1
MAPKAP-K2	93	7
MAPKAP-K3	89	8
MARK1	104	2
MARK2	80	11
MARK3	90	3
MARK4	95	1
MEKK1	88	2
MELK	101	6
MINK1	103	3
MKK1	105	8
MLK1	86	13
MLK3	93	7
MNK1	117	16
MNK2	95	3
MSK1	95	6
MST2	90	16
MST4	89	6
NEK2a	104	0
NEK6	100	12
NUAK1	93	5
p38 alpha MAPK	100	13
p38 beta MAPK	81	15
p38 delta MAPK	95	8
p38 gamma MAPK	112	9
PAK2	96	15
PAK4	83	10
PAK5	97	7
PAK6	87	4
PDK1	91	4
PHK	91	3
PIM1	104	5
PIM2	103	9
PIM3	74	6
PKA	91	0
PKB alpha	102	4
PKB beta	86	15
PKC alpha	95	6
PKC zeta	100	10
PKD1	83	1
PLK1	108	1
PRAK	98	13
PRK2	100	0
RIPK2	109	1
ROCK 2	96	7
RSK1	98	11
RSK2	79	2
S6K1	100	16
SGK1	88	10
SmMLCK	104	13
Src	177	4
SRPK1	107	6
SYK	94	3
TAK1	108	24
TBK1	94	1
TrkA	124	5
TTK	107	14
VEGFR1	80	1
YES1	127	34

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	76	4
ASK1	101	5
Aurora A	14	0
Aurora B	101	14
BRSK1	73	6
BRSK2	41	7
BTK	58	6
CAMK1	19	2
CAMKK beta	99	1
CDK2-Cyclin A	87	8
CHK1	79	2
CHK2	86	0
CK1 delta	97	6
CK2	104	4
CLK2	96	6
CSK	92	10
DAPK1	73	6
DYRK1A	86	3
DYRK2	78	5
DYRK3	96	3
EF2K	85	4
EPH-A2	75	7
EPH-A4	95	4
EPH-B1	94	3
EPH-B2	112	4
EPH-B3	97	6
EPH-B4	87	5
ERK1	102	8
ERK2	79	2
ERK8	101	6
FGF-R1	92	11
GCK	67	6
GSK3 beta	101	3
HER4	68	2
HIPK1	82	4
HIPK2	96	5
HIPK3	88	7
IGF-1R	95	2
IKK beta	87	2
IKK epsilon	35	1
IR	105	10
IRAK4	92	2
IRR	87	3
JAK2	84	3
JNK1	99	1
JNK2	78	5
JNK3	83	0
Lck	107	4
LKB1	75	4
MAPKAP-K2	92	0
MAPKAP-K3	75	0
MARK1	100	1
MARK2	70	1
MARK3	95	7
MARK4	58	3
MEKK1	94	6
MELK	89	13
MINK1	27	4
MKK1	92	11
MKK2	89	7
MKK6	85	1
MLK1	78	2
MLK3	93	8
MNK1	89	1
MNK2	96	11
MSK1	79	5
MST2	51	5
MST4	61	6
NEK2a	88	10
NEK6	92	1
NUAK1	20	1
p38 alpha MAPK	88	7
p38 beta MAPK	87	4
p38 delta MAPK	93	1
p38 gamma MAPK	97	6
PAK2	83	5
PAK4	95	10
PAK5	89	8
PAK6	80	7
PDK1	90	4
PHK	106	5
PIM1	71	3
PIM2	83	7
PIM3	82	1
PKA	89	6
PKB alpha	90	4
PKB beta	8	1
PKC alpha	75	0
PKC zeta	92	2
PKD1	72	5
PLK1	93	5
PRAK	76	3
PRK2	70	5
RIPK2	80	0
ROCK 2	82	7
RSK1	86	1
RSK2	8	0
S6K1	84	2
SGK1	99	6
SmMLCK	85	9
Src	162	6
SRPK1	90	2
SYK	78	1
TAK1	99	6
TAO1	81	3
TBK1	75	6
TrkA	87	7
TTK	86	3
VEGFR1	40	9
YES1	158	14