Kinase Profiling Inhibitor Database

This is a searchable database of specificities of 55684 commonly used signal transduction inhibitors. These results have been provided by the International Centre for Kinase profiling within the MRC Protein Phosphorylation Unit at the University of Dundee.

We strongly recommend undertaking kinase profiling of any kinase inhibitor to be used in a biological experiment. It is essential to have a good feel for the specificity of the kinase inhibitor you are working with in order to be able to properly interpret your data.

If you have additional kinase inhibitors that you would like the International Centre for Kinase profiling team to profile for you please contact us here for further details.

If you have any feedback or suggestions on how to improve this resource we welcome your input. Pass on your ideas to us here.

Inhibitor Brutto MW Action Reference Screen Conc % Activity Remaining
STO 609   C19H10N2O3 • CH3CO2H 374.40 CaMKK Levine Y. (2007) J. Biol. Chem. 282 20351
Tokumitsu H. (2003) J. Biol. Chem. 278 10908

0.10 50
STOCK1S-50699   C29H31IN2S2 598.60 WNK Mori T. (2013) Biochem J. 1 455(3) 339-45


 10.00 105
STOCK1S-50699   C29H31IN2S2 598.60 WNK Mori T. (2013) Biochem J. 1 455(3) 339-45


 1.00 106
STOCK2S-26016   C20H19N3O2 333.39 WNK Mori T. (2013) Biochem J. 1 455(3) 339-45


 1.00 92
STOCK2S-26016   C20H19N3O2 333.39 WNK Mori T. (2013) Biochem J. 1 455(3) 339-45


 10.00 103
SU-5416 (VEGFR2 Kinase Inhibitor III)   C15H14N2O 238.30 VEGF-R Tille J.C. (2003) Exp. Cell Res. 285 286
Itokawa T. (2002) Mol. Cancer Ther. 1 295

1.00 73
SU-5416 (VEGFR2 Kinase Inhibitor III)   C15H14N2O 238.30 VEGF-R Tille J.C. (2003) Exp. Cell Res. 285 286
Itokawa T. (2002) Mol. Cancer Ther. 1 295

0.10 104
SU-6656   C19H21N3O3S 371.50 Src Bowman T. (2001) Proc. Natl. Acad. Sci. USA 98 7319
Blake R.A. (2000) Mol. Cell. Biol. 20 9018

1.00 3
SU-6656   C19H21N3O3S 371.50 Src Bowman T. (2001) Proc. Natl. Acad. Sci. USA 98 7319
Blake R.A. (2000) Mol. Cell. Biol. 20 9018

10.00 3
SU-6668   C18H18N2O3 310.35 Aurora Godl K. (2005) Cancer Res. 65 6919-6926.


 10.00 9