Inhibitor | SU-6656  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
SU-6656   C19H21N3O3S 371.50 330161-87-0 5312137 Src Bowman T. (2001) Proc. Natl. Acad. Sci. USA 98 7319 Blake R.A. (2000) Mol. Cell. Biol. 20 9018

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ABL 32 3
AMPK 17 0
AMPK (hum)
4
 1
ASK1 86 3
Aurora A
2
 1
Aurora B
3
 0
Aurora C
7
 0
BRK 26 5
BRSK1 13 1
BRSK2 13 1
BTK 62 9
CAMK1 101 2
CAMKK alpha 20 4
CAMKK beta 12 4
CDK2-Cyclin A 92 0
CDK9-Cyclin T1 101 9
CHK1 49 3
CHK2 14 1
CK1 delta 104 6
CK1 gamma 2 109 3
CK2 93 1
CLK2
5
 1
CSK 85 1
DAPK1 95 10
DDR2 31 1
DYRK1A 45 4
DYRK2 88 7
DYRK3 87 1
EF2K 91 7
EIF2AK3 101 0
EPH-A2 75 6
EPH-A4 64 12
EPH-B1 90 1
EPH-B2 91 2
EPH-B3 77 5
EPH-B4 70 6
ERK1 95 10
ERK2 75 6
ERK8 65 4
FGF-R1 37 4
GCK
7
 0
GSK3 beta 88 6
HER4 76 31
HIPK1 102 6
HIPK2 72 12
HIPK3 118 15
IGF-1R 96 25
IKK beta 89 13
IKK epsilon 33 0
IR 35 6
IRAK1
2
 0
IRAK4
10
 4
IRR 80 39
JAK2
2
 4
JNK1 83 9
JNK2 91 3
JNK3 104 7
Lck 12 0
LKB1 79 10
MAP4K3
1
 0
MAP4K5
4
 0
MAPKAP-K2 102 10
MAPKAP-K3 86 12
MARK1 45 18
MARK2 37 0
MARK3 35 4
MARK4 53 1
MEKK1 72 3
MELK 79 5
MINK1 58 34
MKK1 38 11
MKK2 56 4
MKK6 93 12
MLK1 33 6
MLK3 32 5
MNK1 111 6
MNK2 97 2
MPSK1 95 2
MSK1 98 5
MST2
7
 1
MST3 42 1
MST4 21 2
NEK2a 66 2
NEK6 106 8
NUAK1 56 75
OSR1 74 0
p38 alpha MAPK 85 2
p38 beta MAPK 88 7
p38 delta MAPK 89 7
p38 gamma MAPK 101 9
PAK2 99 3
PAK4 73 1
PAK5 75 2
PAK6 80 0
PDK1 104 20
PHK 52 6
PIM1 112 1
PIM2 106 6
PIM3 65 0
PKA 89 4
PKB alpha 102 4
PKB beta 103 14
PKC alpha 106 15
PKC gamma 101 4
PKC zeta 114 3
PKD1 102 4
PLK1 105 5
PRAK 83 15
PRK2 26 3
RIPK2 51 2
ROCK 2 46 2
RSK1 38 9
RSK2 66 11
S6K1 78 1
SGK1 92 15
SIK2 59 3
SIK3 54 12
SmMLCK 79 2
Src 12 4
SRPK1 19 5
STK33 30 1
SYK 71 8
TAK1 55 6
TAO1 60 2
TBK1 66 3
TESK1 51 11
TIE2 71 14
TLK1 101 12
TrkA 49 66
TSSK1 50 23
TTBK1 91 9
TTBK2 74 17
TTK 58 2
ULK1
1
 1
ULK2
8
 1
VEGFR1 64 58
WNK1 104 5
YES1
3
 0
ZAP70 102 1
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ABL 36 5
AMPK
10
 2
AMPK (hum)
3
 3
ASK1 66 4
Aurora A
3
 2
Aurora B
2
 0
BRK 64 12
BRSK1 18 2
BRSK2
6
 2
BTK 53 5
CAMK1 78 3
CAMKK beta
9
 1
CDK2-Cyclin A 68 39
CDK9-Cyclin T1 65 10
CHK1 55 10
CHK2 11 3
CK1 delta 74 4
CK1 gamma 2 100 10
CK2 94 11
CLK2
7
 1
CSK 44 10
DAPK1 83 7
DDR2 24 2
DYRK1A 30 7
DYRK2 87 2
DYRK3 85 14
EF2K 77 12
EIF2AK3 102 8
EPH-A2 41 0
EPH-A4 41 6
EPH-B1 89 3
EPH-B2 41 4
EPH-B3 37 2
EPH-B4 76 20
ERK1 94 12
ERK2 76 11
ERK8 29 3
FGF-R1 21 0
GCK
6
 1
GSK3 beta 76 20
HER4 90 5
HIPK1 90 8
HIPK2 66 9
HIPK3 107 6
IGF-1R 60 30
IKK beta 87 9
IKK epsilon 21 2
IR 29 16
IRAK1
1
 1
IRAK4
6
 1
IRR 59 3
JAK2
0
 2
JNK1 103 15
JNK2 90 2
JNK3 85 1
Lck 12 2
LKB1 96 16
MAP4K3
3
 1
MAP4K5
4
 0
MAPKAP-K2 102 16
MAPKAP-K3 64 1
MARK1 53 31
MARK2 75 23
MARK3 38 3
MARK4 21 0
MEKK1 75 12
MELK 80 10
MINK1 37 8
MKK1 28 2
MKK2 41 7
MKK6 82 9
MLK1 45 8
MLK3 25 3
MNK1 100 7
MNK2 89 10
MPSK1 98 3
MSK1 83 8
MST2
6
 2
MST3 23 2
MST4 51 48
NEK2a 57 14
NEK6 80 5
NUAK1
6
 0
OSR1 51 5
p38 alpha MAPK 80 0
p38 beta MAPK 80 5
p38 delta MAPK 88 6
p38 gamma MAPK 102 5
PAK2 90 2
PAK4 36 1
PAK5 95 11
PAK6 103 28
PDGFRA 31 7
PDK1 91 3
PHK 51 8
PIM1 104 5
PIM2 94 1
PIM3 84 11
PKA 82 1
PKB alpha 94 1
PKB beta 79 23
PKC alpha 95 1
PKC gamma 95 1
PKC zeta 100 3
PKD1 108 14
PLK1 114 11
PRAK 62 2
PRK2 21 2
RIPK2 48 2
ROCK 2 19 3
RSK1 27 2
RSK2 62 0
S6K1 63 10
SGK1 69 15
SIK2 62 1
SIK3 51 0
SmMLCK 69 1
Src 11 4
SRPK1
6
 1
STK33 23 2
SYK 44 5
TAK1 56 6
TAO1 50 15
TBK1 56 8
TESK1 51 7
TIE2 74 3
TLK1 96 11
TrkA
5
 2
TSSK1 51 14
TTBK1 91 7
TTBK2 112 22
TTK 44 7
ULK1
2
 1
ULK2
7
 7
VEGFR1 19 6
WNK1 98 8
YES1
3
 1
ZAP70 103 3