Inhibitor | STO 609  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	64	7
ASK1	96	15
Aurora A	117	3
Aurora B	96	10
BRSK1	91	1
BRSK2	96	4
BTK	89	3
CAMK1	117	7
CAMKK beta	9	1
CDK2-Cyclin A	71	4
CHK1	101	1
CHK2	70	4
CK1 delta	47	1
CK2	85	6
CLK2	38	0
CSK	83	6
DAPK1	103	1
DYRK1A	44	0
DYRK2	88	0
DYRK3	74	0
EF2K	84	4
EPH-A2	91	8
EPH-A4	112	5
EPH-B1	70	5
EPH-B2	80	2
EPH-B3	78	9
EPH-B4	81	3
ERK1	117	11
ERK2	84	10
ERK8	38	0
FGF-R1	90	5
GCK	29	4
GSK3 beta	70	3
HER4	104	9
HIPK1	101	0
HIPK2	93	8
HIPK3	96	2
IGF-1R	98	6
IKK beta	79	1
IKK epsilon	88	5
IR	46	12
IRAK4	103	13
IRR	69	3
JAK2	86	2
JNK1	95	1
JNK2	99	12
JNK3	82	4
Lck	73	5
LKB1	76	13
MAPKAP-K2	99	6
MAPKAP-K3	90	4
MARK1	110	6
MARK2	98	5
MARK3	99	3
MARK4	81	3
MEKK1	103	11
MELK	90	13
MINK1	62	7
MKK1	81	5
MKK2	106	1
MKK6	92	6
MLK1	70	11
MLK3	90	0
MNK1	30	3
MNK2	112	3
MSK1	91	9
MST2	92	7
MST4	99	6
NEK2a	94	5
NEK6	90	6
NUAK1	69	11
p38 alpha MAPK	103	5
p38 beta MAPK	95	9
p38 delta MAPK	111	8
p38 gamma MAPK	96	5
PAK2	111	12
PAK4	87	8
PAK5	108	4
PAK6	95	0
PDK1	102	3
PHK	43	3
PIM1	100	7
PIM2	105	4
PIM3	106	5
PKA	87	0
PKB alpha	88	4
PKB beta	90	6
PKC alpha	105	12
PKC zeta	91	13
PKD1	101	3
PLK1	105	11
PRAK	102	3
PRK2	85	12
RIPK2	23	2
ROCK 2	88	1
RSK1	91	2
RSK2	108	6
S6K1	80	0
SGK1	84	8
SmMLCK	106	9
Src	76	5
SRPK1	102	5
SYK	92	6
TAK1	71	3
TAO1	103	11
TBK1	100	12
TrkA	51	2
TTK	86	6
VEGFR1	18	0
YES1	50	3

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	57	1
ASK1	103	5
Aurora A	101	6
Aurora B	100	10
BRSK1	91	3
BRSK2	90	9
BTK	98	7
CAMK1	116	9
CAMKK beta	4	1
CDK2-Cyclin A	83	3
CHK1	83	5
CHK2	47	11
CK1 delta	92	14
CK2	64	2
CLK2	71	1
CSK	86	0
DAPK1	54	1
DYRK1A	70	1
DYRK2	75	1
DYRK3	79	4
EF2K	69	1
EPH-A2	92	2
EPH-A4	97	3
EPH-B1	106	3
EPH-B2	112	14
EPH-B3	96	2
EPH-B4	90	0
ERK1	106	12
ERK2	85	3
ERK8	6	1
FGF-R1	107	9
GCK	62	5
GSK3 beta	73	5
HER4	100	4
HIPK1	100	1
HIPK2	88	11
HIPK3	89	7
IGF-1R	90	9
IKK beta	97	14
IKK epsilon	72	4
IR	58	10
IRAK4	107	11
IRR	63	2
JAK2	68	9
JNK1	98	5
JNK2	94	8
JNK3	66	4
Lck	98	4
LKB1	87	1
MAPKAP-K2	103	9
MAPKAP-K3	109	6
MARK1	108	3
MARK2	87	3
MARK3	92	6
MARK4	75	4
MEKK1	65	3
MELK	69	3
MINK1	71	15
MKK1	67	3
MKK2	111	6
MKK6	88	4
MLK1	73	2
MLK3	55	1
MNK1	10	2
MNK2	109	6
MSK1	95	4
MST2	89	1
MST4	91	2
NEK2a	84	1
NEK6	90	12
NUAK1	37	3
p38 alpha MAPK	93	7
p38 beta MAPK	86	12
p38 delta MAPK	115	4
p38 gamma MAPK	92	0
PAK2	103	3
PAK4	88	5
PAK5	113	8
PAK6	88	0
PDK1	95	4
PHK	108	8
PIM1	87	7
PIM2	61	4
PIM3	25	1
PKA	94	8
PKB alpha	90	3
PKB beta	91	9
PKC alpha	99	0
PKC zeta	88	9
PKD1	111	15
PLK1	96	1
PRAK	98	6
PRK2	89	7
RIPK2	93	3
ROCK 2	86	1
RSK1	95	3
RSK2	85	4
S6K1	86	0
SGK1	70	5
SmMLCK	93	6
Src	93	9
SRPK1	87	5
SYK	101	10
TAK1	85	10
TAO1	97	6
TBK1	61	8
TrkA	85	0
TTK	78	1
VEGFR1	98	2
YES1	97	5

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	30	1
ASK1	100	13
Aurora A	111	7
Aurora B	113	4
BRSK1	94	6
BRSK2	87	7
BTK	100	0
CAMK1	100	5
CAMKK beta	5	1
CDK2-Cyclin A	52	1
CHK1	97	13
CHK2	23	4
CK1 delta	81	3
CK2	15	1
CLK2	38	12
CSK	97	1
DAPK1	7	1
DYRK1A	18	1
DYRK2	32	1
DYRK3	36	0
EF2K	31	6
EPH-A2	102	11
EPH-A4	92	3
EPH-B1	122	1
EPH-B2	125	6
EPH-B3	95	2
EPH-B4	102	1
ERK1	108	8
ERK2	91	11
ERK8	2	0
FGF-R1	98	0
GCK	15	2
GSK3 beta	9	1
HER4	102	8
HIPK1	93	6
HIPK2	50	6
HIPK3	88	3
IGF-1R	72	6
IKK beta	97	14
IKK epsilon	28	8
IR	47	7
IRAK4	104	1
IRR	44	5
JAK2	52	4
JNK1	96	2
JNK2	95	8
JNK3	53	7
Lck	107	9
LKB1	91	4
MAPKAP-K2	107	4
MAPKAP-K3	103	9
MARK1	82	8
MARK2	110	1
MARK3	88	1
MARK4	74	1
MEKK1	36	1
MELK	76	4
MINK1	49	3
MKK1	46	1
MKK2	95	7
MKK6	88	6
MLK1	40	1
MLK3	16	3
MNK1	14	1
MNK2	92	5
MSK1	93	2
MST2	88	3
MST4	92	1
NEK2a	53	0
NEK6	104	11
NUAK1	33	8
p38 alpha MAPK	114	0
p38 beta MAPK	87	6
p38 delta MAPK	109	10
p38 gamma MAPK	96	3
PAK2	111	14
PAK4	84	1
PAK5	104	4
PAK6	92	8
PDK1	112	11
PHK	94	14
PIM1	39	6
PIM2	14	2
PIM3	25	2
PKA	100	4
PKB alpha	90	6
PKB beta	103	2
PKC alpha	84	8
PKC zeta	93	5
PKD1	105	7
PLK1	93	6
PRAK	102	1
PRK2	92	2
RIPK2	95	9
ROCK 2	112	4
RSK1	93	4
RSK2	106	6
S6K1	77	14
SGK1	60	15
SmMLCK	87	2
Src	112	1
SRPK1	77	4
SYK	95	15
TAK1	47	5
TAO1	87	8
TBK1	27	1
TrkA	90	4
TTK	60	1
VEGFR1	57	1
YES1	99	7