Inhibitor | SU-5416 (VEGFR2 Kinase Inhibitor III)  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
SU-5416 (VEGFR2 Kinase Inhibitor III)   C15H14N2O 238.30 204005-46-9 5329098 VEGF-R Tille J.C. (2003) Exp. Cell Res. 285 286 Itokawa T. (2002) Mol. Cancer Ther. 1 295

Screening Results Chart

Screening Results Tables

Screen Conc: 0.10µM
Kinase % Activity Remaining Standard Deviation
AMPK 85 5
ASK1 91 3
Aurora A 122 10
Aurora B 80 3
BRSK1 99 1
BRSK2 102 10
BTK 110 8
CAMK1 120 2
CAMKK beta 95 6
CDK2-Cyclin A 75 1
CHK1 95 11
CHK2 72 2
CK1 delta 92 3
CK2 88 4
CLK2 66 12
CSK 87 0
DAPK1 87 1
DYRK1A 108 8
DYRK2 97 1
DYRK3 93 1
EF2K 76 0
EPH-A2 105 14
EPH-A4 110 1
EPH-B1 117 14
EPH-B2 101 0
EPH-B3 108 10
EPH-B4 94 6
ERK1 81 3
ERK2 87 1
ERK8 106 1
FGF-R1 96 0
GCK 93 3
GSK3 beta 81 3
HER4 90 7
HIPK1 98 3
HIPK2 83 10
HIPK3 106 11
IGF-1R 88 6
IKK beta 97 3
IKK epsilon 99 6
IR 60 9
IRAK4 80 9
IRR 106 9
JAK2 84 1
JNK1 97 8
JNK2 99 3
JNK3 87 10
Lck 101 3
LKB1 86 1
MAPKAP-K2 115 5
MAPKAP-K3 94 2
MARK1 88 6
MARK2 93 5
MARK3 106 3
MARK4 100 2
MEKK1 73 8
MELK 86 1
MINK1 74 7
MKK1 79 4
MKK2 96 7
MKK6 108 0
MLK1 84 4
MLK3 49 3
MNK1 99 2
MNK2 96 3
MSK1 88 6
MST2 89 6
MST4 97 2
NEK2a 95 5
NEK6 103 11
NUAK1 79 8
p38 alpha MAPK 102 4
p38 beta MAPK 92 0
p38 delta MAPK 124 6
p38 gamma MAPK 93 0
PAK2 101 6
PAK4 102 7
PAK5 98 2
PAK6 93 2
PDK1 99 15
PHK 74 5
PIM1 104 11
PIM2 107 6
PIM3 92 8
PKA 90 4
PKB alpha 104 6
PKB beta 91 6
PKC alpha 102 2
PKC zeta 115 0
PKD1 90 8
PLK1 98 13
PRAK 96 8
PRK2 104 8
RIPK2 101 6
ROCK 2 103 7
RSK1 97 6
RSK2 91 3
S6K1 91 9
SGK1 107 3
SmMLCK 87 1
Src 96 2
SRPK1 109 0
SYK 102 6
TAK1 90 1
TAO1 76 12
TBK1 92 2
TrkA 29 3
TTK 100 15
VEGFR1 45 3
YES1 104 0
Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 65 10
ASK1 77 15
Aurora A 63 1
Aurora B 68 1
BRSK1 91 1
BRSK2 96 6
BTK 106 11
CAMK1 107 3
CAMKK beta 86 4
CDK2-Cyclin A 71 6
CHK1 85 2
CHK2 17 3
CK1 delta 56 4
CK2 99 10
CLK2 32 7
CSK 91 2
DAPK1 74 6
DYRK1A 86 4
DYRK2 106 2
DYRK3 88 3
EF2K 90 4
EPH-A2 109 11
EPH-A4 107 15
EPH-B1 100 14
EPH-B2 115 7
EPH-B3 112 4
EPH-B4 101 3
ERK1 89 10
ERK2 107 7
ERK8 105 12
FGF-R1 78 12
GCK 58 4
GSK3 beta 104 2
HER4 75 3
HIPK1 109 8
HIPK2 71 2
HIPK3 121 6
IGF-1R 52 3
IKK beta 89 12
IKK epsilon 72 5
IR 16 1
IRAK4 40 10
IRR 103 1
JAK2 60 11
JNK1 98 7
JNK2 104 10
JNK3 90 4
Lck 77 1
LKB1 83 8
MAPKAP-K2 110 5
MAPKAP-K3 86 7
MARK1 91 2
MARK2 97 6
MARK3 92 13
MARK4 77 1
MEKK1 25 4
MELK 69 5
MINK1 37 7
MKK1 50 2
MKK2 60 4
MKK6 122 1
MLK1 43 5
MLK3 18 0
MNK1 97 8
MNK2 112 5
MSK1 95 6
MST2 42 1
MST4 108 11
NEK2a 92 10
NEK6 108 5
NUAK1 40 6
p38 alpha MAPK 113 5
p38 beta MAPK 110 4
p38 delta MAPK 112 9
p38 gamma MAPK 98 4
PAK2 107 2
PAK4 122 11
PAK5 101 9
PAK6 119 4
PDK1 87 3
PHK 24 3
PIM1 74 3
PIM2 112 0
PIM3 95 2
PKA 107 13
PKB alpha 104 1
PKB beta 88 2
PKC alpha 126 6
PKC zeta 127 10
PKD1 93 15
PLK1 99 8
PRAK 114 7
PRK2 98 4
RIPK2 95 5
ROCK 2 100 5
RSK1 46 2
RSK2 72 1
S6K1 98 3
SGK1 94 6
SmMLCK 41 2
Src 103 4
SRPK1 105 5
SYK 110 3
TAK1 52 9
TAO1 93 0
TBK1 77 10
TrkA 25 4
TTK 89 10
VEGFR1 28 4
YES1 73 10
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 42 8
Aurora B
4
 1
CDK2-Cyclin A 91 5
CHK1 28 6
CHK2
6
 2
CK1 delta 21 3
CK2 80 8
CSK 95 5
DYRK1A 50 1
EF2K 79 1
ERK2 72 1
ERK8 54 3
GSK3 beta 84 4
IKK beta 99 6
JNK1 86 1
JNK3 75 1
Lck 26 5
MAPKAP-K3 80 6
MARK3 30 2
MKK1 22 1
MNK2 91 1
MST2
5
 0
NEK2a 54 0
NEK6 90 7
NEK7 88 3
p38 alpha MAPK 72 0
p38 beta MAPK 85 2
p38 delta MAPK 69 7
p38 gamma MAPK 78 2
PDK1 58 6
PHK
3
 0
PKB alpha 81 1
PKB beta 88 1
PLK1 84 7
PRAK 65 4
RSK1 11 3
RSK2 15 3
S6K1 19 1
SGK1 13 4
SmMLCK 22 4
Src 51 4
SRPK1 67 1