Services | MRC PPU International Centre for Kinase Profiling

We currently provide seven services:

  • MRC-PPU Premier Screen - Test your compounds against an extensive panel of 140 enzymes. This screen is undertaken once every 6 weeks and the data is provided 2 weeks from the screen start date.
  • MRC-PPU Express Screen - Compounds can be screened against a subset of 50 kinases representing all areas of the human kinome. This screen is undertaken once every 6 weeks and the data will be provided 1 week from the screen start date.
  • Lipid Kinase Screen - A panel of 16 lipid kinases undertaken once every 6 weeks with the data provided 1 week from the screen start date.
  • IC50 Determination - If you have a compound you know inhibits a kinase or would like to follow up on a hit from a previous screen you can submit it to determine the IC50 value.
  • ATP Competition Assay - Do you need to know if your compound of interest is a type I ATP competitive inhibitor?
  • Substrate Screen - Do you have a purified kinase but no substrate to assay its activity?
  • Custom Screening - Your compound(s) against your choice of kinase proteins available from our Premier Kinase Panel

To see the turnaround times and start dates of each screen please go to the Pricing and Turnaround page.