502

Compound name
Sotorasib
Alt Name
AMG-510
AMG510
Lumakras
Compound Image
Sotorasib.png
SMILES
CC1CN(CCN1C2=NC(=O)N(C3=NC(=C(C=C32)F)C4=C(C=CC=C4F)O)C5=C(C=CN=C5C(C)C)C)C(=O)C=C
MW
560.60
Brutto
C30H30F2N6O3
InChI
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
InChI Key
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Approval Jurisdiction
2021 FDA, 2022 EMA
Approved for clinical use
KRAS Non-Small-Cell Lung Cancer
CAS
2296729-00-3
PubChem CID
137278711
Approved Drug List
1