484

Compound name
Tepotinib
Alt Name
EMD-1214063
EMD 1214063
Compound Image
Tepotinib.png
SMILES
CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
MW
492.60
Brutto
C29H28N6O2
InChI
InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3
InChI Key
AHYMHWXQRWRBKT-UHFFFAOYSA-N
Approval Jurisdiction
2020 Japan 2021 FDA
Approved for clinical use
Metastatic NSCLC
CAS
1100598-32-0
PubChem CID
25171648
Action
MET ex 14 alterations
Approved Drug List
1
Commercial Vendor
EMD Serono