473

Compound name
Selumetinib
Alt Name
AZD6244
ARRY-142886
AZD 6244
Compound Image
Selumetinib.png
SMILES
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
MW
457.70
Brutto
C17H15BrClFN4O3
InChI
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChI Key
CYOHGALHFOKKQC-UHFFFAOYSA-N
Approval Jurisdiction
2020 FDA
Approved for clinical use
Neurofibromatosis Type 1
CAS
606143-52-6
PubChem CID
10127622
Action
MEK1/2
Approved Drug List
1
Commercial Vendor
Astra Zeneca