469

Compound name
Capmatinib
Alt Name
Tabrecta
INCB28060
INC280
Compound Image
Capmatinib_Tabrecta.png
SMILES
CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F
MW
412.40
Brutto
C23H17FN6O
InChI
InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)
InChI Key
LIOLIMKSCNQPLV-UHFFFAOYSA-N
Approval Jurisdiction
2020 FDA
Approved for clinical use
MET Mutation+Ve NSCLC
CAS
1029712-80-8
PubChem CID
25145656
Action
mutant MET
Approved Drug List
1
Commercial Vendor
Novartis