465

Compound name
Flumatinib
Alt Name
HH-GV678
HHGV678
flumbatinib
Compound Image
Flumatinib.png
SMILES
CC1=C(C=C(C=N1)NC(=O)C2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
MW
562.60
Brutto
C29H29F3N8O
InChI
InChI=1S/C29H29F3N8O/c1-19-26(38-28-34-9-7-25(37-28)21-4-3-8-33-16-21)15-23(17-35-19)36-27(41)20-5-6-22(24(14-20)29(30,31)32)18-40-12-10-39(2)11-13-40/h3-9,14-17H,10-13,18H2,1-2H3,(H,36,41)(H,34,37,38)
InChI Key
BJCJYEYYYGBROF-UHFFFAOYSA-N
Approval Jurisdiction
2019 China
Approved for clinical use
Chronic Myelogenous Leukemia
CAS
895519-90-1
PubChem CID
46848036
Action
Bcr-ABL; PDGFR
Approved Drug List
1
Commercial Vendor
Jiangsu Hansoh Pharmaceutical