460

Compound name
Fedratinib
Alt Name
Tg-101348
TG101348
SAR302503
Compound Image
Fedratinib.png
SMILES
CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
MW
524.70
Brutto
C27H36N6O3S
InChI
InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)
InChI Key
JOOXLOJCABQBSG-UHFFFAOYSA-N
Approval Jurisdiction
2019 FDA 2021EMA
Approved for clinical use
Myelofibrosis
CAS
936091-26-8
PubChem CID
16722836
Action
JAK3; FLT3; BRD4
Approved Drug List
1
Commercial Vendor
Celgene