447

Compound name
Duvelisib
Alt Name
IPI-145
INK-1197
Compound Image
Duvelisib.png
SMILES
CC(C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
MW
416.90
Brutto
C22H17ClN6O
InChI
InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
InChI Key
SJVQHLPISAIATJ-ZDUSSCGKSA-N
Approval Jurisdiction
2018 FDA
Approved for clinical use
CLL, SLL, FL
CAS
1201438-56-3
PubChem CID
50905713
Action
PI3K δ/ γ
Approved Drug List
1
Commercial Vendor
Verastem Oncology