392

Compound name
Ponatinib
Alt Name
Iclusig
AP24534
Compound Image
Ponatinib.png
SMILES
CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Brutto
C29H27F3N6O
InChI
InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)
InChI Key
PHXJVRSECIGDHY-UHFFFAOYSA-N
Approval Jurisdiction
2012 FDA
Approved for clinical use
Chronic Myelogenous Leukemia, ALL
CAS
943319-70-8
PubChem CID
24826799
Action
SRC, Ab1
Approved Drug List
1
Commercial Vendor
Ariad