387

Compound name
Crizotinib
Alt Name
Xalkori
Crizonix
Compound Image
Crizotinib.png
SMILES
CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
Brutto
C21H22Cl2FN5O
InChI
InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
InChI Key
KTEIFNKAUNYNJU-GFCCVEGCSA-N
Approval Jurisdiction
2011 FDA
Approved for clinical use
NSCLC With Alkmutation
CAS
877399-52-5
PubChem CID
11626560
Action
ALK, MET
Approved Drug List
1
Commercial Vendor
Pfizer