Compound name
Sorafenib
Alt Name
Sorafenib
Kinome_766
AC1L50CF
CHEMBL1336
BAY-439006
BAY 439006
BAY439006
Nexavar
Compound Image
Sorafenib.png
SMILES
CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
MW
464.80
Brutto
C21H16ClF3N4O3
InChI
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChI Key
MLDQJTXFUGDVEO-UHFFFAOYSA-N
Approval Jurisdiction
2005 FDA, 2006 EMA
Approved for clinical use
Renal Cancer HCC
CAS
284461-73-0
PubChem CID
216239
Action
Raf, Multiple Tyrosine Kinases Targeted
Approved Drug List
1
Patent
<a href="http://www.wipo.int/patentscope/search/en/result.jsf?query=ALLNUM%3AWO2002085857">WO2002085857</a>
Commercial Vendor
Onyx/Bayer
Reference 2