Inhibitor | Rottlerin  

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	93	4
Aurora B	45	0
Aurora C	50	3
BRSK2	94	6
CAMK1	93	7
CAMKK beta	42	8
CDK2-Cyclin A	93	9
CHK1	105	6
CHK2	11	2
CK1 delta	83	6
CK2	91	8
CSK	99	12
DYRK1A	96	5
DYRK2	96	2
DYRK3	31	4
EF2K	92	11
EPH-A2	71	11
ERK1	96	6
ERK2	77	10
ERK8	77	3
FGF-R1	57	0
GSK3 beta	94	11
HIPK2	80	12
HIPK3	93	6
IKK beta	77	0
IKK epsilon	71	12
IRR	101	9
JNK1	80	5
JNK2	84	6
JNK3	74	0
Lck	84	14
MAPKAP-K2	34	12
MAPKAP-K3	82	5
MARK3	94	2
MELK	60	4
MKK1	74	7
MNK1	77	0
MNK2	84	3
MSK1	75	1
MST2	73	6
MST4	87	9
NEK2a	104	5
NEK6	96	12
NEK7	96	9
p38 alpha MAPK	93	1
p38 beta MAPK	118	7
p38 delta MAPK	86	7
p38 gamma MAPK	94	4
PAK4	53	7
PAK5	84	0
PAK6	120	8
PDK1	80	1
PHK	74	6
PIM1	63	3
PIM2	93	3
PIM3	14	0
PKA	64	11
PKB alpha	76	3
PKB beta	48	0
PKC alpha	59	7
PKC zeta	107	10
PKD1	79	7
PLK1	40	11
PRAK	41	9
PRK2	83	4
ROCK 2	91	5
RSK1	74	5
RSK2	52	5
S6K1	85	3
SGK1	72	7
SmMLCK	24	9
Src	63	7
SRPK1	6	2
SYK	66	0
TBK1	82	1
YES1	42	5

Screen Conc: 20.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	54	2
Aurora B	51	3
Aurora C	42	4
BRSK2	25	7
CAMK1	37	1
CAMKK alpha	55	2
CAMKK beta	27	3
CDK2-Cyclin A	87	2
CHK1	133	1
CHK2	6	0
CK1 delta	94	8
CK2	91	1
CSK	73	3
DYRK1A	13	2
DYRK2	16	6
DYRK3	5	0
EF2K	74	7
ERK1	105	1
ERK2	97	2
ERK8	91	2
GSK3 beta	33	3
HIPK2	72	8
HIPK3	79	8
IKK beta	13	2
JNK1	22	4
JNK2	69	0
JNK3	52	0
Lck	77	4
MAPKAP-K2	8	4
MAPKAP-K3	4	0
MARK3	102	0
MELK	38	4
MKK1	82	8
MNK1	75	0
MNK2	100	4
MSK1	53	1
MST2	51	3
NEK2a	89	2
NEK6	87	4
NEK7	110	2
p38 alpha MAPK	118	0
p38 beta MAPK	127	1
p38 delta MAPK	80	1
p38 gamma MAPK	122	1
PAK4	19	1
PAK5	65	0
PAK6	67	5
PDK1	62	5
PHK	72	2
PIM1	23	1
PIM2	68	3
PIM3	3	0
PKA	3	1
PKB alpha	93	5
PKB beta	11	5
PKC alpha	64	0
PKC zeta	92	3
PKD1	63	3
PLK1	20	8
PRAK	0	0
PRK2	93	1
ROCK 2	75	1
RSK1	16	2
RSK2	23	1
S6K1	33	0
SGK1	22	5
SmMLCK	15	3
Src	97	8
SRPK1	9	1