Inhibitor | Roscovitine  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	91	2
Aurora B	94	6
Aurora C	96	4
BRSK2	79	4
CAMK1	104	3
CAMKK alpha	73	5
CAMKK beta	71	5
CDK2-Cyclin A	4	0
CHK1	87	5
CHK2	93	4
CK1 delta	76	1
CK2	92	7
CSK	88	4
DYRK1A	87	5
DYRK2	90	4
DYRK3	97	2
EF2K	85	8
ERK1	82	2
ERK2	83	2
ERK8	40	5
GSK3 beta	76	6
HIPK2	84	5
HIPK3	90	1
IKK beta	80	3
JNK1	89	5
JNK2	88	6
JNK3	87	2
Lck	76	2
MAPKAP-K2	97	7
MAPKAP-K3	86	5
MARK3	87	5
MELK	88	7
MKK1	81	5
MNK1	90	8
MNK2	97	2
MSK1	78	1
MST2	95	5
NEK2a	85	6
NEK6	92	4
NEK7	87	5
p38 alpha MAPK	96	4
p38 beta MAPK	94	3
p38 delta MAPK	92	7
p38 gamma MAPK	99	2
PAK4	90	3
PAK5	74	3
PAK6	80	2
PDK1	80	8
PHK	93	1
PIM1	83	5
PIM2	106	4
PIM3	83	9
PKA	73	1
PKB alpha	100	3
PKB beta	83	4
PKC alpha	89	2
PKC zeta	82	6
PKD1	90	4
PLK1	91	1
PRAK	83	4
PRK2	89	2
ROCK 2	90	4
RSK1	97	2
RSK2	71	3
S6K1	90	5
SGK1	75	2
SmMLCK	84	3
Src	89	2
SRPK1	84	4

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	109	4
Aurora B	110	8
BRSK2	103	24
BTK	90	9
CAMK1	96	5
CAMKK beta	46	0
CDK2-Cyclin A	3	1
CHK1	103	9
CHK2	67	15
CK1 delta	30	1
CK2	102	0
CSK	103	5
DYRK1A	13	0
DYRK2	81	4
DYRK3	99	2
EF2K	111	4
EPH-A2	97	3
EPH-B3	91	7
ERK1	60	9
ERK2	41	7
ERK8	11	4
FGF-R1	96	6
GSK3 beta	102	1
HIPK2	99	9
IGF-1R	60	5
IKK beta	100	14
IKK epsilon	104	2
IR	42	3
IRR	40	0
JNK1	104	19
JNK2	105	1
Lck	125	5
MAPKAP-K2	106	7
MARK3	102	0
MELK	70	11
MKK1	61	1
MNK1	105	21
MNK2	109	10
MSK1	115	0
MST2	103	7
MST4	100	3
NEK2a	96	2
NEK6	105	5
p38 alpha MAPK	92	2
p38 beta MAPK	106	4
p38 delta MAPK	88	14
p38 gamma MAPK	109	0
PAK4	40	2
PAK5	56	5
PAK6	84	2
PDK1	116	14
PHK	99	8
PIM1	103	4
PIM2	99	5
PIM3	103	3
PKA	102	4
PKB alpha	111	14
PKB beta	98	3
PKC alpha	160	53
PKC zeta	89	7
PKD1	103	3
PLK1	73	4
PRAK	102	2
PRK2	110	8
ROCK 2	110	8
RSK1	66	5
RSK2	98	16
S6K1	125	2
SGK1	92	4
SmMLCK	78	1
Src	97	6
SRPK1	51	1
SYK	113	6
TBK1	97	7
VEGFR1	95	4
YES1	103	12