Inhibitor | PP1  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	99	7
BRSK2	93	15
BTK	12	4
CAMK1	102	3
CAMKK beta	84	4
CDK2-Cyclin A	105	6
CHK1	90	4
CHK2	117	12
CK1 delta	75	1
CK2	107	1
CSK	68	1
DYRK1A	88	3
DYRK2	91	8
DYRK3	98	12
EF2K	97	18
EPH-A2	40	0
EPH-B3	30	8
ERK1	82	0
ERK2	103	2
ERK8	88	2
FGF-R1	68	11
GSK3 beta	94	2
HIPK2	99	5
IGF-1R	102	8
IKK beta	89	4
IKK epsilon	98	13
IR	96	6
IRR	77	13
JNK1	95	11
JNK2	88	1
Lck	33	0
MAPKAP-K2	78	2
MARK3	93	5
MELK	87	0
MKK1	85	3
MNK1	93	3
MNK2	94	7
MSK1	92	10
MST2	82	6
MST4	99	3
NEK2a	100	8
NEK6	88	5
p38 alpha MAPK	78	3
p38 beta MAPK	89	4
p38 delta MAPK	84	9
p38 gamma MAPK	102	0
PAK4	89	3
PAK5	98	17
PAK6	97	0
PDK1	99	11
PHK	90	12
PIM1	98	11
PIM2	103	5
PIM3	88	13
PKA	86	2
PKB alpha	95	1
PKB beta	127	42
PKC alpha	95	15
PKC zeta	89	6
PKD1	89	9
PLK1	88	6
PRAK	102	11
PRK2	108	4
ROCK 2	86	2
RSK1	94	16
RSK2	91	6
S6K1	86	14
SGK1	87	3
SmMLCK	103	23
Src	17	0
SRPK1	105	9
SYK	96	5
TBK1	78	0
VEGFR1	67	5
YES1	10	0

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	102	9
Aurora B	73	1
Aurora C	47	5
BRSK2	90	8
BTK	3	0
CAMK1	90	3
CAMKK alpha	91	16
CAMKK beta	96	3
CDK2-Cyclin A	89	6
CHK1	90	6
CHK2	101	6
CK1 delta	20	2
CK2	99	4
CSK	39	1
DYRK1A	97	6
DYRK2	85	1
DYRK3	92	2
EF2K	127	7
EPH-A2	11	2
EPH-B3	6	4
ERK1	113	1
ERK2	94	2
ERK8	94	2
FGF-R1	19	1
GSK3 beta	94	6
HIPK2	86	8
HIPK3	101	3
IGF-1R	106	4
IKK beta	79	14
IKK epsilon	72	2
IR	103	2
IRR	67	20
JNK1	93	10
JNK2	85	4
JNK3	85	0
Lck	6	1
MAPKAP-K2	101	1
MAPKAP-K3	98	3
MARK3	128	5
MELK	58	1
MKK1	67	5
MNK1	76	1
MNK2	97	1
MSK1	72	12
MST2	70	3
MST4	78	5
NEK2a	85	1
NEK6	80	3
NEK7	116	2
p38 alpha MAPK	43	2
p38 beta MAPK	38	2
p38 delta MAPK	69	7
p38 gamma MAPK	98	8
PAK4	92	7
PAK5	87	3
PAK6	96	2
PDK1	84	11
PHK	85	7
PIM1	89	8
PIM2	111	15
PIM3	91	10
PKA	52	3
PKB alpha	95	0
PKB beta	97	11
PKC alpha	75	4
PKC zeta	93	7
PKD1	76	2
PLK1	83	6
PRAK	101	0
PRK2	84	3
ROCK 2	81	0
RSK1	94	4
RSK2	99	1
S6K1	42	5
SGK1	87	0
SmMLCK	92	9
Src	4	1
SRPK1	93	4
SYK	92	12
TBK1	60	6
VEGFR1	16	0
YES1	1	0

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	107	1
Aurora B	40	1
Aurora C	17	1
BRSK2	2	0
CAMK1	87	2
CAMKK alpha	71	4
CAMKK beta	52	2
CDK2-Cyclin A	58	0
CHK1	95	1
CHK2	55	4
CK1 delta	4	0
CK2	100	7
CSK	4	0
DYRK1A	81	7
DYRK2	94	2
DYRK3	61	2
EF2K	100	0
ERK1	104	6
ERK2	75	0
ERK8	73	8
GSK3 beta	100	1
HIPK2	65	0
HIPK3	102	4
IKK beta	85	1
JNK1	92	0
JNK2	42	2
JNK3	50	0
Lck	2	0
MAPKAP-K2	107	6
MAPKAP-K3	114	4
MARK3	93	1
MELK	23	4
MKK1	59	1
MNK1	50	6
MNK2	74	2
MSK1	45	1
MST2	34	2
NEK2a	84	3
NEK6	111	8
NEK7	107	2
p38 alpha MAPK	11	2
p38 beta MAPK	10	1
p38 delta MAPK	87	8
p38 gamma MAPK	88	1
PAK4	63	2
PAK5	71	3
PAK6	90	0
PDK1	82	5
PHK	67	1
PIM1	97	1
PIM2	89	7
PIM3	79	2
PKA	29	0
PKB alpha	79	6
PKB beta	93	8
PKC alpha	52	2
PKC zeta	77	2
PKD1	41	9
PLK1	92	8
PRAK	77	8
PRK2	81	7
ROCK 2	43	3
RSK1	49	6
RSK2	69	5
S6K1	15	0
SGK1	84	0
SmMLCK	76	0
Src	0	0
SRPK1	82	5