Inhibitor | Pirfenidone  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	106	5
AMPK	99	5
ASK1	114	25
Aurora A	106	4
Aurora B	93	5
BRK	101	5
BRSK1	95	10
BRSK2	106	0
BTK	119	4
CAMK1	98	3
CAMKK beta	97	1
CDK2-Cyclin A	103	5
CHK1	97	8
CHK2	119	7
CK1 delta	97	12
CK2	98	0
CLK2	120	16
CSK	98	1
DAPK1	112	3
DYRK1A	103	1
DYRK2	107	2
DYRK3	103	9
EF2K	83	2
EIF2AK3	106	9
EPH-A2	113	11
EPH-A4	106	9
EPH-B1	109	22
EPH-B2	120	19
EPH-B3	96	5
EPH-B4	112	9
ERK1	125	13
ERK2	95	4
ERK8	95	8
FGF-R1	101	8
GCK	106	9
GSK3 beta	102	2
HER4	123	23
HIPK1	118	3
HIPK2	122	2
HIPK3	100	12
IGF-1R	105	5
IKK beta	87	10
IKK epsilon	104	7
IR	110	4
IRAK1	105	6
IRAK4	83	4
IRR	104	3
JAK2	103	7
JNK1	85	2
JNK2	85	12
JNK3	83	1
Lck	96	18
LKB1	103	16
MAPKAP-K2	108	5
MAPKAP-K3	92	4
MARK1	99	16
MARK2	104	7
MARK3	108	0
MARK4	98	25
MEKK1	106	6
MELK	94	4
MINK1	106	1
MKK1	77	0
MKK2	58	4
MKK6	106	5
MLK1	95	12
MLK3	108	16
MNK1	101	12
MNK2	90	2
MPSK1	87	0
MSK1	98	5
MST2	112	15
MST4	105	6
NEK2a	107	9
NEK6	99	2
NUAK1	115	1
OSR1	114	20
p38 alpha MAPK	102	10
p38 beta MAPK	120	11
p38 delta MAPK	97	10
p38 gamma MAPK	109	3
PAK2	101	7
PAK4	101	8
PAK5	88	4
PAK6	106	8
PDK1	97	9
PHK	103	0
PIM1	105	9
PIM2	118	8
PIM3	111	5
PKA	90	10
PKB alpha	108	11
PKB beta	99	11
PKC alpha	99	20
PKC gamma	99	11
PKC zeta	109	5
PKD1	122	12
PLK1	96	1
PRAK	100	2
PRK2	121	9
RIPK2	86	11
ROCK 2	94	8
RSK1	107	4
RSK2	98	2
S6K1	115	10
SGK1	113	4
SmMLCK	102	8
Src	123	11
SRPK1	95	9
STK33	82	9
SYK	99	17
TAK1	103	21
TAO1	118	4
TBK1	99	14
TESK1	94	6
TIE2	110	4
TLK1	113	6
TrkA	103	14
TSSK1	87	11
TTBK1	124	0
TTK	73	11
VEGFR1	100	13
YES1	118	8
ZAP70	110	1

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	112	15
AMPK	103	2
ASK1	99	3
Aurora A	107	2
Aurora B	87	0
BRK	92	16
BRSK1	93	4
BRSK2	96	3
BTK	115	10
CAMK1	81	1
CAMKK beta	108	2
CDK2-Cyclin A	97	0
CHK1	90	2
CHK2	97	0
CK1 delta	102	13
CK2	103	4
CLK2	112	7
CSK	87	1
DAPK1	100	16
DYRK1A	91	15
DYRK2	98	3
DYRK3	93	5
EF2K	87	6
EIF2AK3	105	3
EPH-A2	111	3
EPH-A4	99	9
EPH-B1	104	2
EPH-B2	109	3
EPH-B3	112	15
EPH-B4	120	8
ERK1	115	6
ERK2	97	1
ERK8	86	13
FGF-R1	104	22
GCK	108	0
GSK3 beta	99	0
HER4	106	19
HIPK1	103	4
HIPK2	106	14
HIPK3	96	6
IGF-1R	102	1
IKK beta	88	6
IKK epsilon	99	2
IR	103	3
IRAK1	93	27
IRAK4	95	0
IRR	99	7
JAK2	90	10
JNK1	87	3
JNK2	86	1
JNK3	86	11
Lck	102	12
LKB1	95	14
MAPKAP-K2	93	2
MAPKAP-K3	84	9
MARK1	98	6
MARK2	102	1
MARK3	108	3
MARK4	74	3
MEKK1	103	0
MELK	98	10
MINK1	108	3
MKK1	65	10
MKK2	35	8
MKK6	88	7
MLK1	89	8
MLK3	98	5
MNK1	99	0
MNK2	93	7
MPSK1	96	6
MSK1	95	3
MST2	112	10
MST4	102	2
NEK2a	95	8
NEK6	91	9
NUAK1	100	6
OSR1	115	8
p38 alpha MAPK	83	7
p38 beta MAPK	111	1
p38 delta MAPK	91	2
p38 gamma MAPK	96	8
PAK2	100	6
PAK4	89	4
PAK5	96	2
PAK6	96	3
PDK1	95	3
PHK	96	6
PIM1	106	12
PIM2	96	7
PIM3	95	8
PKA	97	7
PKB alpha	102	12
PKB beta	91	8
PKC alpha	118	9
PKC gamma	94	8
PKC zeta	97	13
PKD1	91	6
PLK1	82	9
PRAK	95	7
PRK2	91	1
RIPK2	87	7
ROCK 2	84	6
RSK1	114	1
RSK2	94	0
S6K1	111	7
SGK1	100	4
SmMLCK	89	0
Src	102	5
SRPK1	89	8
STK33	90	4
SYK	103	9
TAK1	119	35
TAO1	100	5
TBK1	91	0
TESK1	82	8
TIE2	118	18
TLK1	115	1
TrkA	112	3
TSSK1	91	16
TTBK1	107	15
TTK	76	7
VEGFR1	107	15
YES1	109	2
ZAP70	100	21