Inhibitor | PI-103  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	105	15
Aurora B	83	1
Aurora C	103	3
BRSK2	96	0
CAMK1	108	7
CAMKK alpha	88	7
CAMKK beta	79	5
CDK2-Cyclin A	95	5
CHK1	94	5
CHK2	78	11
CK1 delta	87	1
CK2	82	6
CSK	82	0
DYRK1A	87	5
DYRK2	81	7
DYRK3	79	8
EF2K	110	13
ERK1	88	6
ERK2	96	4
ERK8	74	3
GSK3 beta	84	10
HIPK2	67	0
HIPK3	75	6
IKK beta	95	4
JNK1	97	3
JNK2	93	4
JNK3	90	6
Lck	89	2
MAPKAP-K2	99	17
MAPKAP-K3	88	15
MARK3	99	6
MELK	79	8
MKK1	68	5
MNK1	89	6
MNK2	103	11
MSK1	96	1
MST2	91	5
NEK2a	114	2
NEK6	111	6
NEK7	106	1
p38 alpha MAPK	91	5
p38 beta MAPK	85	5
p38 delta MAPK	81	4
p38 gamma MAPK	97	8
PAK4	97	4
PAK5	90	8
PAK6	98	7
PDK1	90	1
PHK	83	5
PIM1	77	2
PIM2	106	7
PIM3	79	2
PKA	73	6
PKB alpha	74	2
PKB beta	76	5
PKC alpha	82	4
PKC zeta	76	2
PKD1	92	2
PLK1	79	10
PRAK	92	6
PRK2	80	8
ROCK 2	75	3
RSK1	90	13
RSK2	104	9
S6K1	81	7
SGK1	88	2
SmMLCK	62	5
Src	90	7
SRPK1	82	8

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	88	0
Aurora B	81	1
Aurora C	73	4
BRSK2	63	1
CAMK1	73	1
CAMKK alpha	78	5
CAMKK beta	72	1
CDK2-Cyclin A	70	1
CHK1	85	0
CHK2	97	0
CK1 delta	68	0
CK2	77	2
CSK	74	2
DYRK1A	64	1
DYRK2	72	1
DYRK3	21	4
EF2K	108	4
ERK1	114	5
ERK2	90	4
ERK8	45	6
GSK3 beta	48	4
HIPK2	60	0
HIPK3	68	0
IKK beta	79	0
JNK1	95	7
JNK2	81	6
JNK3	87	0
Lck	62	1
MAPKAP-K2	110	5
MAPKAP-K3	97	7
MARK3	77	2
MELK	55	2
MKK1	69	3
MNK1	71	6
MNK2	84	1
MSK1	83	1
MST2	73	5
NEK2a	77	9
NEK6	83	0
NEK7	104	4
p38 alpha MAPK	86	0
p38 beta MAPK	97	3
p38 delta MAPK	87	0
p38 gamma MAPK	99	2
PAK4	75	5
PAK5	86	3
PAK6	97	0
PDK1	91	1
PHK	56	4
PIM1	60	8
PIM2	77	4
PIM3	27	8
PKA	77	1
PKB alpha	65	0
PKB beta	79	2
PKC alpha	53	0
PKC zeta	79	4
PKD1	87	7
PLK1	86	1
PRAK	79	4
PRK2	55	4
ROCK 2	87	5
RSK1	41	0
RSK2	51	5
S6K1	86	2
SGK1	79	4
SmMLCK	18	5
Src	82	8
SRPK1	78	2