Inhibitor | PD 0325901-Cl (CI-1055-S)  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
PD 0325901-Cl (CI-1055-S)   C16H14O4N2F2ClI 498.65 391210-10-9 160968186 MEK1

Screening Results Chart

Screening Results Tables

Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
MKK1
3
 2
JAK2
8
 0
MKK2 14 5
MKK6 61 15
PIM1 62 3
PIM3 68 5
MLK1 74 8
MARK3 75 4
PAK4 80 7
Src 80 11
RIPK2 81 8
MAPKAP-K3 81 14
IGF-1R 81 8
TTK 82 1
PAK2 83 11
MARK1 83 3
PKC alpha 83 7
OSR1 84 1
MPSK1 84 13
SmMLCK 84 15
PRK2 84 1
IRAK1 84 1
Aurora B 86 1
JNK3 86 1
PAK5 87 1
PIM2 88 7
TrkA 88 13
CK1 delta 88 6
CLK2 88 0
CSK 89 5
EPH-B4 90 11
JNK2 90 4
ZAP70 90 8
PKD1 90 9
CDK2-Cyclin A 90 2
ERK8 90 15
NEK6 91 6
ERK2 91 2
YES1 91 5
SYK 91 13
MNK1 92 11
PKB beta 92 1
MARK4 92 13
JNK1 92 1
IRR 92 11
p38 gamma MAPK 92 2
IRAK4 92 5
EPH-B3 93 3
NUAK1 93 5
PKC zeta 93 4
EPH-B1 94 10
AMPK 94 1
PRAK 94 1
FGF-R1 94 7
BRSK1 94 2
TIE2 94 1
RSK2 95 7
ERK1 95 13
CAMK1 95 1
PKC gamma 95 12
DYRK1A 95 10
HIPK3 95 6
DYRK3 96 14
MST2 96 10
DAPK1 96 1
EF2K 96 14
IR 97 21
MELK 97 7
GSK3 beta 97 6
EPH-A4 98 4
PDK1 98 6
PAK6 98 12
TBK1 98 10
Lck 98 10
CHK2 98 4
VEGFR1 98 4
TLK1 99 12
HIPK1 99 14
PHK 100 5
MLK3 100 2
MNK2 101 6
MAPKAP-K2 101 2
IKK beta 101 10
IKK epsilon 101 8
MEKK1 101 4
BTK 101 2
ASK1 101 2
HIPK2 101 13
TAK1 101 2
p38 delta MAPK 101 12
EPH-A2 101 6
ROCK 2 102 4
BRSK2 102 12
p38 alpha MAPK 102 5
STK33 102 4
MARK2 103 8
MST4 103 11
SRPK1 103 0
CK2 103 20
DYRK2 103 13
PKB alpha 104 2
GCK 104 5
PLK1 104 5
NEK2a 105 4
Aurora A 106 6
EIF2AK3 107 1
SGK1 108 5
CAMKK beta 108 2
ABL 108 0
S6K1 110 21
PKA 110 0
EPH-B2 111 3
TAO1 111 13
LKB1 112 3
BRK 112 10
MSK1 112 5
RSK1 115 5
CHK1 115 22
MINK1 117 12
HER4 121 0
p38 beta MAPK 129 5
Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
JAK2
8
 1
MKK1 20 5
MKK2 48 1
JNK3 73 3
ROCK 2 77 5
PKD1 78 5
SmMLCK 81 8
HIPK3 82 12
PRAK 82 4
MKK6 82 1
p38 gamma MAPK 83 9
MLK1 84 6
MSK1 84 3
MPSK1 84 0
PKA 84 11
SRPK1 85 6
CHK2 85 6
PKB beta 85 0
MARK1 86 12
CSK 86 5
BRSK1 86 7
CLK2 87 6
RIPK2 87 7
PAK4 87 11
MAPKAP-K2 87 1
TBK1 88 0
IGF-1R 88 9
MEKK1 88 5
PRK2 89 1
PKC alpha 89 12
PAK6 89 4
ABL 89 0
JNK2 90 10
VEGFR1 90 1
CK1 delta 90 12
EPH-A2 90 10
PDK1 90 13
NEK6 90 10
PIM1 90 9
CHK1 91 15
MELK 91 14
TrkA 91 9
NUAK1 91 5
JNK1 91 4
DAPK1 92 4
EF2K 92 15
CDK2-Cyclin A 92 8
TIE2 92 1
MNK1 92 4
PAK2 92 2
RSK2 92 1
TLK1 92 10
NEK2a 92 8
AMPK 92 5
IKK beta 92 10
CAMKK beta 92 2
GSK3 beta 93 12
p38 delta MAPK 93 5
IRAK4 93 9
DYRK3 93 9
MST4 93 2
MARK4 93 5
IRR 94 8
PKC gamma 94 10
HIPK2 94 4
DYRK1A 94 11
DYRK2 94 4
Aurora B 94 1
MNK2 94 5
Src 94 1
SGK1 94 2
FGF-R1 94 9
ERK2 94 2
IRAK1 95 5
IKK epsilon 95 8
EPH-B4 95 7
Lck 95 3
PHK 95 9
PKC zeta 96 7
ERK8 96 11
TTK 96 10
MST2 96 0
CAMK1 96 7
YES1 96 4
p38 alpha MAPK 97 13
TAO1 97 14
MARK2 97 14
GCK 97 1
HER4 97 5
MLK3 98 7
ASK1 98 7
OSR1 98 10
MAPKAP-K3 98 1
ERK1 98 13
MINK1 98 9
PIM3 98 4
ZAP70 99 10
Aurora A 99 10
PKB alpha 99 8
CK2 100 12
EPH-A4 100 3
MARK3 100 10
PIM2 100 7
TAK1 102 11
STK33 102 4
PAK5 102 5
RSK1 103 7
EPH-B1 103 7
BTK 104 9
PLK1 104 6
LKB1 104 3
IR 104 2
BRK 106 3
S6K1 106 3
EPH-B3 108 2
EIF2AK3 109 9
HIPK1 109 7
p38 beta MAPK 110 11
BRSK2 111 5
SYK 114 8
EPH-B2 121 2