Inhibitor | PD 0325901-Cl (CI-1055-S)  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	89	0
AMPK	92	5
ASK1	98	7
Aurora A	99	10
Aurora B	94	1
BRK	106	3
BRSK1	86	7
BRSK2	111	5
BTK	104	9
CAMK1	96	7
CAMKK beta	92	2
CDK2-Cyclin A	92	8
CHK1	91	15
CHK2	85	6
CK1 delta	90	12
CK2	100	12
CLK2	87	6
CSK	86	5
DAPK1	92	4
DYRK1A	94	11
DYRK2	94	4
DYRK3	93	9
EF2K	92	15
EIF2AK3	109	9
EPH-A2	90	10
EPH-A4	100	3
EPH-B1	103	7
EPH-B2	121	2
EPH-B3	108	2
EPH-B4	95	7
ERK1	98	13
ERK2	94	2
ERK8	96	11
FGF-R1	94	9
GCK	97	1
GSK3 beta	93	12
HER4	97	5
HIPK1	109	7
HIPK2	94	4
HIPK3	82	12
IGF-1R	88	9
IKK beta	92	10
IKK epsilon	95	8
IR	104	2
IRAK1	95	5
IRAK4	93	9
IRR	94	8
JAK2	8	1
JNK1	91	4
JNK2	90	10
JNK3	73	3
Lck	95	3
LKB1	104	3
MAPKAP-K2	87	1
MAPKAP-K3	98	1
MARK1	86	12
MARK2	97	14
MARK3	100	10
MARK4	93	5
MEKK1	88	5
MELK	91	14
MINK1	98	9
MKK1	20	5
MKK2	48	1
MKK6	82	1
MLK1	84	6
MLK3	98	7
MNK1	92	4
MNK2	94	5
MPSK1	84	0
MSK1	84	3
MST2	96	0
MST4	93	2
NEK2a	92	8
NEK6	90	10
NUAK1	91	5
OSR1	98	10
p38 alpha MAPK	97	13
p38 beta MAPK	110	11
p38 delta MAPK	93	5
p38 gamma MAPK	83	9
PAK2	92	2
PAK4	87	11
PAK5	102	5
PAK6	89	4
PDK1	90	13
PHK	95	9
PIM1	90	9
PIM2	100	7
PIM3	98	4
PKA	84	11
PKB alpha	99	8
PKB beta	85	0
PKC alpha	89	12
PKC gamma	94	10
PKC zeta	96	7
PKD1	78	5
PLK1	104	6
PRAK	82	4
PRK2	89	1
RIPK2	87	7
ROCK 2	77	5
RSK1	103	7
RSK2	92	1
S6K1	106	3
SGK1	94	2
SmMLCK	81	8
Src	94	1
SRPK1	85	6
STK33	102	4
SYK	114	8
TAK1	102	11
TAO1	97	14
TBK1	88	0
TIE2	92	1
TLK1	92	10
TrkA	91	9
TTK	96	10
VEGFR1	90	1
YES1	96	4
ZAP70	99	10

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	108	0
AMPK	94	1
ASK1	101	2
Aurora A	106	6
Aurora B	86	1
BRK	112	10
BRSK1	94	2
BRSK2	102	12
BTK	101	2
CAMK1	95	1
CAMKK beta	108	2
CDK2-Cyclin A	90	2
CHK1	115	22
CHK2	98	4
CK1 delta	88	6
CK2	103	20
CLK2	88	0
CSK	89	5
DAPK1	96	1
DYRK1A	95	10
DYRK2	103	13
DYRK3	96	14
EF2K	96	14
EIF2AK3	107	1
EPH-A2	101	6
EPH-A4	98	4
EPH-B1	94	10
EPH-B2	111	3
EPH-B3	93	3
EPH-B4	90	11
ERK1	95	13
ERK2	91	2
ERK8	90	15
FGF-R1	94	7
GCK	104	5
GSK3 beta	97	6
HER4	121	0
HIPK1	99	14
HIPK2	101	13
HIPK3	95	6
IGF-1R	81	8
IKK beta	101	10
IKK epsilon	101	8
IR	97	21
IRAK1	84	1
IRAK4	92	5
IRR	92	11
JAK2	8	0
JNK1	92	1
JNK2	90	4
JNK3	86	1
Lck	98	10
LKB1	112	3
MAPKAP-K2	101	2
MAPKAP-K3	81	14
MARK1	83	3
MARK2	103	8
MARK3	75	4
MARK4	92	13
MEKK1	101	4
MELK	97	7
MINK1	117	12
MKK1	3	2
MKK2	14	5
MKK6	61	15
MLK1	74	8
MLK3	100	2
MNK1	92	11
MNK2	101	6
MPSK1	84	13
MSK1	112	5
MST2	96	10
MST4	103	11
NEK2a	105	4
NEK6	91	6
NUAK1	93	5
OSR1	84	1
p38 alpha MAPK	102	5
p38 beta MAPK	129	5
p38 delta MAPK	101	12
p38 gamma MAPK	92	2
PAK2	83	11
PAK4	80	7
PAK5	87	1
PAK6	98	12
PDK1	98	6
PHK	100	5
PIM1	62	3
PIM2	88	7
PIM3	68	5
PKA	110	0
PKB alpha	104	2
PKB beta	92	1
PKC alpha	83	7
PKC gamma	95	12
PKC zeta	93	4
PKD1	90	9
PLK1	104	5
PRAK	94	1
PRK2	84	1
RIPK2	81	8
ROCK 2	102	4
RSK1	115	5
RSK2	95	7
S6K1	110	21
SGK1	108	5
SmMLCK	84	15
Src	80	11
SRPK1	103	0
STK33	102	4
SYK	91	13
TAK1	101	2
TAO1	111	13
TBK1	98	10
TIE2	94	1
TLK1	99	12
TrkA	88	13
TTK	82	1
VEGFR1	98	4
YES1	91	5
ZAP70	90	8