Inhibitor | PD 0325901-Cl (CI-1055-S)  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
PD 0325901-Cl (CI-1055-S)   C16H14O4N2F2ClI 498.65 391210-10-9 160968186 MEK1

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ABL 89 0
AMPK 92 5
ASK1 98 7
Aurora A 99 10
Aurora B 94 1
BRK 106 3
BRSK1 86 7
BRSK2 111 5
BTK 104 9
CAMK1 96 7
CAMKK beta 92 2
CDK2-Cyclin A 92 8
CHK1 91 15
CHK2 85 6
CK1 delta 90 12
CK2 100 12
CLK2 87 6
CSK 86 5
DAPK1 92 4
DYRK1A 94 11
DYRK2 94 4
DYRK3 93 9
EF2K 92 15
EIF2AK3 109 9
EPH-A2 90 10
EPH-A4 100 3
EPH-B1 103 7
EPH-B2 121 2
EPH-B3 108 2
EPH-B4 95 7
ERK1 98 13
ERK2 94 2
ERK8 96 11
FGF-R1 94 9
GCK 97 1
GSK3 beta 93 12
HER4 97 5
HIPK1 109 7
HIPK2 94 4
HIPK3 82 12
IGF-1R 88 9
IKK beta 92 10
IKK epsilon 95 8
IR 104 2
IRAK1 95 5
IRAK4 93 9
IRR 94 8
JAK2
8
 1
JNK1 91 4
JNK2 90 10
JNK3 73 3
Lck 95 3
LKB1 104 3
MAPKAP-K2 87 1
MAPKAP-K3 98 1
MARK1 86 12
MARK2 97 14
MARK3 100 10
MARK4 93 5
MEKK1 88 5
MELK 91 14
MINK1 98 9
MKK1 20 5
MKK2 48 1
MKK6 82 1
MLK1 84 6
MLK3 98 7
MNK1 92 4
MNK2 94 5
MPSK1 84 0
MSK1 84 3
MST2 96 0
MST4 93 2
NEK2a 92 8
NEK6 90 10
NUAK1 91 5
OSR1 98 10
p38 alpha MAPK 97 13
p38 beta MAPK 110 11
p38 delta MAPK 93 5
p38 gamma MAPK 83 9
PAK2 92 2
PAK4 87 11
PAK5 102 5
PAK6 89 4
PDK1 90 13
PHK 95 9
PIM1 90 9
PIM2 100 7
PIM3 98 4
PKA 84 11
PKB alpha 99 8
PKB beta 85 0
PKC alpha 89 12
PKC gamma 94 10
PKC zeta 96 7
PKD1 78 5
PLK1 104 6
PRAK 82 4
PRK2 89 1
RIPK2 87 7
ROCK 2 77 5
RSK1 103 7
RSK2 92 1
S6K1 106 3
SGK1 94 2
SmMLCK 81 8
Src 94 1
SRPK1 85 6
STK33 102 4
SYK 114 8
TAK1 102 11
TAO1 97 14
TBK1 88 0
TIE2 92 1
TLK1 92 10
TrkA 91 9
TTK 96 10
VEGFR1 90 1
YES1 96 4
ZAP70 99 10
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ABL 108 0
AMPK 94 1
ASK1 101 2
Aurora A 106 6
Aurora B 86 1
BRK 112 10
BRSK1 94 2
BRSK2 102 12
BTK 101 2
CAMK1 95 1
CAMKK beta 108 2
CDK2-Cyclin A 90 2
CHK1 115 22
CHK2 98 4
CK1 delta 88 6
CK2 103 20
CLK2 88 0
CSK 89 5
DAPK1 96 1
DYRK1A 95 10
DYRK2 103 13
DYRK3 96 14
EF2K 96 14
EIF2AK3 107 1
EPH-A2 101 6
EPH-A4 98 4
EPH-B1 94 10
EPH-B2 111 3
EPH-B3 93 3
EPH-B4 90 11
ERK1 95 13
ERK2 91 2
ERK8 90 15
FGF-R1 94 7
GCK 104 5
GSK3 beta 97 6
HER4 121 0
HIPK1 99 14
HIPK2 101 13
HIPK3 95 6
IGF-1R 81 8
IKK beta 101 10
IKK epsilon 101 8
IR 97 21
IRAK1 84 1
IRAK4 92 5
IRR 92 11
JAK2
8
 0
JNK1 92 1
JNK2 90 4
JNK3 86 1
Lck 98 10
LKB1 112 3
MAPKAP-K2 101 2
MAPKAP-K3 81 14
MARK1 83 3
MARK2 103 8
MARK3 75 4
MARK4 92 13
MEKK1 101 4
MELK 97 7
MINK1 117 12
MKK1
3
 2
MKK2 14 5
MKK6 61 15
MLK1 74 8
MLK3 100 2
MNK1 92 11
MNK2 101 6
MPSK1 84 13
MSK1 112 5
MST2 96 10
MST4 103 11
NEK2a 105 4
NEK6 91 6
NUAK1 93 5
OSR1 84 1
p38 alpha MAPK 102 5
p38 beta MAPK 129 5
p38 delta MAPK 101 12
p38 gamma MAPK 92 2
PAK2 83 11
PAK4 80 7
PAK5 87 1
PAK6 98 12
PDK1 98 6
PHK 100 5
PIM1 62 3
PIM2 88 7
PIM3 68 5
PKA 110 0
PKB alpha 104 2
PKB beta 92 1
PKC alpha 83 7
PKC gamma 95 12
PKC zeta 93 4
PKD1 90 9
PLK1 104 5
PRAK 94 1
PRK2 84 1
RIPK2 81 8
ROCK 2 102 4
RSK1 115 5
RSK2 95 7
S6K1 110 21
SGK1 108 5
SmMLCK 84 15
Src 80 11
SRPK1 103 0
STK33 102 4
SYK 91 13
TAK1 101 2
TAO1 111 13
TBK1 98 10
TIE2 94 1
TLK1 99 12
TrkA 88 13
TTK 82 1
VEGFR1 98 4
YES1 91 5
ZAP70 90 8