Inhibitor | AG879 (Tyrphostin)
Screening Results Tables
Screen Conc: 0.10µM
| Kinase |
% Activity Remaining |
Standard Deviation |
| AMPK |
78
|
0 |
| BRSK2 |
87
|
9 |
| BTK |
55
|
4 |
| CAMK1 |
85
|
9 |
| CAMKK beta |
78
|
22 |
| CDK2-Cyclin A |
110
|
1 |
| CHK1 |
86
|
1 |
| CHK2 |
109
|
23 |
| CK1 delta |
95
|
0 |
| CK2 |
123
|
8 |
| CSK |
92
|
15 |
| DYRK1A |
84
|
1 |
| DYRK2 |
110
|
8 |
| DYRK3 |
98
|
11 |
| EF2K |
105
|
4 |
| EPH-A2 |
94
|
12 |
| EPH-B3 |
96
|
10 |
| ERK1 |
88
|
16 |
| ERK2 |
91
|
2 |
| ERK8 |
96
|
2 |
| FGF-R1 |
120
|
17 |
| GSK3 beta |
95
|
7 |
| HIPK2 |
118
|
15 |
| IGF-1R |
98
|
16 |
| IKK beta |
109
|
10 |
| IKK epsilon |
78
|
8 |
| IR |
118
|
7 |
| IRR |
88
|
0 |
| JNK1 |
99
|
9 |
| JNK2 |
90
|
10 |
| Lck |
99
|
8 |
| MAPKAP-K2 |
108
|
11 |
| MARK3 |
92
|
6 |
| MELK |
76
|
1 |
| MKK1 |
95
|
1 |
| MNK1 |
101
|
4 |
| MNK2 |
84
|
0 |
| MSK1 |
82
|
3 |
| MST2 |
113
|
8 |
| MST4 |
83
|
0 |
| NEK2a |
85
|
17 |
| NEK6 |
100
|
24 |
| p38 alpha MAPK |
105
|
7 |
| p38 beta MAPK |
89
|
6 |
| p38 delta MAPK |
93
|
11 |
| p38 gamma MAPK |
98
|
7 |
| PAK4 |
105
|
11 |
| PAK5 |
585
|
715 |
| PAK6 |
86
|
1 |
| PDK1 |
100
|
0 |
| PHK |
93
|
19 |
| PIM1 |
102
|
22 |
| PIM2 |
98
|
1 |
| PIM3 |
98
|
19 |
| PKA |
85
|
3 |
| PKB alpha |
103
|
1 |
| PKB beta |
84
|
3 |
| PKC alpha |
101
|
10 |
| PKC zeta |
86
|
7 |
| PKD1 |
99
|
12 |
| PLK1 |
105
|
9 |
| PRAK |
102
|
2 |
| PRK2 |
101
|
30 |
| ROCK 2 |
113
|
10 |
| RSK1 |
99
|
9 |
| RSK2 |
67
|
2 |
| S6K1 |
92
|
4 |
| SGK1 |
124
|
15 |
| SmMLCK |
85
|
20 |
| Src |
95
|
11 |
| SRPK1 |
86
|
0 |
| SYK |
173
|
70 |
| TBK1 |
90
|
6 |
| VEGFR1 |
92
|
3 |
| YES1 |
111
|
13 |
Screen Conc: 10.00µM
| Kinase |
% Activity Remaining |
Standard Deviation |
| AMPK |
70
|
2 |
| BRSK2 |
66
|
4 |
| BTK |
46
|
8 |
| CAMK1 |
88
|
7 |
| CAMKK beta |
44
|
12 |
| CDK2-Cyclin A |
40
|
0 |
| CHK1 |
92
|
19 |
| CHK2 |
96
|
14 |
| CK1 delta |
92
|
6 |
| CK2 |
118
|
5 |
| CSK |
89
|
6 |
| DYRK1A |
56
|
3 |
| DYRK2 |
102
|
31 |
| DYRK3 |
60
|
1 |
| EF2K |
90
|
8 |
| EPH-A2 |
113
|
11 |
| EPH-B3 |
55
|
1 |
| ERK1 |
90
|
8 |
| ERK2 |
87
|
1 |
| ERK8 |
37
|
0 |
| FGF-R1 |
59
|
0 |
| GSK3 beta |
39
|
4 |
| HIPK2 |
21
|
2 |
| IGF-1R |
86
|
4 |
| IKK beta |
105
|
13 |
| IKK epsilon |
63
|
9 |
| IR |
139
|
52 |
| IRR |
45
|
4 |
| JNK1 |
87
|
16 |
| JNK2 |
70
|
9 |
| Lck |
107
|
13 |
| MAPKAP-K2 |
99
|
2 |
| MARK3 |
90
|
7 |
| MELK |
8
|
4 |
| MKK1 |
83
|
13 |
| MNK1 |
99
|
8 |
| MNK2 |
76
|
9 |
| MSK1 |
88
|
3 |
| MST2 |
54
|
1 |
| MST4 |
72
|
14 |
| NEK2a |
82
|
18 |
| NEK6 |
101
|
16 |
| p38 alpha MAPK |
81
|
9 |
| p38 beta MAPK |
86
|
8 |
| p38 delta MAPK |
86
|
11 |
| p38 gamma MAPK |
92
|
3 |
| PAK4 |
56
|
2 |
| PAK5 |
519
|
649 |
| PAK6 |
80
|
1 |
| PDK1 |
96
|
5 |
| PHK |
28
|
1 |
| PIM1 |
25
|
3 |
| PIM2 |
53
|
5 |
| PIM3 |
34
|
8 |
| PKA |
93
|
10 |
| PKB alpha |
94
|
4 |
| PKB beta |
15
|
9 |
| PKC alpha |
78
|
6 |
| PKC zeta |
67
|
2 |
| PKD1 |
80
|
3 |
| PLK1 |
13
|
2 |
| PRAK |
27
|
2 |
| PRK2 |
114
|
16 |
| ROCK 2 |
94
|
0 |
| RSK1 |
79
|
1 |
| RSK2 |
61
|
4 |
| S6K1 |
64
|
14 |
| SGK1 |
107
|
13 |
| SmMLCK |
52
|
5 |
| Src |
67
|
0 |
| SRPK1 |
61
|
12 |
| SYK |
138
|
2 |
| TBK1 |
97
|
1 |
| VEGFR1 |
50
|
3 |
| YES1 |
85
|
1 |
