Inhibitor | LY294002  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
LY294002   C19H17NO3 307.40 154447-36-6 3973 PI3K Baumann P. and West S.C. (1998) Proc. Natl. Acad. Sci. USA 95 14066 Cardone M.H. (1998) Science 282 1318

Screening Results Chart

Screening Results Tables

Screen Conc: 50.00µM
Kinase % Activity Remaining Standard Deviation
CK2
2
 3
PIM3
2
 0
PIM1
3
 1
PLK1
4
 0
HIPK2
7
 0
GSK3 beta
8
 0
DYRK1A 24 2
HIPK3 25 1
CK1 delta 32 0
PIM2 33 5
RSK1 36 1
DYRK3 39 1
Lck 40 3
ERK8 41 2
PHK 42 5
SmMLCK 43 2
BRSK2 44 1
EF2K 44 4
PRK2 45 0
IKK beta 45 1
CAMKK beta 49 5
PKC alpha 49 3
MELK 52 4
PRAK 55 2
RSK2 57 9
PKA 60 1
CDK2-Cyclin A 60 1
CSK 60 1
MST2 61 1
CAMKK alpha 63 1
p38 delta MAPK 66 5
PKB alpha 67 5
SGK1 67 0
Aurora B 68 7
NEK6 69 1
PAK4 70 6
SRPK1 71 1
CAMK1 72 1
MSK1 72 1
Aurora C 72 3
NEK2a 73 4
PKC zeta 73 8
PDK1 74 7
S6K1 76 1
PKB beta 77 7
PAK5 77 8
MNK1 77 2
MKK1 78 0
PKD1 78 0
DYRK2 79 5
CHK1 79 0
PAK6 80 7
JNK3 80 0
NEK7 80 8
Src 81 3
MNK2 81 1
MARK3 82 0
JNK2 83 1
MAPKAP-K2 84 7
ROCK 2 84 6
AMPK 85 2
MAPKAP-K3 88 1
ERK1 88 1
ERK2 89 7
JNK1 91 1
p38 alpha MAPK 94 5
p38 gamma MAPK 95 1
CHK2 103 2
p38 beta MAPK 109 4
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
PIM1
8
 1
PIM3 13 2
CK2 23 5
PLK1 26 0
GSK3 beta 37 3
HIPK2 38 1
IRR 55 8
CK1 delta 56 3
PIM2 65 1
IKK beta 67 4
PAK4 67 4
Aurora B 69 3
ERK8 69 4
CAMKK alpha 71 4
CAMKK beta 71 4
PRK2 74 7
DYRK1A 75 9
PKC alpha 76 6
MNK1 77 5
HIPK3 77 2
DYRK3 78 2
MARK3 79 13
CDK2-Cyclin A 80 1
PKB beta 81 8
CHK1 82 12
EF2K 83 3
PRAK 83 6
CHK2 83 0
Aurora C 84 2
MST2 84 0
MELK 85 8
MKK1 85 0
ERK1 85 7
JNK3 86 2
NEK7 86 0
CAMK1 87 14
PDK1 88 2
ERK2 88 11
SmMLCK 88 7
p38 gamma MAPK 89 3
ROCK 2 89 10
MST4 90 1
YES1 90 3
S6K1 90 2
NEK2a 90 8
RSK1 92 3
PAK5 92 5
JNK1 92 5
EPH-A2 94 4
MNK2 94 4
DYRK2 94 3
PHK 94 9
PKB alpha 95 3
FGF-R1 95 2
AMPK 96 7
Lck 96 2
PKA 97 0
JNK2 97 2
PAK6 99 0
p38 beta MAPK 100 5
SRPK1 100 5
IKK epsilon 100 3
p38 delta MAPK 101 13
p38 alpha MAPK 101 10
TBK1 102 4
MAPKAP-K2 102 3
MSK1 103 0
RSK2 103 4
BRSK2 103 4
CSK 103 2
NEK6 103 4
SGK1 104 4
PKD1 105 2
Src 105 10
PKC zeta 114 5
SYK 115 9
MAPKAP-K3 119 4
Screen Conc: 5.00µM
Kinase % Activity Remaining Standard Deviation
PIM1 11 1
PIM3 19 0
PLK1 21 0
CK2 40 7
HIPK2 43 9
CDK2-Cyclin A 44 1
GSK3 beta 56 3
MARK3 66 0
IKK beta 68 4
DYRK3 69 5
IRR 72 0
PRK2 74 3
CAMKK beta 74 7
PKC alpha 77 4
MST4 78 10
CK1 delta 78 0
ERK1 80 2
CHK2 81 0
PRAK 81 10
Aurora B 83 9
PAK4 84 5
Aurora C 86 13
MKK1 86 4
PKD1 87 7
MNK1 87 6
ERK8 87 5
PKB beta 87 6
NEK2a 90 12
NEK7 90 0
DYRK1A 91 4
S6K1 92 2
MST2 92 7
PDK1 92 2
ERK2 93 3
HIPK3 93 4
FGF-R1 94 10
PIM2 94 3
p38 gamma MAPK 95 4
YES1 95 2
DYRK2 95 7
IKK epsilon 96 2
CAMK1 96 5
CHK1 97 5
NEK6 97 7
p38 beta MAPK 97 10
Src 98 5
PHK 99 3
JNK3 100 6
MSK1 101 8
PKA 102 6
ROCK 2 102 8
PKC zeta 102 0
RSK1 102 2
Lck 103 6
MELK 103 4
PAK6 104 6
JNK2 105 1
AMPK 105 0
PAK5 107 15
MNK2 108 3
SYK 110 5
BRSK2 110 9
SGK1 110 9
SRPK1 111 3
PKB alpha 111 10
p38 alpha MAPK 112 13
p38 delta MAPK 112 6
EF2K 114 1
TBK1 116 5
MAPKAP-K2 117 0
CSK 118 10
JNK1 119 1
SmMLCK 119 8
MAPKAP-K3 120 1
RSK2 128 3
EPH-A2 142 1