Inhibitor | IKK-3 inhibitor IX  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
IKK-3 inhibitor IX   C22H19N3O5S2 469.50 862812-98-4 11626927 IKK3 Bamborough P. (2006) Bioorg. Med. Chem. Lett. 16 6236

Screening Results Chart

Screening Results Tables

Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
MINK1
1
 0
MLK3
3
 2
Aurora B
4
 1
PHK
4
 0
IRAK4
6
 2
RIPK2
6
 0
Aurora A
6
 0
IKK epsilon
6
 1
MST2
7
 1
GCK
8
 0
MLK1
8
 1
AMPK
9
 3
ERK8 15 4
TBK1 17 3
CLK2 18 0
JAK2 18 1
CHK2 19 3
VEGFR1 23 2
EPH-B3 27 4
TAO1 27 1
RSK1 28 6
TrkA 28 4
BRSK2 30 4
MARK1 31 2
HIPK2 32 7
Lck 33 2
MNK1 34 0
BRSK1 34 5
NUAK1 35 2
MNK2 35 1
MARK2 35 4
NEK2a 39 3
MARK3 41 2
PAK4 41 3
MARK4 42 1
EPH-A4 45 3
BTK 45 13
MST4 47 5
FGF-R1 49 5
EPH-B2 50 5
DAPK1 51 1
PDK1 52 10
EPH-A2 53 9
MEKK1 54 12
PLK1 55 2
RSK2 57 9
MKK2 57 9
PAK5 58 6
MSK1 58 3
HIPK1 58 1
YES1 58 0
MELK 59 7
HIPK3 61 1
SmMLCK 61 1
ROCK 2 61 8
LKB1 62 5
Src 64 1
CHK1 64 6
PRK2 64 8
IRR 66 4
S6K1 66 7
PAK6 67 0
MAPKAP-K3 67 1
GSK3 beta 68 2
ASK1 69 1
TAK1 70 6
PIM1 71 6
DYRK2 72 3
PIM3 73 0
CSK 74 3
MKK1 75 10
TTK 77 5
NEK6 77 1
ERK1 77 10
JNK3 77 6
IKK beta 78 11
PIM2 78 10
SRPK1 79 9
CAMK1 80 1
DYRK1A 81 3
DYRK3 82 12
EPH-B4 82 12
p38 beta MAPK 83 0
PKA 83 6
MKK6 84 4
HER4 84 11
p38 alpha MAPK 85 3
MAPKAP-K2 85 4
PKB alpha 85 10
p38 delta MAPK 86 14
CAMKK beta 86 4
PRAK 87 1
JNK1 87 1
SYK 87 9
SGK1 88 2
ERK2 88 4
PKC alpha 88 1
JNK2 90 4
CK1 delta 91 0
PKD1 92 3
IGF-1R 92 3
p38 gamma MAPK 94 3
PKC zeta 95 4
EPH-B1 95 2
EF2K 98 5
PKB beta 98 2
CDK2-Cyclin A 99 1
IR 105 8
CK2 107 11
PAK2 111 3
Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
MINK1
5
 1
PHK
5
 0
MLK3
5
 1
Aurora B
6
 1
IKK epsilon
9
 2
AMPK
10
 1
IRAK4 13 1
RIPK2 14 3
VEGFR1 15 2
MST2 19 1
CHK2 19 3
TBK1 21 3
GCK 24 2
MLK1 28 1
Aurora A 29 0
TrkA 30 1
MARK3 31 1
BRSK2 31 0
MARK1 33 5
JAK2 34 7
Lck 35 10
NUAK1 35 5
MARK2 39 1
BRSK1 40 1
EPH-B3 40 3
NEK2a 41 1
YES1 43 2
CLK2 47 0
MNK1 47 0
MNK2 47 8
HIPK2 49 3
FGF-R1 49 2
RSK1 50 5
PAK4 53 6
DAPK1 54 6
Src 57 4
MARK4 57 9
EPH-A4 57 5
TAO1 61 3
EPH-B2 62 6
BTK 63 6
PRK2 63 0
PLK1 65 2
ERK8 65 7
EPH-A2 66 4
PDK1 71 11
PKB beta 72 2
DYRK1A 73 6
DYRK3 75 3
MKK2 75 0
MST4 76 4
IRR 77 11
MEKK1 77 5
HER4 78 2
MSK1 78 4
MKK1 78 8
EPH-B1 79 8
CHK1 79 8
LKB1 80 3
PAK5 80 1
CSK 81 7
RSK2 82 2
TTK 83 1
ASK1 83 2
DYRK2 84 8
MELK 84 8
S6K1 87 0
CK1 delta 89 7
IGF-1R 89 6
SmMLCK 89 2
GSK3 beta 90 7
CAMK1 90 12
PIM3 90 5
p38 alpha MAPK 91 1
MKK6 91 6
JNK1 92 1
PKD1 93 5
p38 gamma MAPK 93 9
NEK6 93 4
MAPKAP-K3 93 2
PIM2 93 3
SRPK1 93 2
ROCK 2 93 11
EPH-B4 94 4
PAK2 94 6
PIM1 94 1
PAK6 95 1
SYK 95 12
JNK2 95 7
PKC alpha 96 4
PKC zeta 97 0
PKB alpha 98 0
JNK3 99 5
MAPKAP-K2 99 5
HIPK1 99 1
TAK1 100 8
CDK2-Cyclin A 100 10
PRAK 101 7
ERK1 101 12
PKA 101 0
HIPK3 102 5
p38 beta MAPK 103 3
IKK beta 103 8
IR 104 4
ERK2 104 12
SGK1 105 4
EF2K 105 1
p38 delta MAPK 112 14
CAMKK beta 112 1
CK2 118 5