Inhibitor | IKK-3 inhibitor IX  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
IKK-3 inhibitor IX   C22H19N3O5S2 469.50 862812-98-4 11626927 IKK3 Bamborough P. (2006) Bioorg. Med. Chem. Lett. 16 6236

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
AMPK
10
 1
ASK1 83 2
Aurora A 29 0
Aurora B
6
 1
BRSK1 40 1
BRSK2 31 0
BTK 63 6
CAMK1 90 12
CAMKK beta 112 1
CDK2-Cyclin A 100 10
CHK1 79 8
CHK2 19 3
CK1 delta 89 7
CK2 118 5
CLK2 47 0
CSK 81 7
DAPK1 54 6
DYRK1A 73 6
DYRK2 84 8
DYRK3 75 3
EF2K 105 1
EPH-A2 66 4
EPH-A4 57 5
EPH-B1 79 8
EPH-B2 62 6
EPH-B3 40 3
EPH-B4 94 4
ERK1 101 12
ERK2 104 12
ERK8 65 7
FGF-R1 49 2
GCK 24 2
GSK3 beta 90 7
HER4 78 2
HIPK1 99 1
HIPK2 49 3
HIPK3 102 5
IGF-1R 89 6
IKK beta 103 8
IKK epsilon
9
 2
IR 104 4
IRAK4 13 1
IRR 77 11
JAK2 34 7
JNK1 92 1
JNK2 95 7
JNK3 99 5
Lck 35 10
LKB1 80 3
MAPKAP-K2 99 5
MAPKAP-K3 93 2
MARK1 33 5
MARK2 39 1
MARK3 31 1
MARK4 57 9
MEKK1 77 5
MELK 84 8
MINK1
5
 1
MKK1 78 8
MKK2 75 0
MKK6 91 6
MLK1 28 1
MLK3
5
 1
MNK1 47 0
MNK2 47 8
MSK1 78 4
MST2 19 1
MST4 76 4
NEK2a 41 1
NEK6 93 4
NUAK1 35 5
p38 alpha MAPK 91 1
p38 beta MAPK 103 3
p38 delta MAPK 112 14
p38 gamma MAPK 93 9
PAK2 94 6
PAK4 53 6
PAK5 80 1
PAK6 95 1
PDK1 71 11
PHK
5
 0
PIM1 94 1
PIM2 93 3
PIM3 90 5
PKA 101 0
PKB alpha 98 0
PKB beta 72 2
PKC alpha 96 4
PKC zeta 97 0
PKD1 93 5
PLK1 65 2
PRAK 101 7
PRK2 63 0
RIPK2 14 3
ROCK 2 93 11
RSK1 50 5
RSK2 82 2
S6K1 87 0
SGK1 105 4
SmMLCK 89 2
Src 57 4
SRPK1 93 2
SYK 95 12
TAK1 100 8
TAO1 61 3
TBK1 21 3
TrkA 30 1
TTK 83 1
VEGFR1 15 2
YES1 43 2
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
AMPK
9
 3
ASK1 69 1
Aurora A
6
 0
Aurora B
4
 1
BRSK1 34 5
BRSK2 30 4
BTK 45 13
CAMK1 80 1
CAMKK beta 86 4
CDK2-Cyclin A 99 1
CHK1 64 6
CHK2 19 3
CK1 delta 91 0
CK2 107 11
CLK2 18 0
CSK 74 3
DAPK1 51 1
DYRK1A 81 3
DYRK2 72 3
DYRK3 82 12
EF2K 98 5
EPH-A2 53 9
EPH-A4 45 3
EPH-B1 95 2
EPH-B2 50 5
EPH-B3 27 4
EPH-B4 82 12
ERK1 77 10
ERK2 88 4
ERK8 15 4
FGF-R1 49 5
GCK
8
 0
GSK3 beta 68 2
HER4 84 11
HIPK1 58 1
HIPK2 32 7
HIPK3 61 1
IGF-1R 92 3
IKK beta 78 11
IKK epsilon
6
 1
IR 105 8
IRAK4
6
 2
IRR 66 4
JAK2 18 1
JNK1 87 1
JNK2 90 4
JNK3 77 6
Lck 33 2
LKB1 62 5
MAPKAP-K2 85 4
MAPKAP-K3 67 1
MARK1 31 2
MARK2 35 4
MARK3 41 2
MARK4 42 1
MEKK1 54 12
MELK 59 7
MINK1
1
 0
MKK1 75 10
MKK2 57 9
MKK6 84 4
MLK1
8
 1
MLK3
3
 2
MNK1 34 0
MNK2 35 1
MSK1 58 3
MST2
7
 1
MST4 47 5
NEK2a 39 3
NEK6 77 1
NUAK1 35 2
p38 alpha MAPK 85 3
p38 beta MAPK 83 0
p38 delta MAPK 86 14
p38 gamma MAPK 94 3
PAK2 111 3
PAK4 41 3
PAK5 58 6
PAK6 67 0
PDK1 52 10
PHK
4
 0
PIM1 71 6
PIM2 78 10
PIM3 73 0
PKA 83 6
PKB alpha 85 10
PKB beta 98 2
PKC alpha 88 1
PKC zeta 95 4
PKD1 92 3
PLK1 55 2
PRAK 87 1
PRK2 64 8
RIPK2
6
 0
ROCK 2 61 8
RSK1 28 6
RSK2 57 9
S6K1 66 7
SGK1 88 2
SmMLCK 61 1
Src 64 1
SRPK1 79 9
SYK 87 9
TAK1 70 6
TAO1 27 1
TBK1 17 3
TrkA 28 4
TTK 77 5
VEGFR1 23 2
YES1 58 0