Inhibitor | H-89, Dihydrochloride  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	94	4
AMPK	24	0
AMPK (hum)	70	2
ASK1	95	1
Aurora A	88	3
Aurora B	63	8
BRK	88	6
BRSK1	85	8
BRSK2	82	4
BTK	98	8
CAMK1	104	1
CAMKK beta	94	4
CDK2-Cyclin A	75	4
CDK9-Cyclin T1	89	0
CHK1	67	0
CHK2	82	0
CK1 delta	86	8
CK1 gamma 2	96	0
CK2	98	3
CLK2	95	1
CSK	88	4
DAPK1	94	5
DDR2	95	11
DYRK1A	95	7
DYRK2	105	9
DYRK3	72	0
EF2K	120	1
EIF2AK3	69	17
EPH-A2	97	5
EPH-A4	97	7
EPH-B1	97	6
EPH-B2	100	5
EPH-B3	100	1
EPH-B4	89	0
ERK1	86	2
ERK2	91	4
ERK5	107	14
ERK8	102	9
FGF-R1	90	10
GCK	93	9
GSK3 beta	88	3
HER4	102	2
HIPK1	101	8
HIPK2	111	2
HIPK3	108	7
IGF-1R	88	2
IKK beta	98	2
IKK epsilon	105	6
IR	102	19
IRAK1	100	3
IRAK4	104	7
IRR	88	6
JAK2	104	0
JNK1	90	1
JNK2	93	5
JNK3	97	0
Lck	72	3
LKB1	76	1
MAP4K3	93	8
MAP4K5	105	14
MAPKAP-K2	98	9
MAPKAP-K3	104	0
MARK1	95	8
MARK2	90	4
MARK3	67	3
MARK4	98	8
MEKK1	90	9
MELK	42	0
MINK1	82	5
MKK1	73	7
MKK2	83	6
MKK6	86	2
MLK1	91	0
MLK3	88	0
MNK1	93	1
MNK2	97	1
MPSK1	99	6
MSK1	7	2
MST2	72	6
MST3	92	2
MST4	88	4
NEK2a	102	7
NEK6	104	6
NUAK1	18	1
OSR1	109	20
p38 alpha MAPK	93	0
p38 beta MAPK	100	1
p38 delta MAPK	98	3
p38 gamma MAPK	101	1
PAK2	97	5
PAK4	90	1
PAK5	91	2
PAK6	93	0
PDGFRA	98	6
PDK1	81	6
PHK	66	3
PIM1	89	2
PIM2	77	7
PIM3	59	0
PKA	6	0
PKB alpha	14	0
PKB beta	13	3
PKC alpha	63	3
PKC gamma	71	4
PKC zeta	105	7
PKD1	64	7
PLK1	92	0
PRAK	95	5
PRK2	6	2
RIPK2	92	11
ROCK 2	5	0
RSK1	24	0
RSK2	40	7
S6K1	10	0
SGK1	61	0
SIK2	84	0
SIK3	109	7
SmMLCK	86	6
Src	96	7
SRPK1	89	4
STK33	42	3
SYK	96	3
TAK1	87	2
TAO1	87	2
TBK1	91	29
TESK1	98	19
TGFBR1	106	3
TIE2	117	1
TLK1	94	12
TrkA	107	1
TSSK1	63	10
TTBK1	105	14
TTBK2	95	6
TTK	75	0
ULK1	98	4
ULK2	97	1
VEGFR1	89	4
WNK1	79	2
YES1	99	2
ZAP70	107	3

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	101	4
AMPK	26	1
AMPK (hum)	14	6
ASK1	99	4
Aurora A	56	3
Aurora B	45	1
BRK	86	7
BRSK1	39	7
BRSK2	30	1
BTK	79	8
CAMK1	47	0
CAMKK beta	85	6
CDK2-Cyclin A	41	4
CDK9-Cyclin T1	65	1
CHK1	24	4
CHK2	14	1
CK1 delta	72	2
CK1 gamma 2	107	14
CK2	102	9
CLK2	55	1
CSK	99	4
DAPK1	44	2
DDR2	85	20
DYRK1A	93	1
DYRK2	93	5
DYRK3	15	2
EF2K	106	0
EIF2AK3	90	23
EPH-A2	76	4
EPH-A4	81	9
EPH-B1	100	11
EPH-B2	94	9
EPH-B3	72	5
EPH-B4	101	5
ERK1	81	4
ERK2	93	5
ERK5	81	16
ERK8	13	0
FGF-R1	27	9
GCK	24	1
GSK3 beta	91	5
HER4	84	12
HIPK1	97	13
HIPK2	96	11
HIPK3	102	3
IGF-1R	57	3
IKK beta	94	3
IKK epsilon	96	12
IR	114	13
IRAK1	39	4
IRAK4	83	5
IRR	73	2
JAK2	86	6
JNK1	93	3
JNK2	99	4
JNK3	93	0
Lck	77	7
LKB1	78	8
MAP4K3	49	8
MAP4K5	94	0
MAPKAP-K2	55	1
MAPKAP-K3	91	1
MARK1	62	8
MARK2	35	4
MARK3	29	4
MARK4	63	9
MEKK1	94	4
MELK	38	4
MINK1	34	1
MKK1	54	3
MKK2	46	3
MKK6	97	0
MLK1	51	3
MLK3	70	1
MNK1	87	1
MNK2	87	3
MPSK1	100	2
MSK1	5	0
MST2	57	0
MST3	49	1
MST4	53	10
NEK2a	94	8
NEK6	102	9
NUAK1	4	1
OSR1	97	2
p38 alpha MAPK	100	5
p38 beta MAPK	101	4
p38 delta MAPK	75	4
p38 gamma MAPK	96	4
PAK2	94	8
PAK4	65	1
PAK5	84	0
PAK6	68	7
PDGFRA	67	11
PDK1	95	3
PHK	54	5
PIM1	87	2
PIM2	105	4
PIM3	81	3
PKA	1	0
PKB alpha	5	2
PKB beta	12	1
PKC alpha	77	2
PKC gamma	38	2
PKC zeta	35	2
PKD1	31	2
PLK1	93	2
PRAK	65	4
PRK2	6	4
RIPK2	99	1
ROCK 2	6	1
RSK1	8	1
RSK2	19	2
S6K1	3	0
SGK1	16	0
SIK2	50	2
SIK3	71	0
SmMLCK	70	6
Src	94	6
SRPK1	91	1
STK33	11	0
SYK	94	11
TAK1	67	2
TAO1	65	4
TBK1	88	6
TESK1	93	7
TGFBR1	113	6
TIE2	91	10
TLK1	88	15
TrkA	83	12
TSSK1	66	20
TTBK1	110	25
TTBK2	100	4
TTK	106	2
ULK1	71	5
ULK2	71	9
VEGFR1	13	1
WNK1	85	17
YES1	85	5
ZAP70	124	9