Inhibitor |
H-8, Dihydrochloride
Screening Results Tables
Screen Conc:
10.00µM
| Kinase |
% Activity Remaining |
Standard Deviation |
|
AMPK
|
19
|
0
|
|
Aurora B
|
79
|
7
|
|
Aurora C
|
72
|
2
|
|
BRSK2
|
42
|
8
|
|
CAMK1
|
98
|
7
|
|
CAMKK alpha
|
80
|
8
|
|
CAMKK beta
|
76
|
6
|
|
CDK2-Cyclin A
|
52
|
6
|
|
CHK1
|
77
|
5
|
|
CHK2
|
114
|
1
|
|
CK1 delta
|
86
|
4
|
|
CK2
|
83
|
5
|
|
CSK
|
75
|
1
|
|
DYRK1A
|
90
|
3
|
|
DYRK2
|
95
|
4
|
|
DYRK3
|
34
|
3
|
|
EF2K
|
119
|
11
|
|
ERK1
|
87
|
1
|
|
ERK2
|
95
|
4
|
|
ERK8
|
87
|
5
|
|
GSK3 beta
|
42
|
1
|
|
HIPK2
|
101
|
4
|
|
HIPK3
|
98
|
2
|
|
IKK beta
|
88
|
5
|
|
JNK1
|
92
|
3
|
|
JNK2
|
88
|
5
|
|
JNK3
|
107
|
0
|
|
Lck
|
72
|
1
|
|
MAPKAP-K2
|
115
|
1
|
|
MAPKAP-K3
|
92
|
8
|
|
MARK3
|
71
|
7
|
|
MELK
|
23
|
0
|
|
MKK1
|
67
|
9
|
|
MNK1
|
63
|
0
|
|
MNK2
|
79
|
0
|
|
MSK1
|
32
|
0
|
|
MST2
|
51
|
7
|
|
NEK2a
|
94
|
7
|
|
NEK6
|
85
|
4
|
|
NEK7
|
104
|
1
|
|
p38 alpha MAPK
|
114
|
6
|
|
p38 beta MAPK
|
108
|
2
|
|
p38 delta MAPK
|
82
|
1
|
|
p38 gamma MAPK
|
103
|
0
|
|
PAK4
|
92
|
1
|
|
PAK5
|
80
|
8
|
|
PAK6
|
91
|
2
|
|
PDK1
|
84
|
6
|
|
PHK
|
54
|
2
|
|
PIM1
|
79
|
3
|
|
PIM2
|
111
|
8
|
|
PIM3
|
65
|
4
|
|
PKA
|
22
|
1
|
|
PKB alpha
|
40
|
2
|
|
PKB beta
|
59
|
1
|
|
PKC alpha
|
54
|
3
|
|
PKC zeta
|
61
|
1
|
|
PKD1
|
39
|
1
|
|
PLK1
|
77
|
0
|
|
PRAK
|
63
|
4
|
|
PRK2
|
7
|
1
|
|
ROCK 2
|
13
|
0
|
|
RSK1
|
18
|
2
|
|
RSK2
|
39
|
6
|
|
S6K1
|
46
|
4
|
|
SGK1
|
70
|
7
|
|
SmMLCK
|
79
|
9
|
|
Src
|
94
|
1
|
|
SRPK1
|
94
|
6
|
