Inhibitor |
H-1152 (Rho Kinase Inhibitor)
Screening Results Tables
Screen Conc:
1.00µM
| Kinase |
% Activity Remaining |
Standard Deviation |
|
AMPK
|
26
|
0
|
|
Aurora B
|
17
|
6
|
|
Aurora C
|
19
|
5
|
|
BRSK2
|
38
|
7
|
|
BTK
|
68
|
11
|
|
CAMK1
|
110
|
5
|
|
CAMKK alpha
|
108
|
1
|
|
CAMKK beta
|
78
|
2
|
|
CDK2-Cyclin A
|
68
|
5
|
|
CHK1
|
85
|
0
|
|
CHK2
|
81
|
0
|
|
CK1 delta
|
107
|
1
|
|
CK2
|
91
|
4
|
|
CSK
|
79
|
5
|
|
DYRK1A
|
92
|
0
|
|
DYRK2
|
94
|
6
|
|
DYRK3
|
108
|
9
|
|
EF2K
|
97
|
0
|
|
EPH-A2
|
48
|
5
|
|
EPH-B3
|
79
|
3
|
|
ERK1
|
89
|
4
|
|
ERK2
|
97
|
3
|
|
ERK8
|
104
|
0
|
|
FGF-R1
|
34
|
2
|
|
GCK
|
55
|
0
|
|
GSK3 beta
|
92
|
3
|
|
HER4
|
106
|
1
|
|
HIPK2
|
111
|
8
|
|
HIPK3
|
114
|
1
|
|
IGF-1R
|
82
|
8
|
|
IKK beta
|
91
|
6
|
|
IKK epsilon
|
113
|
2
|
|
IR
|
97
|
7
|
|
IRAK4
|
101
|
6
|
|
IRR
|
87
|
2
|
|
JNK1
|
97
|
1
|
|
JNK2
|
96
|
6
|
|
JNK3
|
101
|
0
|
|
Lck
|
55
|
0
|
|
LKB1
|
50
|
3
|
|
MAPKAP-K2
|
93
|
2
|
|
MAPKAP-K3
|
107
|
1
|
|
MARK3
|
49
|
5
|
|
MELK
|
49
|
2
|
|
MINK1
|
103
|
4
|
|
MKK1
|
77
|
5
|
|
MLK1
|
81
|
18
|
|
MLK3
|
85
|
8
|
|
MNK1
|
49
|
2
|
|
MNK2
|
68
|
3
|
|
MSK1
|
38
|
5
|
|
MST2
|
59
|
7
|
|
MST4
|
90
|
6
|
|
NEK2a
|
92
|
1
|
|
NEK6
|
112
|
8
|
|
NEK7
|
102
|
4
|
|
NUAK1
|
50
|
9
|
|
p38 alpha MAPK
|
99
|
2
|
|
p38 beta MAPK
|
103
|
2
|
|
p38 delta MAPK
|
96
|
8
|
|
p38 gamma MAPK
|
98
|
3
|
|
PAK4
|
85
|
1
|
|
PAK5
|
84
|
1
|
|
PAK6
|
89
|
2
|
|
PDK1
|
56
|
5
|
|
PHK
|
21
|
5
|
|
PIM1
|
93
|
0
|
|
PIM2
|
80
|
3
|
|
PIM3
|
54
|
1
|
|
PKA
|
31
|
0
|
|
PKB alpha
|
92
|
2
|
|
PKB beta
|
85
|
3
|
|
PKC alpha
|
60
|
5
|
|
PKC zeta
|
75
|
0
|
|
PKD1
|
86
|
4
|
|
PLK1
|
87
|
6
|
|
PRAK
|
95
|
1
|
|
PRK2
|
15
|
4
|
|
ROCK 2
|
2
|
0
|
|
RSK1
|
21
|
5
|
|
RSK2
|
39
|
7
|
|
S6K1
|
86
|
7
|
|
SGK1
|
81
|
5
|
|
SmMLCK
|
86
|
3
|
|
Src
|
78
|
2
|
|
SRPK1
|
91
|
5
|
|
SYK
|
104
|
2
|
|
TBK1
|
81
|
20
|
|
TTK
|
93
|
9
|
|
VEGFR1
|
108
|
6
|
|
YES1
|
76
|
8
|
