Inhibitor | Gö 7874  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
Gö 7874   C27H26N4O4 • HCl 507.00 287935-76-6 5327863 PKC Kleinschroth J. (1995) Bioorg. Med. Chem. Lett. 5 55

Screening Results Chart

Screening Results Tables

Screen Conc: 0.10µM
Kinase % Activity Remaining Standard Deviation
AMPK 64 8
Aurora B 17 0
Aurora C 48 9
BRSK2 72 5
CAMK1 79 0
CAMKK alpha 109 13
CAMKK beta 113 5
CDK2-Cyclin A 95 2
CHK1 56 5
CHK2 57 3
CK1 delta 103 1
CK2 105 4
CSK 84 4
DYRK1A 96 4
DYRK2 98 9
DYRK3 92 2
EF2K 106 0
ERK1 94 7
ERK2 114 5
ERK8 78 5
GSK3 beta 67 2
HIPK2 97 7
HIPK3 108 11
IKK beta 104 3
JNK1 103 13
JNK2 92 4
JNK3 90 9
Lck 103 1
MAPKAP-K2 107 0
MAPKAP-K3 131 2
MARK3 93 4
MELK 72 7
MKK1 82 2
MNK1 94 4
MNK2 90 0
MSK1 11 2
MST2 20 0
NEK2a 95 4
NEK6 99 0
NEK7 94 9
p38 alpha MAPK 107 12
p38 beta MAPK 119 9
p38 delta MAPK 89 4
p38 gamma MAPK 99 2
PAK4 99 2
PAK5 108 5
PAK6 107 5
PDK1 48 3
PHK 77 14
PIM1
9
 1
PIM2 38 1
PIM3
2
 0
PKA 42 4
PKB alpha 70 0
PKB beta 80 2
PKC alpha
5
 0
PKC zeta 118 0
PKD1 87 9
PLK1 99 4
PRAK 104 8
PRK2 63 0
ROCK 2 118 0
RSK1
10
 8
RSK2
3
 1
S6K1 11 0
SGK1 69 3
SmMLCK 15 1
Src 104 2
SRPK1 113 3
Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 19 1
Aurora B 14 2
Aurora C 13 0
BRSK2 18 5
CAMK1 55 6
CAMKK alpha 97 3
CAMKK beta 68 3
CDK2-Cyclin A 90 4
CHK1 13 0
CHK2 27 2
CK1 delta 83 7
CK2 83 8
CSK 78 0
DYRK1A 68 0
DYRK2 65 6
DYRK3 57 3
EF2K 106 3
ERK1 102 3
ERK2 110 5
ERK8 53 2
GSK3 beta 20 1
HIPK2 55 0
HIPK3 106 0
IKK beta 94 2
JNK1 99 8
JNK2 63 3
JNK3 97 2
Lck 75 3
MAPKAP-K2 93 2
MAPKAP-K3 92 1
MARK3 68 3
MELK 20 4
MKK1 27 0
MNK1 80 1
MNK2 88 2
MSK1
3
 0
MST2
3
 0
NEK2a 80 5
NEK6 87 1
NEK7 84 3
p38 alpha MAPK 106 5
p38 beta MAPK 102 2
p38 delta MAPK 65 7
p38 gamma MAPK 90 4
PAK4 82 0
PAK5 81 3
PAK6 82 2
PDK1 11 1
PHK 17 2
PIM1
1
 0
PIM2
6
 0
PIM3
1
 1
PKA
7
 1
PKB alpha 34 1
PKB beta 44 1
PKC alpha
1
 0
PKC zeta 74 2
PKD1 84 1
PLK1 98 4
PRAK 103 0
PRK2 13 0
ROCK 2 115 6
RSK1
5
 2
RSK2
0
 0
S6K1
2
 0
SGK1 25 1
SmMLCK
6
 2
Src 95 4
SRPK1 89 3
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 24 8
Aurora B 12 2
Aurora C
7
 4
BRSK2
6
 0
CAMK1 16 3
CAMKK alpha 101 4
CAMKK beta 37 4
CDK2-Cyclin A 81 1
CHK1
4
 0
CHK2
10
 1
CK1 delta 68 5
CK2 71 5
CSK 58 4
DYRK1A 41 3
DYRK2 70 3
DYRK3 24 2
EF2K 108 12
ERK1 96 5
ERK2 106 2
ERK8 54 1
GSK3 beta
5
 1
HIPK2 24 0
HIPK3 59 6
IKK beta 80 5
JNK1 60 2
JNK2 35 4
JNK3 87 1
Lck 41 2
MAPKAP-K2 62 0
MAPKAP-K3 79 4
MARK3 33 5
MELK
8
 0
MKK1 16 5
MNK1 62 11
MNK2 70 5
MSK1
3
 0
MST2
2
 0
NEK2a 59 3
NEK6 84 0
NEK7 82 2
p38 alpha MAPK 86 8
p38 beta MAPK 95 4
p38 delta MAPK 37 2
p38 gamma MAPK 74 3
PAK4 66 0
PAK5 85 2
PAK6 71 0
PDK1
3
 0
PHK 11 1
PIM1
2
 3
PIM2
1
 0
PIM3
1
 0
PKA
2
 0
PKB alpha
8
 1
PKB beta 13 0
PKC alpha
1
 0
PKC zeta 62 5
PKD1 47 0
PLK1 79 0
PRAK 108 5
PRK2
4
 0
ROCK 2 112 6
RSK1
5
 4
RSK2
0
 0
S6K1
1
 0
SGK1
6
 0
SmMLCK
3
 1
Src 63 3
SRPK1 77 13