Inhibitor | A-443654  

Screen Conc: 0.01µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	84	8
Aurora B	81	3
Aurora C	100	4
BRSK2	88	9
CAMK1	89	3
CAMKK alpha	112	2
CAMKK beta	83	8
CDK2-Cyclin A	82	5
CHK1	100	3
CHK2	94	8
CK1 delta	95	3
CK2	96	0
CSK	99	2
DYRK1A	10	2
DYRK2	79	5
DYRK3	41	3
EF2K	93	7
ERK1	77	8
ERK2	78	6
ERK8	61	2
GSK3 beta	81	1
HIPK2	73	2
HIPK3	90	0
IKK beta	93	8
JNK1	89	7
JNK2	94	1
JNK3	81	9
Lck	97	8
MAPKAP-K2	92	8
MAPKAP-K3	91	9
MARK3	100	3
MELK	96	2
MKK1	84	2
MNK1	120	3
MNK2	97	2
MSK1	19	2
MST2	76	4
NEK2a	101	5
NEK6	95	2
NEK7	86	8
p38 alpha MAPK	131	2
p38 beta MAPK	114	3
p38 delta MAPK	86	1
p38 gamma MAPK	87	5
PAK4	99	3
PAK5	104	2
PAK6	87	2
PDK1	88	1
PHK	86	7
PIM1	57	8
PIM2	59	0
PIM3	54	6
PKA	26	1
PKB alpha	5	2
PKB beta	17	2
PKC alpha	73	3
PKC zeta	82	3
PKD1	63	3
PLK1	89	5
PRAK	107	3
PRK2	17	2
ROCK 2	48	3
RSK1	78	1
RSK2	74	3
S6K1	88	3
SGK1	78	2
SmMLCK	69	2
Src	91	0
SRPK1	92	8

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	67	3
Aurora B	80	2
Aurora C	92	8
BRSK2	79	1
CAMK1	77	6
CAMKK alpha	117	1
CAMKK beta	63	9
CDK2-Cyclin A	31	2
CHK1	99	2
CHK2	95	2
CK1 delta	74	3
CK2	90	8
CSK	93	7
DYRK1A	7	3
DYRK2	26	1
DYRK3	8	1
EF2K	94	8
ERK1	59	3
ERK2	64	2
ERK8	28	3
GSK3 beta	33	4
HIPK2	24	3
HIPK3	71	2
IKK beta	89	2
JNK1	90	3
JNK2	78	9
JNK3	86	8
Lck	97	3
MAPKAP-K2	73	0
MAPKAP-K3	96	2
MARK3	83	1
MELK	63	2
MKK1	67	6
MNK1	109	2
MNK2	80	5
MSK1	9	2
MST2	29	0
NEK2a	95	2
NEK6	95	4
NEK7	84	1
p38 alpha MAPK	92	6
p38 beta MAPK	105	4
p38 delta MAPK	68	9
p38 gamma MAPK	83	4
PAK4	90	6
PAK5	96	1
PAK6	87	3
PDK1	79	8
PHK	54	6
PIM1	15	2
PIM2	15	2
PIM3	13	1
PKA	3	1
PKB alpha	3	2
PKB beta	2	0
PKC alpha	29	4
PKC zeta	66	0
PKD1	23	4
PLK1	80	1
PRAK	107	4
PRK2	2	2
ROCK 2	8	1
RSK1	32	1
RSK2	27	3
S6K1	32	9
SGK1	53	5
SmMLCK	27	2
Src	86	5
SRPK1	91	2