Inhibitor | Imatinib  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	93	5
ASK1	89	7
Aurora A	111	10
Aurora B	88	8
BRSK1	98	12
BRSK2	80	3
BTK	88	5
CAMK1	91	13
CAMKK beta	83	1
CDK2-Cyclin A	83	0
CHK1	86	3
CHK2	99	7
CK1 delta	87	8
CK2	76	8
CLK2	78	4
CSK	79	3
DAPK1	90	2
DYRK1A	103	1
DYRK2	87	9
DYRK3	84	0
EF2K	67	5
EPH-A2	69	7
EPH-A4	101	14
EPH-B1	94	1
EPH-B2	91	8
EPH-B3	54	3
EPH-B4	97	6
ERK1	82	6
ERK2	73	9
ERK8	77	8
FGF-R1	89	6
GCK	91	2
GSK3 beta	72	7
HER4	67	3
HIPK1	80	1
HIPK2	89	15
HIPK3	86	7
IGF-1R	80	1
IKK beta	74	6
IKK epsilon	54	14
IR	48	8
IRAK4	95	10
IRR	84	7
JAK2	75	0
JNK1	100	6
JNK2	87	7
JNK3	96	7
Lck	29	1
LKB1	84	7
MAPKAP-K2	98	9
MAPKAP-K3	81	2
MARK1	93	7
MARK2	89	3
MARK3	88	1
MARK4	98	14
MEKK1	110	1
MELK	76	4
MINK1	56	9
MKK1	68	3
MKK2	101	11
MKK6	85	2
MLK1	77	1
MLK3	101	5
MNK1	99	2
MNK2	107	8
MSK1	84	5
MST2	82	0
MST4	87	2
NEK2a	98	11
NEK6	88	0
NUAK1	78	4
p38 alpha MAPK	98	14
p38 beta MAPK	75	2
p38 delta MAPK	85	5
p38 gamma MAPK	93	9
PAK2	94	5
PAK4	85	4
PAK5	95	7
PAK6	94	0
PDK1	90	2
PHK	85	3
PIM1	96	1
PIM2	101	9
PIM3	83	3
PKA	97	2
PKB alpha	81	2
PKB beta	84	9
PKC alpha	86	3
PKC zeta	87	9
PKD1	95	1
PLK1	91	1
PRAK	94	2
PRK2	91	2
RIPK2	77	11
ROCK 2	83	3
RSK1	81	4
RSK2	83	6
S6K1	86	1
SGK1	85	3
SmMLCK	88	3
Src	92	8
SRPK1	93	0
SYK	84	8
TAK1	96	5
TAO1	81	3
TBK1	83	1
TrkA	85	1
TTK	81	3
VEGFR1	64	7
YES1	77	6

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	95	6
ASK1	101	6
Aurora A	91	6
Aurora B	89	7
BRSK1	94	3
BRSK2	100	1
BTK	92	0
CAMK1	88	13
CAMKK beta	61	7
CDK2-Cyclin A	73	3
CHK1	97	7
CHK2	67	7
CK1 delta	79	9
CK2	69	6
CLK2	62	9
CSK	61	0
DAPK1	88	10
DYRK1A	93	5
DYRK2	99	9
DYRK3	88	6
EF2K	82	7
EPH-A2	44	1
EPH-A4	70	4
EPH-B1	90	4
EPH-B2	24	3
EPH-B3	24	0
EPH-B4	89	4
ERK1	86	11
ERK2	83	4
ERK8	72	4
FGF-R1	76	5
GCK	83	2
GSK3 beta	75	0
HER4	46	4
HIPK1	84	8
HIPK2	70	6
HIPK3	105	1
IGF-1R	80	1
IKK beta	74	8
IKK epsilon	70	6
IR	62	9
IRAK4	88	8
IRR	87	8
JAK2	85	6
JNK1	90	7
JNK2	85	0
JNK3	79	1
Lck	7	1
LKB1	85	5
MAPKAP-K2	93	10
MAPKAP-K3	93	4
MARK1	92	10
MARK2	97	7
MARK3	105	6
MARK4	100	2
MEKK1	99	9
MELK	40	3
MINK1	63	10
MKK1	94	11
MKK2	104	5
MKK6	98	9
MLK1	71	0
MLK3	74	10
MNK1	95	2
MNK2	85	6
MSK1	86	5
MST2	78	2
MST4	102	3
NEK2a	110	5
NEK6	90	0
NUAK1	54	5
p38 alpha MAPK	106	2
p38 beta MAPK	82	2
p38 delta MAPK	81	2
p38 gamma MAPK	97	4
PAK2	102	13
PAK4	92	12
PAK5	95	0
PAK6	89	11
PDK1	102	5
PHK	86	12
PIM1	68	4
PIM2	88	2
PIM3	61	3
PKA	105	2
PKB alpha	77	4
PKB beta	86	12
PKC alpha	92	5
PKC zeta	96	6
PKD1	91	5
PLK1	88	1
PRAK	99	0
PRK2	95	7
RIPK2	39	2
ROCK 2	94	9
RSK1	83	8
RSK2	83	14
S6K1	87	13
SGK1	89	0
SmMLCK	85	10
Src	75	6
SRPK1	101	10
SYK	70	8
TAK1	81	1
TAO1	75	1
TBK1	77	4
TrkA	52	8
TTK	80	2
VEGFR1	56	7
YES1	49	5