Inhibitor | Curcumin  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
DYRK2	2	1
PHK	2	0
DYRK1A	3	0
DYRK3	4	4
MLK3	6	0
CLK2	7	0
GCK	7	1
RIPK2	10	4
HIPK2	11	5
ERK8	11	0
PIM1	12	0
MINK1	12	3
PIM3	12	1
RSK1	15	0
CHK2	16	1
PKB beta	17	1
PIM2	17	0
MLK1	17	1
VEGFR1	18	4
IKK epsilon	21	0
IRR	24	0
CAMK1	24	4
TrkA	25	3
CAMKK beta	26	1
Aurora A	26	5
TTK	28	1
RSK2	29	1
S6K1	30	3
YES1	31	3
FGF-R1	31	6
IRAK4	35	1
HIPK3	35	2
BTK	37	4
MELK	38	0
MEKK1	38	3
HER4	39	4
MST2	39	1
SRPK1	39	4
NUAK1	40	3
SmMLCK	40	3
TAO1	42	2
DAPK1	42	1
PKC alpha	43	2
HIPK1	44	2
TAK1	46	1
ROCK 2	50	4
JAK2	53	1
IR	54	4
MAPKAP-K3	56	2
MARK2	57	0
PRAK	57	6
Aurora B	57	3
Lck	58	4
CDK2-Cyclin A	59	6
IGF-1R	60	8
PAK4	61	2
TBK1	61	2
SYK	62	1
CK2	63	5
PAK5	63	4
PKD1	63	12
GSK3 beta	65	8
PRK2	65	0
CSK	66	4
p38 beta MAPK	68	2
MARK1	68	3
PAK2	69	0
MARK3	70	1
EPH-A4	72	2
LKB1	72	3
EPH-A2	72	1
BRSK1	75	3
EPH-B3	75	13
PDK1	78	7
Src	78	13
BRSK2	78	8
MSK1	78	6
MKK1	78	9
MNK1	78	11
MNK2	79	8
SGK1	79	1
ERK2	80	9
ERK1	80	6
AMPK	81	9
NEK2a	82	7
MARK4	83	7
EPH-B2	83	2
PKB alpha	83	4
PKA	85	1
MST4	86	2
NEK6	88	12
EF2K	89	2
PKC zeta	90	11
CHK1	90	12
p38 delta MAPK	92	5
JNK3	93	7
MAPKAP-K2	94	1
IKK beta	95	6
p38 gamma MAPK	96	0
CK1 delta	96	10
PLK1	97	4
JNK1	98	5
PAK6	99	13
MKK2	100	11
p38 alpha MAPK	102	12
JNK2	107	0
MKK6	112	6
EPH-B1	116	8
EPH-B4	120	1
ASK1	120	4

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
DYRK2	3	1
DYRK3	5	1
MLK3	6	3
PHK	10	1
RIPK2	14	3
PIM3	18	3
DYRK1A	25	1
MLK1	33	3
CLK2	38	1
IRR	39	3
HIPK2	41	2
MINK1	42	5
GCK	43	5
PIM1	48	1
VEGFR1	48	1
YES1	53	4
CAMKK beta	54	1
IGF-1R	55	3
TTK	59	1
MELK	61	5
PIM2	63	3
ERK8	63	9
HER4	64	4
RSK1	66	2
CHK2	68	10
HIPK3	73	10
TAO1	75	3
S6K1	76	3
PAK5	76	9
SmMLCK	77	7
BTK	78	0
SRPK1	80	4
p38 gamma MAPK	81	5
CAMK1	81	1
Aurora B	81	10
JNK3	82	5
PAK2	82	2
PKC alpha	82	12
NEK6	83	4
MEKK1	83	1
PKB beta	84	5
IRAK4	85	2
TrkA	85	6
HIPK1	85	10
EF2K	86	1
MARK3	87	10
ERK1	87	3
NUAK1	87	7
DAPK1	87	14
CK2	88	6
p38 beta MAPK	88	13
MARK2	88	10
MAPKAP-K3	88	3
Aurora A	88	2
MNK1	89	1
IKK epsilon	89	2
LKB1	90	2
FGF-R1	91	2
PRAK	91	3
TBK1	91	3
EPH-A2	92	5
CDK2-Cyclin A	93	1
MST4	93	5
MARK1	95	6
IR	95	6
MARK4	95	10
PAK4	95	9
Lck	95	0
EPH-A4	95	7
PLK1	96	4
CSK	97	4
MST2	97	15
SGK1	98	1
SYK	98	5
EPH-B2	99	5
ROCK 2	99	1
PRK2	99	4
PAK6	99	2
PKD1	101	3
MAPKAP-K2	102	3
TAK1	102	6
RSK2	102	11
NEK2a	102	3
PKA	102	3
BRSK1	102	0
Src	103	10
MNK2	104	1
JAK2	104	7
JNK1	105	0
JNK2	105	13
PKB alpha	106	1
CHK1	106	0
MKK2	106	7
GSK3 beta	106	7
AMPK	106	12
EPH-B3	107	5
MSK1	107	4
EPH-B1	107	1
p38 alpha MAPK	108	11
CK1 delta	108	3
MKK6	109	10
ERK2	109	14
IKK beta	109	5
ASK1	110	3
PDK1	110	11
BRSK2	111	2
EPH-B4	111	4
PKC zeta	118	9
p38 delta MAPK	122	5
MKK1	122	2