Inhibitor | Curcumin  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	106	12
ASK1	110	3
Aurora A	88	2
Aurora B	81	10
BRSK1	102	0
BRSK2	111	2
BTK	78	0
CAMK1	81	1
CAMKK beta	54	1
CDK2-Cyclin A	93	1
CHK1	106	0
CHK2	68	10
CK1 delta	108	3
CK2	88	6
CLK2	38	1
CSK	97	4
DAPK1	87	14
DYRK1A	25	1
DYRK2	3	1
DYRK3	5	1
EF2K	86	1
EPH-A2	92	5
EPH-A4	95	7
EPH-B1	107	1
EPH-B2	99	5
EPH-B3	107	5
EPH-B4	111	4
ERK1	87	3
ERK2	109	14
ERK8	63	9
FGF-R1	91	2
GCK	43	5
GSK3 beta	106	7
HER4	64	4
HIPK1	85	10
HIPK2	41	2
HIPK3	73	10
IGF-1R	55	3
IKK beta	109	5
IKK epsilon	89	2
IR	95	6
IRAK4	85	2
IRR	39	3
JAK2	104	7
JNK1	105	0
JNK2	105	13
JNK3	82	5
Lck	95	0
LKB1	90	2
MAPKAP-K2	102	3
MAPKAP-K3	88	3
MARK1	95	6
MARK2	88	10
MARK3	87	10
MARK4	95	10
MEKK1	83	1
MELK	61	5
MINK1	42	5
MKK1	122	2
MKK2	106	7
MKK6	109	10
MLK1	33	3
MLK3	6	3
MNK1	89	1
MNK2	104	1
MSK1	107	4
MST2	97	15
MST4	93	5
NEK2a	102	3
NEK6	83	4
NUAK1	87	7
p38 alpha MAPK	108	11
p38 beta MAPK	88	13
p38 delta MAPK	122	5
p38 gamma MAPK	81	5
PAK2	82	2
PAK4	95	9
PAK5	76	9
PAK6	99	2
PDK1	110	11
PHK	10	1
PIM1	48	1
PIM2	63	3
PIM3	18	3
PKA	102	3
PKB alpha	106	1
PKB beta	84	5
PKC alpha	82	12
PKC zeta	118	9
PKD1	101	3
PLK1	96	4
PRAK	91	3
PRK2	99	4
RIPK2	14	3
ROCK 2	99	1
RSK1	66	2
RSK2	102	11
S6K1	76	3
SGK1	98	1
SmMLCK	77	7
Src	103	10
SRPK1	80	4
SYK	98	5
TAK1	102	6
TAO1	75	3
TBK1	91	3
TrkA	85	6
TTK	59	1
VEGFR1	48	1
YES1	53	4

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	81	9
ASK1	120	4
Aurora A	26	5
Aurora B	57	3
BRSK1	75	3
BRSK2	78	8
BTK	37	4
CAMK1	24	4
CAMKK beta	26	1
CDK2-Cyclin A	59	6
CHK1	90	12
CHK2	16	1
CK1 delta	96	10
CK2	63	5
CLK2	7	0
CSK	66	4
DAPK1	42	1
DYRK1A	3	0
DYRK2	2	1
DYRK3	4	4
EF2K	89	2
EPH-A2	72	1
EPH-A4	72	2
EPH-B1	116	8
EPH-B2	83	2
EPH-B3	75	13
EPH-B4	120	1
ERK1	80	6
ERK2	80	9
ERK8	11	0
FGF-R1	31	6
GCK	7	1
GSK3 beta	65	8
HER4	39	4
HIPK1	44	2
HIPK2	11	5
HIPK3	35	2
IGF-1R	60	8
IKK beta	95	6
IKK epsilon	21	0
IR	54	4
IRAK4	35	1
IRR	24	0
JAK2	53	1
JNK1	98	5
JNK2	107	0
JNK3	93	7
Lck	58	4
LKB1	72	3
MAPKAP-K2	94	1
MAPKAP-K3	56	2
MARK1	68	3
MARK2	57	0
MARK3	70	1
MARK4	83	7
MEKK1	38	3
MELK	38	0
MINK1	12	3
MKK1	78	9
MKK2	100	11
MKK6	112	6
MLK1	17	1
MLK3	6	0
MNK1	78	11
MNK2	79	8
MSK1	78	6
MST2	39	1
MST4	86	2
NEK2a	82	7
NEK6	88	12
NUAK1	40	3
p38 alpha MAPK	102	12
p38 beta MAPK	68	2
p38 delta MAPK	92	5
p38 gamma MAPK	96	0
PAK2	69	0
PAK4	61	2
PAK5	63	4
PAK6	99	13
PDK1	78	7
PHK	2	0
PIM1	12	0
PIM2	17	0
PIM3	12	1
PKA	85	1
PKB alpha	83	4
PKB beta	17	1
PKC alpha	43	2
PKC zeta	90	11
PKD1	63	12
PLK1	97	4
PRAK	57	6
PRK2	65	0
RIPK2	10	4
ROCK 2	50	4
RSK1	15	0
RSK2	29	1
S6K1	30	3
SGK1	79	1
SmMLCK	40	3
Src	78	13
SRPK1	39	4
SYK	62	1
TAK1	46	1
TAO1	42	2
TBK1	61	2
TrkA	25	3
TTK	28	1
VEGFR1	18	4
YES1	31	3