Inhibitor | MLi-2  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	103	7
AMPK (hum)	100	5
ASK1	52	6
Aurora A	104	3
Aurora B	100	3
BRK	125	0
BRSK1	105	1
BRSK2	101	10
BTK	91	3
CAMK1	78	3
CAMKK beta	73	8
CDK2-Cyclin A	124	3
CDK9-Cyclin T1	96	11
CHK1	106	4
CHK2	81	3
CK1 delta	102	15
CK1 gamma 2	107	0
CK2	102	1
CLK2	17	1
CSK	119	8
DAPK1	92	3
DDR2	109	15
DYRK1A	87	19
DYRK2	95	10
DYRK3	109	6
EF2K	98	3
EIF2AK3	116	4
EPH-A2	114	14
EPH-A4	104	2
EPH-B1	111	2
EPH-B2	118	9
EPH-B3	105	4
EPH-B4	92	3
ERK1	94	2
ERK2	103	1
ERK5	77	5
ERK8	93	5
FGF-R1	85	3
GCK	99	1
GSK3 beta	102	4
HER4	127	12
HIPK1	104	5
HIPK2	113	3
HIPK3	115	11
IGF-1R	109	9
IKK beta	102	12
IKK epsilon	99	9
IR	119	12
IRAK1	89	1
IRAK4	93	5
IRR	114	7
JAK2	109	4
JNK1	90	5
JNK2	93	9
JNK3	57	3
Lck	107	1
LKB1	117	7
MAP4K3	95	11
MAP4K5	98	2
MAPKAP-K2	110	7
MAPKAP-K3	121	6
MARK1	102	1
MARK2	97	12
MARK3	104	0
MARK4	101	9
MEKK1	103	2
MELK	102	1
MINK1	115	2
MKK1	93	7
MKK2	88	3
MKK6	109	0
MLK1	110	1
MLK3	110	8
MNK1	109	8
MNK2	114	18
MPSK1	112	4
MSK1	107	6
MST2	102	8
MST3	105	13
MST4	109	17
NEK2a	108	1
NEK6	103	8
NUAK1	53	3
OSR1	100	0
p38 alpha MAPK	106	6
p38 beta MAPK	104	0
p38 delta MAPK	113	7
p38 gamma MAPK	113	13
PAK2	100	11
PAK4	113	6
PAK5	95	2
PAK6	128	9
PDGFRA	118	2
PDK1	124	3
PHK	88	1
PIM1	103	4
PIM2	108	4
PIM3	96	15
PINK	109	0
PKA	113	3
PKB alpha	107	6
PKB beta	108	10
PKC alpha	114	3
PKC gamma	109	9
PKC zeta	110	6
PKD1	94	11
PLK1	123	5
PRAK	85	4
PRK2	111	0
RIPK2	119	8
ROCK 2	110	2
RSK1	90	4
RSK2	104	2
S6K1	95	5
SGK1	115	12
SIK2	103	6
SIK3	95	4
SmMLCK	100	0
Src	90	3
SRPK1	94	13
STK33	77	1
SYK	108	2
TAK1	90	2
TAO1	105	9
TBK1	118	12
TESK1	92	9
TGFBR1	118	6
TIE2	106	7
TLK1	106	13
TrkA	106	7
TSSK1	47	3
TTBK1	102	3
TTBK2	94	19
TTK	84	10
ULK1	105	1
ULK2	105	2
VEGFR1	115	18
WNK1	120	0
YES1	93	12
ZAP70	115	15

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	97	3
AMPK (hum)	48	11
ASK1	20	1
Aurora A	103	7
Aurora B	68	1
BRK	114	5
BRSK1	79	8
BRSK2	86	8
BTK	102	2
CAMK1	24	4
CAMKK beta	39	13
CDK2-Cyclin A	91	2
CDK9-Cyclin T1	100	10
CHK1	106	8
CHK2	26	4
CK1 delta	101	2
CK1 gamma 2	104	7
CK2	116	10
CLK2	2	1
CSK	122	3
DAPK1	54	0
DDR2	97	1
DYRK1A	52	5
DYRK2	59	2
DYRK3	94	1
EF2K	100	8
EIF2AK3	115	7
EPH-A2	122	7
EPH-A4	92	4
EPH-B1	94	11
EPH-B2	136	14
EPH-B3	127	18
EPH-B4	94	7
ERK1	56	11
ERK2	66	3
ERK5	40	4
ERK8	75	8
FGF-R1	78	3
GCK	51	14
GSK3 beta	105	2
HER4	131	0
HIPK1	104	7
HIPK2	93	7
HIPK3	98	3
IGF-1R	110	6
IKK beta	108	7
IKK epsilon	99	2
IR	121	7
IRAK1	87	4
IRAK4	92	1
IRR	91	6
JAK2	109	4
JNK1	41	5
JNK2	43	10
JNK3	17	6
Lck	113	15
LKB1	110	2
MAP4K3	89	3
MAP4K5	88	3
MAPKAP-K2	102	3
MAPKAP-K3	120	14
MARK1	102	1
MARK2	106	11
MARK3	113	9
MARK4	109	8
MEKK1	103	14
MELK	55	8
MINK1	100	14
MKK1	73	7
MKK2	78	12
MKK6	100	5
MLK1	56	4
MLK3	95	7
MNK1	89	4
MNK2	69	3
MPSK1	115	4
MSK1	111	6
MST2	116	5
MST3	110	5
MST4	111	2
NEK2a	115	16
NEK6	112	3
NUAK1	16	3
OSR1	64	1
p38 alpha MAPK	108	10
p38 beta MAPK	108	7
p38 delta MAPK	112	8
p38 gamma MAPK	115	4
PAK2	105	6
PAK4	108	13
PAK5	102	10
PAK6	110	1
PDGFRA	85	6
PDK1	109	5
PHK	39	1
PIM1	61	3
PIM2	97	4
PIM3	49	7
PINK	107	13
PKA	114	13
PKB alpha	109	7
PKB beta	115	5
PKC alpha	106	3
PKC gamma	100	0
PKC zeta	88	6
PKD1	50	6
PLK1	114	7
PRAK	31	8
PRK2	111	7
RIPK2	116	3
ROCK 2	108	2
RSK1	60	4
RSK2	75	12
S6K1	103	1
SGK1	99	1
SIK2	106	9
SIK3	105	7
SmMLCK	36	0
Src	99	19
SRPK1	71	3
STK33	31	4
SYK	102	3
TAK1	53	9
TAO1	120	14
TBK1	99	1
TESK1	94	4
TGFBR1	115	1
TIE2	97	13
TLK1	100	1
TrkA	53	3
TSSK1	13	3
TTBK1	94	7
TTBK2	100	10
TTK	53	4
ULK1	94	11
ULK2	89	1
VEGFR1	109	18
WNK1	116	5
YES1	109	21
ZAP70	114	1