Inhibitor | QNZ  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	111	4
AMPK (hum)	114	8
ASK1	135	25
Aurora A	100	12
Aurora B	88	14
BRK	99	7
BRSK1	111	9
BRSK2	86	7
BTK	88	10
CAMK1	101	14
CAMKK beta	99	4
CDK2-Cyclin A	114	11
CDK9-Cyclin T1	82	9
CHK1	87	8
CHK2	81	3
CK1 delta	93	2
CK1 gamma 2	98	1
CK2	97	2
CLK2	101	18
CSK	96	6
DAPK1	104	17
DDR2	112	4
DYRK1A	88	2
DYRK2	89	3
DYRK3	101	15
EF2K	115	4
EIF2AK3	97	8
EPH-A2	90	7
EPH-A4	102	11
EPH-B1	96	25
EPH-B2	104	0
EPH-B3	98	10
EPH-B4	113	11
ERK1	100	3
ERK2	107	4
ERK5	99	6
ERK8	99	4
FGF-R1	106	5
GCK	102	2
GSK3 beta	87	10
HER4	23	10
HIPK1	96	13
HIPK2	95	7
HIPK3	125	1
IGF-1R	119	32
IKK beta	94	7
IKK epsilon	92	3
IR	89	3
IRAK1	94	4
IRAK4	93	0
IRR	122	2
JAK2	93	9
JNK1	79	10
JNK2	97	1
JNK3	93	11
Lck	63	33
LKB1	87	8
MAP4K3	103	25
MAP4K5	100	2
MAPKAP-K2	108	4
MAPKAP-K3	97	5
MARK1	89	2
MARK2	98	2
MARK3	110	38
MARK4	90	3
MEKK1	86	26
MELK	86	13
MINK1	118	11
MKK1	119	13
MKK2	75	14
MKK6	92	5
MLK1	84	6
MLK3	98	16
MNK1	112	6
MNK2	96	6
MPSK1	102	4
MSK1	92	16
MST2	110	5
MST3	96	13
MST4	99	6
NEK2a	89	5
NEK6	98	4
NUAK1	96	5
OSR1	107	8
p38 alpha MAPK	100	23
p38 beta MAPK	106	1
p38 delta MAPK	98	16
p38 gamma MAPK	106	1
PAK2	89	5
PAK4	94	10
PAK5	102	10
PAK6	89	3
PDGFRA	93	8
PDK1	105	17
PHK	95	9
PIM1	94	7
PIM2	101	2
PIM3	103	8
PINK	106	5
PKA	107	4
PKB alpha	109	7
PKB beta	87	1
PKC alpha	98	7
PKC gamma	79	22
PKC zeta	94	7
PKD1	105	15
PLK1	106	5
PRAK	96	7
PRK2	115	5
RIPK2	104	4
ROCK 2	87	1
RSK1	99	2
RSK2	85	14
S6K1	109	10
SGK1	99	28
SIK2	101	8
SIK3	88	9
SmMLCK	102	19
Src	74	10
SRPK1	95	9
STK33	101	2
SYK	105	7
TAK1	90	3
TAO1	102	5
TBK1	114	4
TESK1	111	34
TGFBR1	106	14
TIE2	109	11
TLK1	100	1
TrkA	139	47
TSSK1	94	6
TTBK1	84	8
TTBK2	119	39
TTK	86	6
ULK1	111	2
ULK2	102	4
VEGFR1	96	13
WNK1	98	4
YES1	97	5
ZAP70	134	5

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	114	3
AMPK (hum)	112	23
ASK1	122	8
Aurora A	107	8
Aurora B	60	15
BRK	73	10
BRSK1	112	6
BRSK2	87	14
BTK	91	6
CAMK1	82	3
CAMKK beta	86	1
CDK2-Cyclin A	100	6
CDK9-Cyclin T1	99	8
CHK1	78	13
CHK2	44	2
CK1 delta	97	6
CK1 gamma 2	108	4
CK2	97	0
CLK2	88	2
CSK	84	1
DAPK1	90	1
DDR2	98	11
DYRK1A	82	2
DYRK2	88	2
DYRK3	100	5
EF2K	98	7
EIF2AK3	99	1
EPH-A2	104	1
EPH-A4	98	17
EPH-B1	95	9
EPH-B2	106	18
EPH-B3	110	21
EPH-B4	105	2
ERK1	85	0
ERK2	91	4
ERK5	99	3
ERK8	86	8
FGF-R1	96	0
GCK	64	8
GSK3 beta	90	4
HER4	16	2
HIPK1	98	7
HIPK2	99	6
HIPK3	74	4
IGF-1R	91	17
IKK beta	72	13
IKK epsilon	87	8
IR	102	23
IRAK1	87	16
IRAK4	72	3
IRR	100	0
JAK2	85	3
JNK1	86	5
JNK2	95	10
JNK3	80	3
Lck	72	6
LKB1	104	13
MAP4K3	95	19
MAP4K5	38	13
MAPKAP-K2	107	18
MAPKAP-K3	91	1
MARK1	87	3
MARK2	91	8
MARK3	87	15
MARK4	76	7
MEKK1	75	16
MELK	91	3
MINK1	101	12
MKK1	94	6
MKK2	72	7
MKK6	97	11
MLK1	57	4
MLK3	63	5
MNK1	114	5
MNK2	85	5
MPSK1	102	10
MSK1	92	14
MST2	103	3
MST3	98	10
MST4	118	2
NEK2a	89	4
NEK6	111	5
NUAK1	103	10
OSR1	108	12
p38 alpha MAPK	95	17
p38 beta MAPK	105	6
p38 delta MAPK	84	11
p38 gamma MAPK	101	7
PAK2	75	0
PAK4	86	14
PAK5	86	7
PAK6	92	6
PDGFRA	84	4
PDK1	104	4
PHK	80	2
PIM1	93	4
PIM2	88	8
PIM3	77	0
PINK	94	11
PKA	90	2
PKB alpha	93	8
PKB beta	92	2
PKC alpha	100	4
PKC gamma	98	27
PKC zeta	86	4
PKD1	86	4
PLK1	100	4
PRAK	87	7
PRK2	86	14
RIPK2	85	0
ROCK 2	73	3
RSK1	88	9
RSK2	71	6
S6K1	91	10
SGK1	88	2
SIK2	76	7
SIK3	74	15
SmMLCK	84	11
Src	50	2
SRPK1	98	9
STK33	93	2
SYK	89	1
TAK1	79	5
TAO1	101	9
TBK1	102	10
TESK1	97	14
TGFBR1	103	2
TIE2	88	2
TLK1	85	7
TrkA	81	9
TSSK1	86	7
TTBK1	93	12
TTBK2	124	10
TTK	76	2
ULK1	103	8
ULK2	91	1
VEGFR1	88	7
WNK1	95	4
YES1	65	3
ZAP70	102	6