Inhibitor | CHIR 99021 (CT 99021)  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	85	4
Aurora B	85	8
Aurora C	82	7
BRSK2	67	1
BTK	101	6
CAMK1	83	0
CAMKK alpha	89	3
CAMKK beta	84	2
CDK2-Cyclin A	53	3
CHK1	97	2
CHK2	93	3
CK1 delta	85	3
CK2	71	2
CSK	66	0
DYRK1A	81	9
DYRK2	87	2
DYRK3	66	2
EF2K	99	1
EPH-A2	106	15
EPH-B3	130	15
ERK1	77	2
ERK2	89	6
ERK8	90	1
FGF-R1	127	42
GSK3 beta	1	1
HIPK2	84	3
HIPK3	89	0
IGF-1R	66	2
IKK beta	87	8
IKK epsilon	85	1
IR	109	7
IRR	95	4
JNK1	84	8
JNK2	87	3
JNK3	70	3
Lck	88	3
MAPKAP-K2	110	3
MAPKAP-K3	70	7
MARK3	91	8
MELK	45	5
MKK1	70	3
MNK1	81	6
MNK2	85	8
MSK1	83	9
MST2	79	6
MST4	91	8
NEK2a	83	0
NEK6	89	5
NEK7	84	0
p38 alpha MAPK	82	9
p38 beta MAPK	87	3
p38 delta MAPK	100	6
p38 gamma MAPK	101	6
PAK4	74	1
PAK5	80	2
PAK6	84	0
PDK1	85	0
PHK	75	1
PIM1	70	1
PIM2	63	0
PIM3	64	4
PKA	89	0
PKB alpha	105	0
PKB beta	80	5
PKC alpha	78	8
PKC zeta	90	1
PKD1	75	8
PLK1	50	1
PRAK	76	7
PRK2	93	1
ROCK 2	79	3
RSK1	65	8
RSK2	88	6
S6K1	84	2
SGK1	78	4
SmMLCK	82	1
Src	83	1
SRPK1	81	5
SYK	97	20
TBK1	98	8
VEGFR1	86	3
YES1	100	3

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	36	2
Aurora B	61	4
Aurora C	62	2
BRSK2	58	4
CAMK1	88	2
CAMKK alpha	49	7
CAMKK beta	68	6
CDK2-Cyclin A	28	4
CHK1	80	5
CHK2	90	2
CK1 delta	71	8
CK2	74	8
CSK	74	2
DYRK1A	47	5
DYRK2	75	2
DYRK3	65	7
EF2K	84	4
ERK1	105	0
ERK2	97	4
ERK8	65	5
GSK3 beta	1	1
HIPK2	68	1
HIPK3	86	5
IKK beta	55	0
JNK1	75	7
JNK2	66	6
JNK3	81	0
Lck	66	5
MAPKAP-K2	88	5
MAPKAP-K3	103	0
MARK3	82	0
MELK	16	1
MKK1	75	3
MNK1	74	3
MNK2	86	5
MSK1	50	0
MST2	57	9
NEK2a	70	7
NEK6	88	1
NEK7	104	2
p38 alpha MAPK	93	6
p38 beta MAPK	91	4
p38 delta MAPK	65	4
p38 gamma MAPK	87	6
PAK4	77	1
PAK5	80	2
PAK6	84	4
PDK1	81	7
PHK	82	1
PIM1	58	3
PIM2	54	6
PIM3	63	0
PKA	75	3
PKB alpha	112	0
PKB beta	73	7
PKC alpha	10	0
PKC zeta	71	6
PKD1	46	1
PLK1	37	0
PRAK	60	1
PRK2	82	4
ROCK 2	90	0
RSK1	78	1
RSK2	85	3
S6K1	101	3
SGK1	69	4
SmMLCK	64	7
Src	62	1
SRPK1	62	4