Inhibitor | Metformin  

Screen Conc: 100.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
EPH-B4	63	5
SYK	74	10
MINK1	74	9
JNK2	75	1
Aurora B	76	4
HER4	77	17
BTK	78	32
CDK9-Cyclin T1	78	7
MKK6	79	3
FGF-R1	79	2
p38 alpha MAPK	80	1
TrkA	80	11
NUAK1	81	16
TBK1	81	4
TSSK1	81	4
BRK	81	1
EPH-A2	81	4
BRSK2	81	0
EPH-B1	82	5
SRPK1	82	3
EIF2AK3	82	1
MLK3	83	1
RSK2	84	3
p38 gamma MAPK	85	3
JAK2	85	3
ERK8	85	8
IKK epsilon	86	6
EF2K	86	0
CAMK1	86	10
GCK	87	4
MPSK1	87	3
Src	87	8
TAO1	87	14
ERK5	87	1
PKC gamma	88	9
GSK3 beta	88	7
MST3	88	2
RSK1	88	11
CK2	88	1
SGK1	88	1
CSK	88	1
BRSK1	88	1
NEK6	88	34
PKD1	89	0
p38 delta MAPK	89	4
PIM3	89	1
CK1 delta	89	2
ZAP70	89	1
VEGFR1	89	6
DYRK1A	89	18
ROCK 2	89	4
EPH-A4	89	10
SIK2	90	1
PDK1	90	6
TLK1	90	5
HIPK1	90	1
TIE2	90	7
JNK1	90	8
MKK1	90	6
CK1 gamma 2	91	9
MAP4K5	91	15
MAPKAP-K3	91	7
TTBK2	91	4
DYRK2	91	9
PAK4	91	19
DAPK1	91	1
MSK1	92	11
WNK1	92	20
MNK1	92	3
MEKK1	92	6
MLK1	92	3
AMPK (hum)	92	5
CAMKK beta	92	7
JNK3	92	14
EPH-B3	93	2
ULK1	93	3
MAPKAP-K2	93	1
TGFBR1	93	2
TTBK1	93	5
MARK1	93	12
SmMLCK	93	1
CHK1	93	1
STK33	94	9
SIK3	94	10
MAP4K3	94	17
HIPK2	94	1
CLK2	94	12
PKA	94	9
MARK4	94	9
RIPK2	95	4
ERK1	95	2
PLK1	95	8
LKB1	95	26
MARK3	95	8
IR	95	4
CDK2-Cyclin A	96	2
ERK2	96	1
PKB beta	96	4
HIPK3	96	8
TESK1	96	1
PINK	96	6
YES1	96	14
TAK1	96	1
PRK2	96	3
ABL	96	2
CHK2	97	4
IRR	97	2
OSR1	97	16
MST4	97	7
PDGFRA	97	3
Lck	97	10
S6K1	97	6
DYRK3	97	4
IKK beta	97	0
MKK2	98	9
MNK2	98	11
MARK2	98	4
PAK2	98	1
ASK1	98	0
EPH-B2	99	1
MELK	100	14
p38 beta MAPK	101	6
PKB alpha	101	2
Aurora A	102	7
PAK5	102	6
PIM1	103	1
PIM2	103	15
PHK	103	6
PKC zeta	104	7
PRAK	104	7
ULK2	106	6
NEK2a	106	9
MST2	107	13
PAK6	107	9
TTK	108	6
DDR2	109	10
IRAK1	111	3
PKC alpha	118	24
IGF-1R	129	7
IRAK4	134	59

Screen Conc: 250.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
JAK2	73	5
BTK	74	27
MINK1	75	4
EPH-B4	77	3
TrkA	78	11
MKK1	78	10
MKK6	78	1
SYK	80	5
HER4	81	0
FGF-R1	82	4
IKK epsilon	82	3
TIE2	82	10
Aurora B	83	5
MLK3	83	2
RSK2	83	1
DYRK2	84	3
NEK6	84	7
Src	86	3
TESK1	86	7
CAMK1	86	5
TBK1	86	4
MAP4K3	87	1
p38 gamma MAPK	87	11
CK1 delta	87	3
EIF2AK3	87	5
SIK3	87	5
CAMKK beta	88	4
PAK4	88	1
MEKK1	89	11
Lck	89	1
CLK2	89	3
VEGFR1	89	4
TSSK1	90	0
PIM3	90	4
TTBK2	90	10
BRK	90	2
SmMLCK	91	3
PAK5	91	8
PKC alpha	91	5
TTBK1	92	3
CSK	92	3
JNK2	92	7
PDGFRA	92	1
CDK9-Cyclin T1	92	0
MNK2	93	3
HIPK1	93	8
DYRK1A	93	2
MARK4	93	2
DAPK1	93	1
CHK1	93	2
BRSK2	93	1
CHK2	93	2
ZAP70	93	0
p38 alpha MAPK	93	8
GSK3 beta	93	14
NUAK1	93	18
ERK5	94	2
MARK1	94	3
RSK1	94	13
ROCK 2	94	2
ABL	94	11
IR	94	4
PKD1	94	6
PIM1	94	1
EPH-A4	95	10
MNK1	95	3
SRPK1	95	1
MAP4K5	95	10
MAPKAP-K3	95	12
MARK3	95	17
PRK2	95	6
BRSK1	95	4
PAK6	95	10
MELK	95	1
GCK	95	1
MPSK1	95	4
TLK1	96	4
YES1	96	17
IKK beta	96	6
SIK2	96	3
WNK1	97	14
ULK1	97	10
PKA	97	4
AMPK (hum)	97	9
ASK1	97	1
IRR	97	7
EPH-B1	98	5
IRAK4	98	3
PKB alpha	98	1
MST3	98	1
JNK1	99	2
DDR2	99	6
PKC zeta	99	6
OSR1	99	6
PIM2	99	13
Aurora A	100	5
ERK2	100	11
CK2	100	4
TGFBR1	100	11
PRAK	100	5
PHK	100	3
JNK3	100	8
PDK1	100	6
p38 beta MAPK	100	4
STK33	100	11
EF2K	101	5
p38 delta MAPK	101	5
ERK8	101	2
MARK2	101	3
NEK2a	101	5
TAK1	101	10
MKK2	101	13
ERK1	102	10
SGK1	102	1
S6K1	102	2
EPH-B3	103	4
PAK2	103	9
PKC gamma	103	9
MSK1	104	7
CK1 gamma 2	104	10
TAO1	104	7
EPH-A2	104	24
MLK1	106	17
MAPKAP-K2	107	17
HIPK3	107	12
RIPK2	107	4
MST4	107	11
TTK	108	14
PINK	108	3
PKB beta	108	4
DYRK3	109	5
ULK2	110	2
IRAK1	111	3
EPH-B2	112	8
HIPK2	112	18
MST2	112	5
LKB1	113	7
CDK2-Cyclin A	113	0
IGF-1R	122	5
PLK1	128	11