Inhibitor | BX-912  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
BX-912   C20H23BrN8O 471.35 702674-56-4 11754511 PDK Feldman RI. (2005) J. Biol. Chem. 2005 May 20 280(20) 19867-74

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
NUAK1
1
 0
VEGFR1
2
 0
MLK1
2
 0
Aurora B
2
 1
SIK2
2
 1
MARK3
4
 1
AMPK (hum)
5
 1
MARK4
7
 1
PDK1
8
 0
ERK8
8
 2
FGF-R1
9
 2
MARK1
10
 0
IRAK4
10
 1
JAK2
10
 2
SIK3 11 1
GCK 11 3
MLK3 11 5
CDK2-Cyclin A 12 4
MARK2 12 2
BRSK1 12 1
TBK1 12 3
BRSK2 13 0
Aurora A 14 3
CHK1 14 0
ULK1 15 1
TAK1 15 2
TrkA 17 5
CHK2 18 2
MAP4K3 18 2
CAMKK beta 18 0
MKK1 20 3
MKK2 20 3
SYK 21 4
IKK epsilon 24 1
CLK2 26 0
PDGFRA 29 5
PKA 30 1
MELK 30 3
MST2 31 2
PRK2 32 4
STK33 33 6
IR 34 7
MAP4K5 35 2
ABL 35 0
PKD1 37 1
BRK 39 2
BTK 40 7
ULK2 42 4
YES1 42 8
RSK1 42 0
Lck 43 3
TSSK1 45 5
IGF-1R 45 4
MNK2 45 2
RSK2 45 4
TAO1 46 8
ASK1 46 1
RIPK2 47 2
IRAK1 48 5
PHK 48 0
MST4 48 3
LKB1 49 6
MST3 49 3
MINK1 52 10
S6K1 52 4
Src 53 5
PAK4 54 4
MKK6 56 7
TIE2 58 13
JNK2 59 1
CDK9-Cyclin T1 60 7
SGK1 60 2
HIPK1 63 7
ERK5 63 8
ERK2 63 1
ERK1 67 5
HER4 69 21
DDR2 69 4
p38 delta MAPK 72 4
PKC alpha 73 20
IRR 73 6
PAK5 73 4
MSK1 74 11
JNK1 74 7
DYRK1A 75 8
ROCK 2 75 2
JNK3 76 0
DAPK1 76 9
TTK 76 5
PLK1 77 17
DYRK2 79 1
MNK1 79 2
EPH-B2 79 4
CK2 80 4
SmMLCK 80 5
GSK3 beta 81 0
PKB alpha 81 3
HIPK3 81 1
NEK2a 82 13
DYRK3 83 3
CK1 gamma 2 84 4
p38 gamma MAPK 84 3
p38 beta MAPK 85 3
PKC gamma 86 12
EPH-A4 86 3
CK1 delta 87 3
EPH-A2 87 9
PAK2 87 20
PAK6 87 10
ZAP70 88 2
CSK 88 9
PINK 88 4
TTBK2 89 6
CAMK1 89 9
OSR1 89 4
HIPK2 90 9
p38 alpha MAPK 91 3
PKB beta 91 11
TLK1 91 0
TGFBR1 92 6
TESK1 93 5
EIF2AK3 94 5
IKK beta 94 3
NEK6 95 17
SRPK1 96 13
MEKK1 97 1
MAPKAP-K3 98 4
EPH-B3 99 6
EF2K 101 30
PRAK 101 8
TTBK1 101 5
MAPKAP-K2 103 13
WNK1 104 4
PIM3 104 3
EPH-B4 104 10
PIM2 105 15
PIM1 105 5
MPSK1 105 2
EPH-B1 110 5
PKC zeta 118 6
Screen Conc: 0.10µM
Kinase % Activity Remaining Standard Deviation
NUAK1
2
 0
Aurora B
7
 2
SIK2
9
 0
VEGFR1
10
 0
MLK3 11 1
MLK1 16 0
MARK3 18 1
JAK2 27 0
AMPK (hum) 28 1
MARK4 32 5
GCK 39 7
TrkA 40 4
MARK1 41 4
SIK3 42 2
MARK2 42 5
ERK8 42 5
IRAK4 42 1
PDK1 43 9
BRSK1 44 1
TBK1 45 5
ULK1 48 6
FGF-R1 49 6
TAK1 49 1
CDK2-Cyclin A 50 1
BRSK2 50 6
CHK1 50 3
MST2 56 0
MKK2 57 5
Aurora A 62 9
RSK2 62 11
IKK epsilon 62 1
MKK1 63 3
PDGFRA 65 1
CAMKK beta 65 2
CHK2 67 5
PRK2 68 3
RIPK2 68 4
TSSK1 69 11
PKA 69 6
MAP4K5 70 2
MELK 72 8
MINK1 73 7
MKK6 74 12
SYK 74 16
MAP4K3 75 6
STK33 76 4
MST4 77 4
MST3 79 5
LKB1 79 4
IGF-1R 80 3
S6K1 80 2
PKD1 81 1
TAO1 81 2
YES1 82 7
RSK1 82 16
IR 82 25
PKC alpha 82 6
CLK2 82 1
ERK5 83 2
PINK 84 2
DYRK1A 84 8
TIE2 85 2
CDK9-Cyclin T1 86 6
p38 gamma MAPK 86 5
ABL 87 7
SGK1 87 1
HIPK1 87 14
TGFBR1 87 6
PKB alpha 87 1
GSK3 beta 87 15
SmMLCK 88 13
ERK1 88 3
BRK 89 0
PAK5 89 9
DDR2 89 5
Src 89 3
ERK2 89 3
EF2K 91 24
BTK 91 7
ULK2 91 9
CK1 delta 92 3
p38 beta MAPK 92 3
HIPK2 92 1
PAK4 93 3
CSK 93 9
CAMK1 93 11
JNK2 93 1
EPH-B2 93 11
HER4 94 9
PKB beta 94 10
TTBK1 94 3
HIPK3 94 4
MEKK1 94 6
Lck 95 16
TTK 95 10
MNK2 95 4
TLK1 95 10
SRPK1 96 3
p38 alpha MAPK 96 17
ASK1 96 2
MNK1 97 17
EIF2AK3 97 1
MAPKAP-K2 97 9
EPH-A4 98 14
DYRK3 99 5
CK1 gamma 2 99 14
p38 delta MAPK 99 33
PAK2 99 7
OSR1 100 12
EPH-A2 100 5
MSK1 100 8
DAPK1 100 2
IRAK1 100 1
ZAP70 100 3
DYRK2 101 5
NEK2a 101 13
JNK3 101 4
NEK6 101 1
PHK 101 6
JNK1 102 13
ROCK 2 102 5
TESK1 102 13
IRR 102 12
CK2 103 11
PAK6 104 21
EPH-B3 104 5
EPH-B4 104 4
PIM1 105 1
PIM2 105 4
PLK1 106 10
MAPKAP-K3 106 6
EPH-B1 109 1
TTBK2 109 25
PKC zeta 109 21
PKC gamma 110 3
IKK beta 111 6
WNK1 112 6
PRAK 112 8
PIM3 113 3
MPSK1 121 1