Inhibitor | KU55933  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
ABL	101	5
AMPK (hum)	65	8
ASK1	108	17
Aurora A	99	10
Aurora B	64	14
BRK	91	3
BRSK1	85	1
BRSK2	104	4
BTK	90	2
CAMK1	90	4
CAMKK beta	82	6
CDK2-Cyclin A	84	7
CDK9-Cyclin T1	88	2
CHK1	74	0
CHK2	97	0
CK1 delta	81	2
CK1 gamma 2	93	6
CK2	96	1
CLK2	93	1
CSK	112	17
DAPK1	98	2
DDR2	89	3
DYRK1A	76	6
DYRK2	89	1
DYRK3	100	2
EF2K	97	13
EIF2AK3	98	1
EPH-A2	104	12
EPH-A4	88	12
EPH-B1	98	4
EPH-B2	85	1
EPH-B3	91	5
EPH-B4	97	17
ERK1	94	3
ERK2	78	2
ERK5	88	1
ERK8	75	2
FGF-R1	91	14
GCK	85	16
GSK3 beta	94	4
HER4	96	6
HIPK1	79	7
HIPK2	84	11
HIPK3	82	4
IGF-1R	79	6
IKK beta	102	4
IKK epsilon	73	6
IR	77	12
IRAK1	87	7
IRAK4	80	1
IRR	98	7
JAK2	83	12
JNK1	83	0
JNK2	86	0
JNK3	108	25
Lck	86	4
LKB1	82	9
MAP4K3	82	5
MAP4K5	73	6
MAPKAP-K2	91	2
MAPKAP-K3	91	6
MARK1	69	3
MARK2	76	3
MARK3	62	10
MARK4	84	3
MEKK1	90	13
MELK	67	2
MINK1	71	4
MKK1	71	15
MKK2	70	2
MKK6	78	1
MLK1	81	11
MLK3	68	2
MNK1	99	4
MNK2	94	2
MPSK1	90	2
MSK1	97	8
MST2	64	5
MST3	68	8
MST4	79	0
NEK2a	100	1
NEK6	80	8
NUAK1	99	10
OSR1	89	5
p38 alpha MAPK	87	2
p38 beta MAPK	75	6
p38 delta MAPK	76	4
p38 gamma MAPK	67	14
PAK2	86	3
PAK4	119	17
PAK5	83	2
PAK6	88	6
PDGFRA	106	31
PDK1	93	8
PHK	110	21
PIM1	93	3
PIM2	108	14
PIM3	103	9
PINK	81	6
PKA	93	2
PKB alpha	73	2
PKB beta	87	5
PKC alpha	89	11
PKC gamma	95	4
PKC zeta	98	1
PKD1	95	4
PLK1	87	13
PRAK	94	6
PRK2	74	6
RIPK2	70	2
ROCK 2	82	5
RSK1	88	3
RSK2	74	6
S6K1	82	10
SGK1	94	2
SIK2	67	3
SIK3	72	5
SmMLCK	84	1
Src	85	15
SRPK1	87	8
STK33	95	5
SYK	89	1
TAK1	68	4
TAO1	79	9
TBK1	92	13
TESK1	85	2
TGFBR1	75	1
TIE2	85	16
TLK1	88	1
TrkA	94	2
TSSK1	72	2
TTBK1	87	2
TTBK2	94	9
TTK	86	4
ULK1	69	3
ULK2	84	5
VEGFR1	78	8
WNK1	88	6
YES1	85	5
ZAP70	95	5

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	101	6
AMPK (hum)	100	7
ASK1	100	17
Aurora A	95	7
Aurora B	69	6
BRK	81	3
BRSK1	94	10
BRSK2	94	10
BTK	84	6
CAMK1	91	3
CAMKK beta	93	6
CDK2-Cyclin A	94	9
CDK9-Cyclin T1	88	8
CHK1	82	10
CHK2	101	8
CK1 delta	79	1
CK1 gamma 2	62	3
CK2	99	1
CLK2	94	13
CSK	119	29
DAPK1	107	22
DDR2	95	3
DYRK1A	57	0
DYRK2	96	4
DYRK3	108	11
EF2K	90	2
EIF2AK3	99	6
EPH-A2	107	10
EPH-A4	101	12
EPH-B1	102	1
EPH-B2	88	2
EPH-B3	86	9
EPH-B4	98	9
ERK1	99	12
ERK2	88	1
ERK5	79	13
ERK8	63	2
FGF-R1	85	10
GCK	74	15
GSK3 beta	93	3
HER4	92	3
HIPK1	78	2
HIPK2	90	9
HIPK3	86	4
IGF-1R	84	2
IKK beta	102	8
IKK epsilon	77	3
IR	91	21
IRAK1	95	8
IRAK4	80	1
IRR	107	5
JAK2	96	6
JNK1	94	14
JNK2	86	14
JNK3	104	5
Lck	87	2
LKB1	79	3
MAP4K3	83	14
MAP4K5	74	3
MAPKAP-K2	95	2
MAPKAP-K3	98	2
MARK1	86	4
MARK2	92	9
MARK3	68	10
MARK4	94	10
MEKK1	95	9
MELK	89	12
MINK1	77	1
MKK1	90	7
MKK2	77	17
MKK6	75	9
MLK1	78	10
MLK3	79	13
MNK1	83	4
MNK2	102	4
MPSK1	101	7
MSK1	98	8
MST2	69	2
MST3	63	6
MST4	76	4
NEK2a	101	16
NEK6	87	4
NUAK1	99	9
OSR1	99	2
p38 alpha MAPK	92	10
p38 beta MAPK	87	18
p38 delta MAPK	83	1
p38 gamma MAPK	77	8
PAK2	93	8
PAK4	100	24
PAK5	87	4
PAK6	97	8
PDGFRA	102	13
PDK1	93	10
PHK	103	12
PIM1	86	5
PIM2	97	3
PIM3	73	0
PINK	78	4
PKA	94	0
PKB alpha	86	1
PKB beta	89	3
PKC alpha	103	11
PKC gamma	103	9
PKC zeta	96	3
PKD1	88	2
PLK1	89	10
PRAK	94	2
PRK2	85	0
RIPK2	63	2
ROCK 2	86	3
RSK1	92	1
RSK2	79	8
S6K1	85	2
SGK1	96	6
SIK2	83	2
SIK3	76	4
SmMLCK	82	8
Src	85	0
SRPK1	84	8
STK33	87	6
SYK	93	2
TAK1	83	3
TAO1	79	4
TBK1	81	0
TESK1	82	1
TGFBR1	80	9
TIE2	88	9
TLK1	98	5
TrkA	90	9
TSSK1	90	8
TTBK1	86	2
TTBK2	80	13
TTK	89	3
ULK1	74	10
ULK2	99	13
VEGFR1	83	9
WNK1	93	9
YES1	93	3
ZAP70	92	3