Inhibitor | Amlexanox  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
Amlexanox   C16H14N2O4 298.29 68302-57-8 2161 TBK1, IKKe

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ZAP70 98 4
YES1 74 7
WNK1 107 6
VEGFR1 49 4
ULK2 98 11
ULK1 77 6
TTK 82 2
TTBK2 98 7
TTBK1 95 3
TSSK1 96 5
TrkA 80 9
TLK1 106 4
TIE2 78 2
TGFBR1 110 16
TESK1 79 8
TBK1 73 9
TAO1 90 0
TAK1 103 13
SYK 81 12
STK33 94 11
SRPK1 58 3
Src 103 3
SmMLCK 53 7
SIK3 97 3
SIK2 87 8
SGK1 93 8
S6K1 79 10
RSK2 95 7
RSK1 87 5
ROCK 2 74 7
RIPK2 94 3
PRK2 106 3
PRAK 87 18
PLK1 98 3
PKD1 115 16
PKC zeta 102 6
PKC gamma 89 11
PKC alpha 91 10
PKB beta 87 0
PKB alpha 98 4
PKA 97 2
PINK 96 2
PIM3 53 4
PIM2 105 9
PIM1 91 7
PHK 108 4
PDK1 96 11
PDGFRA 106 2
PAK6 105 2
PAK5 93 4
PAK4 82 13
PAK2 105 8
p38 gamma MAPK 104 1
p38 delta MAPK 95 2
p38 beta MAPK 99 5
p38 alpha MAPK 119 3
OSR1 105 8
NUAK1 116 12
NEK6 103 1
NEK2a 92 8
MST4 82 6
MST3 73 6
MST2 85 1
MSK1 111 2
MPSK1 98 7
MNK2 89 0
MNK1 94 4
MLK3
10
 0
MLK1 18 1
MKK6 77 1
MKK2 90 3
MKK1 97 2
MINK1 85 3
MELK 91 7
MEKK1 100 8
MARK4 96 11
MARK3 86 10
MARK2 88 0
MARK1 87 12
MAPKAP-K3 84 8
MAPKAP-K2 97 10
MAP4K5 65 8
MAP4K3 84 0
LKB1 96 8
Lck 106 0
JNK3 94 1
JNK2 96 11
JNK1 84 2
JAK2 113 0
IRR 85 1
IRAK4 98 4
IRAK1 98 2
IR 98 4
IKK epsilon 84 16
IKK beta 104 12
IGF-1R 68 7
HIPK3 90 3
HIPK2 102 11
HIPK1 79 0
HER4 95 4
GSK3 beta 102 2
GCK 91 6
FGF-R1 102 13
ERK8 92 11
ERK5 99 2
ERK2 86 10
ERK1 109 15
EPH-B4 101 2
EPH-B3 74 7
EPH-B2 118 19
EPH-B1 91 5
EPH-A4 97 8
EPH-A2 104 16
EIF2AK3 93 7
EF2K 104 10
DYRK3 96 1
DYRK2 101 16
DYRK1A 74 5
DDR2 112 13
DAPK1 79 6
CSK 92 12
CLK2 91 12
CK2 84 14
CK1 gamma 2 77 4
CK1 delta 90 3
CHK2 47 4
CHK1 107 2
CDK9-Cyclin T1 108 3
CDK2-Cyclin A 92 8
CAMKK beta 94 4
CAMK1 108 25
BTK 84 5
BRSK2 102 5
BRSK1 110 3
BRK 66 7
Aurora B 83 9
Aurora A 98 7
ASK1 112 21
AMPK (hum) 89 8
AMPK 111 24
ABL 106 23
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ZAP70 109 7
YES1 94 10
WNK1 105 0
VEGFR1 15 0
ULK2 89 7
ULK1 93 8
TTK 67 0
TTBK2 86 8
TTBK1 107 12
TSSK1 86 2
TrkA 49 7
TLK1 109 2
TIE2 85 2
TGFBR1 98 10
TESK1 86 6
TBK1 22 0
TAO1 109 6
TAK1 86 6
SYK 79 10
STK33 79 5
SRPK1 16 1
Src 85 6
SmMLCK 13 1
SIK3 100 3
SIK2 84 2
SGK1 79 1
S6K1 69 2
RSK2 90 2
RSK1 70 1
ROCK 2 86 13
RIPK2 56 2
PRK2 113 25
PRAK 88 1
PLK1 92 3
PKD1 102 13
PKC zeta 85 8
PKC gamma 83 5
PKC alpha 98 4
PKB beta 82 8
PKB alpha 91 2
PKA 98 6
PINK 102 10
PIM3 14 0
PIM2 112 15
PIM1 67 1
PHK 95 1
PDK1 102 16
PDGFRA 84 12
PAK6 110 3
PAK5 102 7
PAK4 98 3
PAK2 109 2
p38 gamma MAPK 93 5
p38 delta MAPK 91 5
p38 beta MAPK 94 1
p38 alpha MAPK 103 9
OSR1 103 8
NUAK1 91 8
NEK6 108 0
NEK2a 97 10
MST4 89 11
MST3 92 11
MST2 84 4
MSK1 103 3
MPSK1 99 6
MNK2 91 4
MNK1 73 11
MLK3
5
 0
MLK1
6
 2
MKK6 103 8
MKK2 93 0
MKK1 102 12
MINK1 89 16
MELK 64 14
MEKK1 102 16
MARK4 85 6
MARK3 100 12
MARK2 94 4
MARK1 95 14
MAPKAP-K3 74 10
MAPKAP-K2 84 8
MAP4K5 46 0
MAP4K3 79 6
LKB1 122 30
Lck 102 10
JNK3 98 1
JNK2 98 3
JNK1 104 0
JAK2 74 0
IRR 53 1
IRAK4 97 16
IRAK1 83 2
IR 36 2
IKK epsilon 28 4
IKK beta 96 8
IGF-1R 31 0
HIPK3 93 4
HIPK2 93 23
HIPK1 82 1
HER4 73 8
GSK3 beta 96 10
GCK 87 2
FGF-R1 96 13
ERK8 79 4
ERK5 95 1
ERK2 96 4
ERK1 101 22
EPH-B4 88 6
EPH-B3 95 13
EPH-B2 105 3
EPH-B1 102 1
EPH-A4 71 3
EPH-A2 98 9
EIF2AK3 108 1
EF2K 102 12
DYRK3 93 7
DYRK2 79 17
DYRK1A 69 2
DDR2 90 4
DAPK1 43 12
CSK 81 7
CLK2 88 12
CK2 65 3
CK1 gamma 2 36 0
CK1 delta 85 4
CHK2 12 0
CHK1 113 1
CDK9-Cyclin T1 97 0
CDK2-Cyclin A 85 11
CAMKK beta 40 1
CAMK1 66 10
BTK 51 6
BRSK2 87 2
BRSK1 91 7
BRK 66 4
Aurora B 93 15
Aurora A 110 8
ASK1 116 6
AMPK (hum) 55 5
AMPK 113 16
ABL 86 12