Inhibitor | Amlexanox  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
Amlexanox   C16H14N2O4 298.29 68302-57-8 2161 TBK1, IKKe https://pubmed.ncbi.nlm.nih.gov/[pmid1] https://pubmed.ncbi.nlm.nih.gov/[pmid2]

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ABL 106 23
AMPK 111 24
AMPK (hum) 89 8
ASK1 112 21
Aurora A 98 7
Aurora B 83 9
BRK 66 7
BRSK1 110 3
BRSK2 102 5
BTK 84 5
CAMK1 108 25
CAMKK beta 94 4
CDK2-Cyclin A 92 8
CDK9-Cyclin T1 108 3
CHK1 107 2
CHK2 47 4
CK1 delta 90 3
CK1 gamma 2 77 4
CK2 84 14
CLK2 91 12
CSK 92 12
DAPK1 79 6
DDR2 112 13
DYRK1A 74 5
DYRK2 101 16
DYRK3 96 1
EF2K 104 10
EIF2AK3 93 7
EPH-A2 104 16
EPH-A4 97 8
EPH-B1 91 5
EPH-B2 118 19
EPH-B3 74 7
EPH-B4 101 2
ERK1 109 15
ERK2 86 10
ERK5 99 2
ERK8 92 11
FGF-R1 102 13
GCK 91 6
GSK3 beta 102 2
HER4 95 4
HIPK1 79 0
HIPK2 102 11
HIPK3 90 3
IGF-1R 68 7
IKK beta 104 12
IKK epsilon 84 16
IR 98 4
IRAK1 98 2
IRAK4 98 4
IRR 85 1
JAK2 113 0
JNK1 84 2
JNK2 96 11
JNK3 94 1
Lck 106 0
LKB1 96 8
MAP4K3 84 0
MAP4K5 65 8
MAPKAP-K2 97 10
MAPKAP-K3 84 8
MARK1 87 12
MARK2 88 0
MARK3 86 10
MARK4 96 11
MEKK1 100 8
MELK 91 7
MINK1 85 3
MKK1 97 2
MKK2 90 3
MKK6 77 1
MLK1 18 1
MLK3
10
0
MNK1 94 4
MNK2 89 0
MPSK1 98 7
MSK1 111 2
MST2 85 1
MST3 73 6
MST4 82 6
NEK2a 92 8
NEK6 103 1
NUAK1 116 12
OSR1 105 8
p38 alpha MAPK 119 3
p38 beta MAPK 99 5
p38 delta MAPK 95 2
p38 gamma MAPK 104 1
PAK2 105 8
PAK4 82 13
PAK5 93 4
PAK6 105 2
PDGFRA 106 2
PDK1 96 11
PHK 108 4
PIM1 91 7
PIM2 105 9
PIM3 53 4
PINK 96 2
PKA 97 2
PKB alpha 98 4
PKB beta 87 0
PKC alpha 91 10
PKC gamma 89 11
PKC zeta 102 6
PKD1 115 16
PLK1 98 3
PRAK 87 18
PRK2 106 3
RIPK2 94 3
ROCK 2 74 7
RSK1 87 5
RSK2 95 7
S6K1 79 10
SGK1 93 8
SIK2 87 8
SIK3 97 3
SmMLCK 53 7
Src 103 3
SRPK1 58 3
STK33 94 11
SYK 81 12
TAK1 103 13
TAO1 90 0
TBK1 73 9
TESK1 79 8
TGFBR1 110 16
TIE2 78 2
TLK1 106 4
TrkA 80 9
TSSK1 96 5
TTBK1 95 3
TTBK2 98 7
TTK 82 2
ULK1 77 6
ULK2 98 11
VEGFR1 49 4
WNK1 107 6
YES1 74 7
ZAP70 98 4
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ABL 86 12
AMPK 113 16
AMPK (hum) 55 5
ASK1 116 6
Aurora A 110 8
Aurora B 93 15
BRK 66 4
BRSK1 91 7
BRSK2 87 2
BTK 51 6
CAMK1 66 10
CAMKK beta 40 1
CDK2-Cyclin A 85 11
CDK9-Cyclin T1 97 0
CHK1 113 1
CHK2 12 0
CK1 delta 85 4
CK1 gamma 2 36 0
CK2 65 3
CLK2 88 12
CSK 81 7
DAPK1 43 12
DDR2 90 4
DYRK1A 69 2
DYRK2 79 17
DYRK3 93 7
EF2K 102 12
EIF2AK3 108 1
EPH-A2 98 9
EPH-A4 71 3
EPH-B1 102 1
EPH-B2 105 3
EPH-B3 95 13
EPH-B4 88 6
ERK1 101 22
ERK2 96 4
ERK5 95 1
ERK8 79 4
FGF-R1 96 13
GCK 87 2
GSK3 beta 96 10
HER4 73 8
HIPK1 82 1
HIPK2 93 23
HIPK3 93 4
IGF-1R 31 0
IKK beta 96 8
IKK epsilon 28 4
IR 36 2
IRAK1 83 2
IRAK4 97 16
IRR 53 1
JAK2 74 0
JNK1 104 0
JNK2 98 3
JNK3 98 1
Lck 102 10
LKB1 122 30
MAP4K3 79 6
MAP4K5 46 0
MAPKAP-K2 84 8
MAPKAP-K3 74 10
MARK1 95 14
MARK2 94 4
MARK3 100 12
MARK4 85 6
MEKK1 102 16
MELK 64 14
MINK1 89 16
MKK1 102 12
MKK2 93 0
MKK6 103 8
MLK1
6
2
MLK3
5
0
MNK1 73 11
MNK2 91 4
MPSK1 99 6
MSK1 103 3
MST2 84 4
MST3 92 11
MST4 89 11
NEK2a 97 10
NEK6 108 0
NUAK1 91 8
OSR1 103 8
p38 alpha MAPK 103 9
p38 beta MAPK 94 1
p38 delta MAPK 91 5
p38 gamma MAPK 93 5
PAK2 109 2
PAK4 98 3
PAK5 102 7
PAK6 110 3
PDGFRA 84 12
PDK1 102 16
PHK 95 1
PIM1 67 1
PIM2 112 15
PIM3 14 0
PINK 102 10
PKA 98 6
PKB alpha 91 2
PKB beta 82 8
PKC alpha 98 4
PKC gamma 83 5
PKC zeta 85 8
PKD1 102 13
PLK1 92 3
PRAK 88 1
PRK2 113 25
RIPK2 56 2
ROCK 2 86 13
RSK1 70 1
RSK2 90 2
S6K1 69 2
SGK1 79 1
SIK2 84 2
SIK3 100 3
SmMLCK 13 1
Src 85 6
SRPK1 16 1
STK33 79 5
SYK 79 10
TAK1 86 6
TAO1 109 6
TBK1 22 0
TESK1 86 6
TGFBR1 98 10
TIE2 85 2
TLK1 109 2
TrkA 49 7
TSSK1 86 2
TTBK1 107 12
TTBK2 86 8
TTK 67 0
ULK1 93 8
ULK2 89 7
VEGFR1 15 0
WNK1 105 0
YES1 94 10
ZAP70 109 7