Inhibitor | Chloroquine  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	108	6
AMPK	111	17
AMPK (hum)	106	4
ASK1	101	15
Aurora A	108	7
Aurora B	119	8
BRK	88	8
BRSK1	94	7
BRSK2	100	24
BTK	117	26
CAMK1	102	5
CAMKK beta	113	16
CDK2-Cyclin A	114	19
CDK9-Cyclin T1	99	28
CHK1	98	3
CHK2	128	24
CK1 delta	96	2
CK1 gamma 2	109	0
CK2	99	8
CLK2	111	1
CSK	103	7
DAPK1	110	15
DDR2	108	3
DYRK1A	112	2
DYRK2	104	0
DYRK3	113	14
EF2K	127	15
EIF2AK3	113	7
EPH-A2	119	11
EPH-A4	92	9
EPH-B1	117	17
EPH-B2	102	7
EPH-B3	102	7
EPH-B4	115	6
ERK1	110	3
ERK2	106	8
ERK5	100	2
ERK8	97	6
FGF-R1	116	20
GCK	113	3
GSK3 beta	127	12
HER4	115	22
HIPK1	115	13
HIPK2	117	4
HIPK3	91	11
IGF-1R	126	30
IKK beta	103	9
IKK epsilon	79	2
IR	111	6
IRAK1	113	7
IRAK4	109	7
IRR	98	8
JAK2	114	8
JNK1	101	3
JNK2	120	6
JNK3	120	16
Lck	109	15
LKB1	114	10
MAP4K3	122	22
MAP4K5	106	13
MAPKAP-K2	92	13
MAPKAP-K3	113	6
MARK1	118	2
MARK2	102	20
MARK3	112	1
MARK4	114	4
MEKK1	111	11
MELK	108	15
MINK1	94	5
MKK1	108	24
MKK2	97	16
MKK6	122	22
MLK1	115	9
MLK3	109	7
MNK1	95	33
MNK2	92	24
MPSK1	105	1
MSK1	107	8
MST2	120	2
MST3	85	19
MST4	102	3
NEK2a	79	5
NEK6	110	4
NUAK1	123	22
OSR1	108	12
p38 alpha MAPK	103	12
p38 beta MAPK	119	25
p38 delta MAPK	105	16
p38 gamma MAPK	113	1
PAK2	119	12
PAK4	109	3
PAK5	101	11
PAK6	111	2
PDGFRA	103	7
PDK1	120	6
PHK	76	4
PIM1	99	3
PIM2	101	19
PIM3	100	1
PINK	109	9
PKA	98	1
PKB alpha	107	12
PKB beta	90	1
PKC alpha	81	24
PKC gamma	112	1
PKC zeta	126	19
PKD1	133	19
PLK1	115	23
PRAK	89	18
PRK2	111	16
RIPK2	117	9
ROCK 2	123	3
RSK1	113	4
RSK2	113	1
S6K1	103	12
SGK1	115	2
SIK2	121	1
SIK3	121	14
SmMLCK	107	16
Src	127	13
SRPK1	114	20
STK33	118	15
SYK	117	7
TAK1	115	1
TAO1	114	6
TBK1	97	15
TESK1	117	18
TGFBR1	123	13
TIE2	84	1
TLK1	102	8
TrkA	105	2
TSSK1	89	8
TTBK1	111	3
TTBK2	108	1
TTK	108	2
ULK1	121	4
ULK2	95	37
VEGFR1	104	8
WNK1	105	5
YES1	85	4
ZAP70	92	3

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	101	10
AMPK	111	19
AMPK (hum)	105	4
ASK1	103	5
Aurora A	111	27
Aurora B	126	2
BRK	104	6
BRSK1	93	22
BRSK2	108	19
BTK	124	8
CAMK1	104	5
CAMKK beta	104	14
CDK2-Cyclin A	99	8
CDK9-Cyclin T1	121	12
CHK1	106	10
CHK2	119	28
CK1 delta	92	5
CK1 gamma 2	112	5
CK2	119	3
CLK2	109	5
CSK	100	5
DAPK1	94	7
DDR2	117	5
DYRK1A	107	8
DYRK2	89	0
DYRK3	106	8
EF2K	124	5
EIF2AK3	107	12
EPH-A2	100	9
EPH-A4	100	8
EPH-B1	125	27
EPH-B2	100	11
EPH-B3	109	3
EPH-B4	97	21
ERK1	108	7
ERK2	101	3
ERK5	109	12
ERK8	104	5
FGF-R1	111	8
GCK	115	9
GSK3 beta	116	3
HER4	119	23
HIPK1	107	9
HIPK2	128	4
HIPK3	101	11
IGF-1R	112	25
IKK beta	76	4
IKK epsilon	100	22
IR	100	11
IRAK1	99	2
IRAK4	112	3
IRR	106	27
JAK2	119	17
JNK1	100	9
JNK2	107	13
JNK3	116	10
Lck	109	16
LKB1	90	7
MAP4K3	114	16
MAP4K5	116	11
MAPKAP-K2	109	1
MAPKAP-K3	105	18
MARK1	96	9
MARK2	108	6
MARK3	97	14
MARK4	101	5
MEKK1	108	5
MELK	104	10
MINK1	112	17
MKK1	100	17
MKK2	115	21
MKK6	130	15
MLK1	109	1
MLK3	104	4
MNK1	115	0
MNK2	123	5
MPSK1	108	15
MSK1	101	3
MST2	107	3
MST3	98	5
MST4	106	2
NEK2a	101	31
NEK6	102	0
NUAK1	109	5
OSR1	110	13
p38 alpha MAPK	95	13
p38 beta MAPK	106	10
p38 delta MAPK	103	1
p38 gamma MAPK	108	9
PAK2	118	7
PAK4	91	9
PAK5	97	9
PAK6	111	4
PDGFRA	110	6
PDK1	112	0
PHK	83	26
PIM1	90	6
PIM2	111	26
PIM3	96	2
PINK	109	23
PKA	102	8
PKB alpha	98	1
PKB beta	117	37
PKC alpha	103	10
PKC gamma	111	1
PKC zeta	121	6
PKD1	129	44
PLK1	121	2
PRAK	84	7
PRK2	103	3
RIPK2	115	2
ROCK 2	114	1
RSK1	111	5
RSK2	117	2
S6K1	94	1
SGK1	109	14
SIK2	114	8
SIK3	125	7
SmMLCK	103	20
Src	105	2
SRPK1	111	1
STK33	121	24
SYK	111	1
TAK1	116	1
TAO1	105	11
TBK1	96	11
TESK1	118	15
TGFBR1	118	18
TIE2	81	8
TLK1	103	7
TrkA	99	15
TSSK1	105	6
TTBK1	124	2
TTBK2	112	0
TTK	110	1
ULK1	108	11
ULK2	104	2
VEGFR1	110	15
WNK1	119	3
YES1	100	7
ZAP70	102	2