Inhibitor | 1 NM-PP1 (PP1 Analog II)  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
1 NM-PP1 (PP1 Analog II)   C20H21N5 331.40 221244-14-0 5154691 Src Ira G. (2004) Nature 431 1011 Papa F.R. (2003) Science 302 1533

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 86 2
Aurora B 105 2
Aurora C 76 1
BRSK2 101 3
CAMK1 83 6
CAMKK alpha 100 1
CAMKK beta 102 6
CDK2-Cyclin A 85 4
CHK1 96 7
CHK2 83 2
CK1 delta 56 4
CK2 80 7
CSK 36 2
DYRK1A 92 8
DYRK2 94 2
DYRK3 80 4
EF2K 99 2
ERK1 84 5
ERK2 64 3
ERK8 76 0
GSK3 beta 90 3
HIPK2 95 4
HIPK3 96 3
IKK beta 98 2
JNK1 90 0
JNK2 78 1
JNK3 98 8
Lck 18 2
MAPKAP-K2 98 3
MAPKAP-K3 96 1
MARK3 71 6
MELK 66 2
MKK1 112 2
MNK1 109 8
MNK2 114 1
MSK1 78 1
MST2 45 2
NEK2a 101 6
NEK6 94 3
NEK7 110 2
p38 alpha MAPK 41 2
p38 beta MAPK 53 4
p38 delta MAPK 97 1
p38 gamma MAPK 95 0
PAK4 71 6
PAK5 74 0
PAK6 88 0
PDK1 96 1
PHK 80 5
PIM1 103 3
PIM2 101 4
PIM3 99 2
PKA 32 2
PKB alpha 82 1
PKB beta 97 4
PKC alpha 81 1
PKC zeta 82 1
PKD1 13 0
PLK1 95 4
PRAK 89 0
PRK2 109 5
ROCK 2 83 0
RSK1 83 2
RSK2 97 1
S6K1 91 7
SGK1 98 1
SmMLCK 80 7
Src 29 6
SRPK1 99 3
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 96 2
Aurora B 82 0
Aurora C 73 1
BRSK2 97 4
CAMK1 46 1
CAMKK alpha 89 4
CAMKK beta 76 2
CDK2-Cyclin A 42 5
CHK1 105 0
CHK2 44 3
CK1 delta 14 2
CK2 91 2
CSK
6
 1
DYRK1A 66 2
DYRK2 112 5
DYRK3 58 4
EF2K 105 2
ERK1 45 1
ERK2 32 7
ERK8 48 0
GSK3 beta 92 3
HIPK2 71 3
HIPK3 103 3
IKK beta 95 0
JNK1 85 4
JNK2 63 4
JNK3 79 1
Lck
3
 0
MAPKAP-K2 114 7
MAPKAP-K3 93 1
MARK3 54 2
MELK 23 0
MKK1 76 6
MNK1 105 0
MNK2 98 5
MSK1 69 2
MST2
9
 0
NEK2a 91 5
NEK6 110 1
NEK7 109 8
p38 alpha MAPK
8
 1
p38 beta MAPK 15 5
p38 delta MAPK 94 4
p38 gamma MAPK 98 2
PAK4 50 8
PAK5 47 0
PAK6 65 5
PDK1 101 0
PHK 78 3
PIM1 94 0
PIM2 103 2
PIM3 87 3
PKA
7
 1
PKB alpha 62 1
PKB beta 91 4
PKC alpha 79 2
PKC zeta 84 4
PKD1
3
 0
PLK1 94 0
PRAK 62 1
PRK2 97 2
ROCK 2 76 1
RSK1 56 6
RSK2 68 2
S6K1 82 6
SGK1 99 5
SmMLCK 71 1
Src
7
 0
SRPK1 93 0