Inhibitor | WP1130  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	98	9
ABL	98	9
AMPK	99	13
AMPK	99	13
AMPK (hum)	88	14
AMPK (hum)	88	14
ASK1	111	5
ASK1	111	5
Aurora A	93	17
Aurora A	93	17
Aurora B	93	6
Aurora B	93	6
BRK	109	18
BRK	109	18
BRSK1	99	5
BRSK1	99	5
BRSK2	121	5
BRSK2	121	5
BTK	113	6
BTK	113	6
CAMK1	87	10
CAMK1	87	10
CAMKK beta	117	7
CAMKK beta	117	7
CDK2-Cyclin A	88	1
CDK2-Cyclin A	88	1
CDK9-Cyclin T1	98	11
CDK9-Cyclin T1	98	11
CHK1	99	10
CHK1	99	10
CHK2	91	13
CHK2	91	13
CK1 delta	91	0
CK1 delta	91	0
CK1 gamma 2	108	10
CK1 gamma 2	108	10
CK2	85	12
CK2	85	12
CLK2	96	2
CLK2	96	2
CSK	89	19
CSK	89	19
DAPK1	95	36
DAPK1	95	36
DDR2	108	6
DDR2	108	6
DYRK1A	88	19
DYRK1A	88	19
DYRK2	116	24
DYRK2	116	24
DYRK3	103	9
DYRK3	103	9
EF2K	93	5
EF2K	93	5
EIF2AK3	93	9
EIF2AK3	93	9
EPH-A2	104	5
EPH-A2	104	5
EPH-A4	136	9
EPH-A4	136	9
EPH-B1	110	3
EPH-B1	110	3
EPH-B2	126	27
EPH-B2	126	27
EPH-B3	107	11
EPH-B3	107	11
EPH-B4	103	7
EPH-B4	103	7
ERK1	85	1
ERK1	85	1
ERK2	90	4
ERK2	90	4
ERK5	111	3
ERK5	111	3
ERK8	93	15
ERK8	93	15
FGF-R1	105	23
FGF-R1	105	23
GCK	97	2
GCK	97	2
GSK3 beta	98	17
GSK3 beta	98	17
HER4	108	16
HER4	108	16
HIPK1	103	9
HIPK1	103	9
HIPK2	102	6
HIPK2	102	6
HIPK3	102	18
HIPK3	102	18
IGF-1R	112	14
IGF-1R	112	14
IKK beta	95	5
IKK beta	95	5
IKK epsilon	107	5
IKK epsilon	107	5
IR	125	7
IR	125	7
IRAK1	100	7
IRAK1	100	7
IRAK4	95	6
IRAK4	95	6
IRR	109	12
IRR	109	12
JAK2	103	17
JAK2	103	17
JNK1	89	0
JNK1	89	0
JNK2	78	17
JNK2	78	17
JNK3	86	2
JNK3	86	2
Lck	89	3
Lck	89	3
LKB1	111	2
LKB1	111	2
MAP4K3	89	18
MAP4K3	89	18
MAP4K5	89	12
MAP4K5	89	12
MAPKAP-K2	61	5
MAPKAP-K2	61	5
MAPKAP-K3	108	25
MAPKAP-K3	108	25
MARK1	101	17
MARK1	101	17
MARK2	112	20
MARK2	112	20
MARK3	103	11
MARK3	103	11
MARK4	99	7
MARK4	99	7
MEKK1	103	1
MEKK1	103	1
MELK	99	22
MELK	99	22
MINK1	105	17
MINK1	105	17
MKK1	116	24
MKK1	116	24
MKK2	113	15
MKK2	113	15
MKK6	86	2
MKK6	86	2
MLK1	111	3
MLK1	111	3
MLK3	100	20
MLK3	100	20
MNK1	95	2
MNK1	95	2
MNK2	112	7
MNK2	112	7
MPSK1	93	7
MPSK1	93	7
MSK1	106	3
MSK1	106	3
MST2	97	26
MST2	97	26
MST3	111	14
MST3	111	14
MST4	107	8
MST4	107	8
NEK2a	102	7
NEK2a	102	7
NEK6	92	14
NEK6	92	14
NUAK1	100	8
NUAK1	100	8
OSR1	96	2
OSR1	96	2
p38 alpha MAPK	104	11
p38 alpha MAPK	104	11
p38 beta MAPK	91	6
p38 beta MAPK	91	6
p38 delta MAPK	97	11
p38 delta MAPK	97	11
p38 gamma MAPK	104	6
p38 gamma MAPK	104	6
PAK2	98	0
PAK2	98	0
PAK4	92	13
PAK4	92	13
PAK5	91	14
PAK5	91	14
PAK6	99	5
PAK6	99	5
PDGFRA	102	3
PDGFRA	102	3
PDK1	89	20
PDK1	89	20
PHK	97	14
PHK	97	14
PIM1	111	13
PIM1	111	13
PIM2	113	6
PIM2	113	6
PIM3	94	6
PIM3	94	6
PINK	98	15
PINK	98	15
PKA	108	16
PKA	108	16
PKB alpha	79	29
PKB alpha	79	29
PKB beta	99	2
PKB beta	99	2
PKC alpha	87	4
PKC alpha	87	4
PKC gamma	90	16
PKC gamma	90	16
PKC zeta	116	2
PKC zeta	116	2
PKD1	106	6
PKD1	106	6
PLK1	88	13
PLK1	88	13
PRAK	91	4
PRAK	91	4
PRK2	87	1
PRK2	87	1
RIPK2	100	27
RIPK2	100	27
ROCK 2	84	6
ROCK 2	84	6
RSK1	99	23
RSK1	99	23
RSK2	96	9
RSK2	96	9
S6K1	103	23
S6K1	103	23
SGK1	93	1
SGK1	93	1
SIK2	98	7
SIK2	98	7
SIK3	88	23
SIK3	88	23
SmMLCK	82	10
SmMLCK	82	10
Src	100	10
Src	100	10
SRPK1	97	7
SRPK1	97	7
STK33	91	5
STK33	91	5
SYK	116	11
SYK	116	11
TAK1	128	25
TAK1	128	25
TAO1	102	9
TAO1	102	9
TBK1	99	4
TBK1	99	4
TESK1	76	13
TESK1	76	13
TGFBR1	106	1
TGFBR1	106	1
TIE2	108	12
TIE2	108	12
TLK1	112	7
TLK1	112	7
TrkA	99	11
TrkA	99	11
TSSK1	91	8
TSSK1	91	8
TTBK1	102	3
TTBK1	102	3
TTBK2	99	3
TTBK2	99	3
TTK	106	1
TTK	106	1
ULK1	91	11
ULK1	91	11
ULK2	104	13
ULK2	104	13
VEGFR1	84	1
VEGFR1	84	1
WNK1	104	9
WNK1	104	9
YES1	126	16
YES1	126	16
ZAP70	104	1
ZAP70	104	1

Screen Conc: 5.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	92	8
ABL	92	8
AMPK	104	6
AMPK	104	6
AMPK (hum)	108	2
AMPK (hum)	108	2
ASK1	108	3
ASK1	108	3
Aurora A	82	28
Aurora A	82	28
Aurora B	86	8
Aurora B	86	8
BRK	104	16
BRK	104	16
BRSK1	102	7
BRSK1	102	7
BRSK2	102	3
BRSK2	102	3
BTK	101	10
BTK	101	10
CAMK1	75	2
CAMK1	75	2
CAMKK beta	132	22
CAMKK beta	132	22
CDK2-Cyclin A	97	6
CDK2-Cyclin A	97	6
CDK9-Cyclin T1	94	6
CDK9-Cyclin T1	94	6
CHK1	101	1
CHK1	101	1
CHK2	91	5
CHK2	91	5
CK1 delta	93	4
CK1 delta	93	4
CK1 gamma 2	102	10
CK1 gamma 2	102	10
CK2	101	29
CK2	101	29
CLK2	104	3
CLK2	104	3
CSK	105	1
CSK	105	1
DAPK1	74	11
DAPK1	74	11
DDR2	89	14
DDR2	89	14
DYRK1A	107	32
DYRK1A	107	32
DYRK2	105	10
DYRK2	105	10
DYRK3	107	3
DYRK3	107	3
EF2K	101	21
EF2K	101	21
EIF2AK3	92	5
EIF2AK3	92	5
EPH-A2	106	6
EPH-A2	106	6
EPH-A4	138	25
EPH-A4	138	25
EPH-B1	114	8
EPH-B1	114	8
EPH-B2	124	20
EPH-B2	124	20
EPH-B3	119	10
EPH-B3	119	10
EPH-B4	104	0
EPH-B4	104	0
ERK1	96	10
ERK1	96	10
ERK2	106	2
ERK2	106	2
ERK5	111	7
ERK5	111	7
ERK8	86	15
ERK8	86	15
FGF-R1	89	2
FGF-R1	89	2
GCK	90	1
GCK	90	1
GSK3 beta	97	10
GSK3 beta	97	10
HER4	89	7
HER4	89	7
HIPK1	107	10
HIPK1	107	10
HIPK2	90	6
HIPK2	90	6
HIPK3	100	16
HIPK3	100	16
IGF-1R	117	14
IGF-1R	117	14
IKK beta	82	4
IKK beta	82	4
IKK epsilon	93	6
IKK epsilon	93	6
IR	119	11
IR	119	11
IRAK1	96	34
IRAK1	96	34
IRAK4	95	22
IRAK4	95	22
IRR	108	20
IRR	108	20
JAK2	97	23
JAK2	97	23
JNK1	96	13
JNK1	96	13
JNK2	93	26
JNK2	93	26
JNK3	87	7
JNK3	87	7
Lck	93	9
Lck	93	9
LKB1	126	3
LKB1	126	3
MAP4K3	78	7
MAP4K3	78	7
MAP4K5	91	7
MAP4K5	91	7
MAPKAP-K2	73	11
MAPKAP-K2	73	11
MAPKAP-K3	98	6
MAPKAP-K3	98	6
MARK1	107	5
MARK1	107	5
MARK2	92	6
MARK2	92	6
MARK3	120	9
MARK3	120	9
MARK4	100	7
MARK4	100	7
MEKK1	95	13
MEKK1	95	13
MELK	106	3
MELK	106	3
MINK1	106	0
MINK1	106	0
MKK1	115	2
MKK1	115	2
MKK2	123	19
MKK2	123	19
MKK6	94	7
MKK6	94	7
MLK1	101	12
MLK1	101	12
MLK3	110	7
MLK3	110	7
MNK1	98	4
MNK1	98	4
MNK2	102	6
MNK2	102	6
MPSK1	103	3
MPSK1	103	3
MSK1	110	4
MSK1	110	4
MST2	110	0
MST2	110	0
MST3	102	6
MST3	102	6
MST4	111	13
MST4	111	13
NEK2a	101	30
NEK2a	101	30
NEK6	101	8
NEK6	101	8
NUAK1	101	17
NUAK1	101	17
OSR1	92	12
OSR1	92	12
p38 alpha MAPK	96	11
p38 alpha MAPK	96	11
p38 beta MAPK	97	3
p38 beta MAPK	97	3
p38 delta MAPK	93	11
p38 delta MAPK	93	11
p38 gamma MAPK	104	4
p38 gamma MAPK	104	4
PAK2	95	2
PAK2	95	2
PAK4	100	13
PAK4	100	13
PAK5	95	3
PAK5	95	3
PAK6	107	1
PAK6	107	1
PDGFRA	94	6
PDGFRA	94	6
PDK1	99	16
PDK1	99	16
PHK	105	9
PHK	105	9
PIM1	89	9
PIM1	89	9
PIM2	112	4
PIM2	112	4
PIM3	95	29
PIM3	95	29
PINK	109	20
PINK	109	20
PKA	103	11
PKA	103	11
PKB alpha	94	27
PKB alpha	94	27
PKB beta	91	10
PKB beta	91	10
PKC alpha	103	9
PKC alpha	103	9
PKC gamma	78	2
PKC gamma	78	2
PKC zeta	118	19
PKC zeta	118	19
PKD1	105	12
PKD1	105	12
PLK1	98	36
PLK1	98	36
PRAK	88	5
PRAK	88	5
PRK2	85	20
PRK2	85	20
RIPK2	107	11
RIPK2	107	11
ROCK 2	90	16
ROCK 2	90	16
RSK1	85	5
RSK1	85	5
RSK2	98	12
RSK2	98	12
S6K1	96	21
S6K1	96	21
SGK1	98	8
SGK1	98	8
SIK2	99	12
SIK2	99	12
SIK3	102	14
SIK3	102	14
SmMLCK	74	24
SmMLCK	74	24
Src	81	6
Src	81	6
SRPK1	103	10
SRPK1	103	10
STK33	101	11
STK33	101	11
SYK	119	1
SYK	119	1
TAK1	134	17
TAK1	134	17
TAO1	104	9
TAO1	104	9
TBK1	98	4
TBK1	98	4
TESK1	98	7
TESK1	98	7
TGFBR1	95	2
TGFBR1	95	2
TIE2	104	1
TIE2	104	1
TLK1	101	2
TLK1	101	2
TrkA	102	16
TrkA	102	16
TSSK1	91	12
TSSK1	91	12
TTBK1	91	3
TTBK1	91	3
TTBK2	99	9
TTBK2	99	9
TTK	101	16
TTK	101	16
ULK1	92	11
ULK1	92	11
ULK2	96	2
ULK2	96	2
VEGFR1	91	7
VEGFR1	91	7
WNK1	102	3
WNK1	102	3
YES1	111	2
YES1	111	2
ZAP70	103	7
ZAP70	103	7