Inhibitor | Leflunomide  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
PRAK	73	2
Src	74	13
BRK	82	12
DAPK1	83	12
IRAK4	84	4
PINK	87	1
TrkA	87	4
PKA	89	4
ROCK 2	90	8
RIPK2	90	5
PIM2	90	16
PIM3	90	9
ERK8	90	7
CAMKK beta	91	6
PAK6	91	13
MLK3	92	1
IKK beta	92	8
MAPKAP-K2	92	0
JNK1	93	3
TTBK2	93	3
PHK	93	5
p38 delta MAPK	93	13
VEGFR1	93	13
RSK2	94	5
MELK	94	7
CK1 gamma 2	94	10
ERK5	94	0
MAPKAP-K3	94	12
MARK4	95	3
PAK5	96	7
CDK2-Cyclin A	96	2
TIE2	96	18
IRR	97	9
PKC gamma	98	12
MSK1	98	5
PLK1	98	9
S6K1	98	1
MNK1	98	10
WNK1	98	9
DYRK2	99	2
MKK6	99	6
TBK1	99	8
p38 gamma MAPK	99	5
EPH-A2	99	3
TSSK1	99	6
EPH-A4	99	6
CK1 delta	99	5
TGFBR1	99	9
CLK2	100	9
ASK1	100	5
IRAK1	100	10
BRSK2	100	5
Aurora A	100	6
HIPK1	101	3
CHK1	101	8
NUAK1	101	3
PIM1	101	8
CAMK1	102	2
AMPK (hum)	103	14
TAO1	103	31
DYRK3	103	2
ABL	103	3
PKB alpha	103	2
ERK1	103	1
MPSK1	103	8
AMPK	104	2
TTBK1	104	24
CSK	104	1
PAK2	104	5
BRSK1	104	6
HER4	104	1
STK33	104	11
TTK	104	0
PRK2	105	13
MARK2	105	22
JNK3	105	9
PDK1	105	6
PKC alpha	105	14
SIK3	105	10
SRPK1	105	13
ULK2	105	7
CK2	105	1
DYRK1A	106	0
SGK1	106	3
MKK2	107	7
p38 alpha MAPK	107	17
TLK1	107	11
LKB1	107	10
NEK2a	108	4
PAK4	108	6
CHK2	108	11
MST4	108	1
HIPK2	109	10
MKK1	109	14
IR	109	21
CDK9-Cyclin T1	109	1
MNK2	109	13
MLK1	110	2
HIPK3	110	1
TESK1	110	24
OSR1	110	7
EIF2AK3	110	13
NEK6	111	4
YES1	112	27
MARK3	112	7
SYK	112	2
ZAP70	112	22
p38 beta MAPK	113	10
Aurora B	113	6
RSK1	114	4
PKB beta	114	4
SIK2	114	9
GCK	114	23
MAP4K5	114	9
PDGFRA	114	7
TAK1	115	12
DDR2	116	1
FGF-R1	117	6
JAK2	117	3
EPH-B3	117	11
EPH-B2	118	34
Lck	119	1
PKC zeta	119	13
MEKK1	119	5
JNK2	120	12
EPH-B4	121	14
IKK epsilon	122	5
ERK2	122	26
ULK1	122	11
MARK1	123	0
EPH-B1	124	5
EF2K	124	8
GSK3 beta	128	19
MST3	128	14
IGF-1R	130	21
SmMLCK	132	13
BTK	132	15
MST2	134	4
MAP4K3	138	20
PKD1	139	24
MINK1	143	7

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
BRK	78	7
PRAK	80	13
DAPK1	83	7
HIPK3	85	4
ERK8	85	12
MAPKAP-K2	87	3
PHK	87	9
CAMKK beta	88	4
JNK1	88	2
BRSK1	89	6
PAK5	89	6
IR	89	2
PDK1	91	3
CK1 delta	91	1
MLK3	91	6
YES1	91	3
PIM1	91	5
Aurora A	91	0
MKK6	92	7
MSK1	92	8
PIM2	92	21
IRAK4	93	10
TLK1	94	1
LKB1	94	15
ERK2	94	15
DYRK1A	94	8
S6K1	95	2
BRSK2	95	1
RIPK2	95	2
MST3	95	7
p38 delta MAPK	95	7
AMPK	96	4
TIE2	96	4
JNK3	96	7
PKA	97	0
IRR	97	4
TSSK1	97	2
MAPKAP-K3	98	3
TTBK1	98	1
CSK	98	2
PKC alpha	98	3
TTK	98	2
MPSK1	98	9
TrkA	98	9
VEGFR1	99	18
DYRK2	99	9
PAK4	99	11
IRAK1	99	13
SIK3	99	10
CAMK1	100	8
MELK	100	6
TBK1	100	4
MNK1	100	11
Aurora B	101	9
MKK2	101	5
PKC zeta	101	1
ABL	101	1
CDK9-Cyclin T1	101	0
MAP4K3	101	6
ULK2	102	8
PKB alpha	102	3
ERK1	102	2
ERK5	102	11
PINK	102	30
NEK2a	102	7
SIK2	102	8
PIM3	102	2
WNK1	102	7
MKK1	103	3
DYRK3	103	17
NUAK1	103	5
PLK1	103	2
SGK1	104	3
MARK2	104	3
ASK1	104	4
CHK1	104	1
PAK6	104	1
PDGFRA	105	18
CLK2	105	16
ROCK 2	105	7
PAK2	105	15
MARK4	105	2
EPH-A2	105	8
CHK2	105	11
IKK beta	105	17
MNK2	106	11
TAO1	106	6
p38 alpha MAPK	106	11
p38 beta MAPK	106	19
STK33	106	17
GCK	106	1
DDR2	107	3
CK2	107	0
PKC gamma	107	3
JAK2	107	26
SYK	108	0
EIF2AK3	108	7
MLK1	108	7
JNK2	108	10
PRK2	108	4
NEK6	108	12
p38 gamma MAPK	108	4
EPH-B3	109	3
MEKK1	109	7
AMPK (hum)	109	7
MARK1	109	35
SRPK1	110	10
TTBK2	110	0
TGFBR1	111	10
CDK2-Cyclin A	112	2
CK1 gamma 2	113	17
IGF-1R	113	20
EPH-A4	114	19
RSK1	114	2
RSK2	115	13
ZAP70	115	5
EPH-B4	115	16
TAK1	115	8
TESK1	116	22
GSK3 beta	116	5
EPH-B2	116	8
HIPK1	117	1
HIPK2	118	2
SmMLCK	118	6
OSR1	119	24
MST4	119	6
MINK1	121	14
Lck	121	14
ULK1	122	25
MARK3	122	5
PKD1	122	11
EF2K	124	13
BTK	125	8
MAP4K5	126	30
PKB beta	126	7
FGF-R1	127	2
EPH-B1	127	12
HER4	129	3
IKK epsilon	132	2
MST2	134	5
Src	135	9